ENSG00000177963

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000325207 ENSG00000177963 No_inf pgKDN_inf RIC8A protein_coding protein_coding 46.11245 53.87563 38.89768 3.183555 3.442739 -0.4698457 9.737126 9.987987 12.114577 1.6437620 0.8699120 0.2782250 0.22264167 0.190500 0.321675 0.131175 0.4261876 0.0160089 FALSE TRUE
ENST00000526104 ENSG00000177963 No_inf pgKDN_inf RIC8A protein_coding protein_coding 46.11245 53.87563 38.89768 3.183555 3.442739 -0.4698457 11.249768 9.766501 11.109558 0.7490311 0.7756204 0.1857093 0.25050000 0.180750 0.287325 0.106575 0.2170102 0.0160089 FALSE TRUE
ENST00000527696 ENSG00000177963 No_inf pgKDN_inf RIC8A protein_coding protein_coding 46.11245 53.87563 38.89768 3.183555 3.442739 -0.4698457 4.991460 2.903747 4.932307 1.6765004 0.3476253 0.7623093 0.11250833 0.053775 0.127625 0.073850 0.4575804 0.0160089 FALSE TRUE
ENST00000531541 ENSG00000177963 No_inf pgKDN_inf RIC8A protein_coding protein_coding_CDS_not_defined 46.11245 53.87563 38.89768 3.183555 3.442739 -0.4698457 3.514515 8.299707 0.000000 3.0065030 0.0000000 -9.6986538 0.06675833 0.152050 0.000000 -0.152050 0.0160089 0.0160089 FALSE FALSE
ENST00000532241 ENSG00000177963 No_inf pgKDN_inf RIC8A protein_coding retained_intron 46.11245 53.87563 38.89768 3.183555 3.442739 -0.4698457 8.513028 13.991858 6.084954 1.5118652 2.5539116 -1.1999311 0.17472500 0.260850 0.144025 -0.116825 0.6308436 0.0160089 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000177963 E001 35.3689432 0.0004007903 0.344078623 0.63537975 11 207708 208529 822 + 1.583 1.539 -0.152
ENSG00000177963 E002 16.0557204 0.0008763377 0.804976614 0.92782272 11 208530 208799 270 + 1.239 1.223 -0.056
ENSG00000177963 E003 7.1122292 0.0022862419 0.937415289 0.98208705 11 208800 208836 37 + 0.911 0.905 -0.022
ENSG00000177963 E004 5.8937976 0.0027165238 0.792378798 0.92074024 11 208837 208840 4 + 0.821 0.851 0.119
ENSG00000177963 E005 7.1178270 0.0020813168 0.854442581 0.94868870 11 208841 208854 14 + 0.897 0.918 0.078
ENSG00000177963 E006 18.7129988 0.0007470181 0.339310380 0.63096007 11 208855 208938 84 + 1.326 1.264 -0.216
ENSG00000177963 E007 0.0000000       11 209069 209079 11 +      
ENSG00000177963 E008 0.2537694 0.0159694931 0.274351137   11 209080 209174 95 + 0.000 0.167 11.071
ENSG00000177963 E009 0.9697569 0.0120270985 0.407668410 0.69014056 11 209175 209258 84 + 0.357 0.231 -0.859
ENSG00000177963 E010 0.9876691 0.0128676672 0.562965959 0.80259591 11 209259 209270 12 + 0.247 0.337 0.615
ENSG00000177963 E011 16.5155827 0.0158672288 0.531157996 0.78188475 11 209271 209318 48 + 1.270 1.217 -0.186
ENSG00000177963 E012 0.0000000       11 209319 209335 17 +      
ENSG00000177963 E013 0.1265070 0.0122186367 0.587483459   11 209336 209406 71 + 0.000 0.092 10.126
ENSG00000177963 E014 19.5510592 0.0006908708 0.230561142 0.51900564 11 209407 209478 72 + 1.351 1.275 -0.266
ENSG00000177963 E015 32.4232332 0.0005104221 0.006681460 0.06105691 11 209479 209629 151 + 1.592 1.454 -0.471
ENSG00000177963 E016 24.2200317 0.0035669634 0.326328319 0.61878816 11 209630 209744 115 + 1.432 1.372 -0.209
ENSG00000177963 E017 44.1805313 0.0023425053 0.143643920 0.40356735 11 209745 210000 256 + 1.614 1.685 0.242
ENSG00000177963 E018 0.1170040 0.0117585679 0.492691211   11 210364 210406 43 + 0.099 0.000 -11.167
ENSG00000177963 E019 0.1170040 0.0117585679 0.492691211   11 210407 210445 39 + 0.099 0.000 -11.167
ENSG00000177963 E020 0.1170040 0.0117585679 0.492691211   11 210446 210570 125 + 0.099 0.000 -11.167
ENSG00000177963 E021 12.0749302 0.0395263711 0.338676111 0.63030246 11 210571 210574 4 + 1.060 1.158 0.354
ENSG00000177963 E022 27.3957941 0.0131557189 0.592382769 0.82006089 11 210575 210662 88 + 1.432 1.468 0.125
ENSG00000177963 E023 1.3780158 0.0093575254 0.042214076 0.20002247 11 210663 211198 536 + 0.179 0.493 2.048
ENSG00000177963 E024 38.4339326 0.0004133624 0.360530540 0.65018010 11 211199 211349 151 + 1.616 1.575 -0.140
ENSG00000177963 E025 6.8580707 0.0212482163 0.001008429 0.01510747 11 211350 212415 1066 + 0.635 1.036 1.570
ENSG00000177963 E026 18.7142827 0.0075578267 0.390636388 0.67612657 11 212416 212467 52 + 1.326 1.264 -0.216
ENSG00000177963 E027 20.6073153 0.0019776319 0.909487133 0.97128913 11 212468 212511 44 + 1.336 1.331 -0.019
ENSG00000177963 E028 0.7535042 0.1485190937 0.158530896 0.42561628 11 212512 212596 85 + 0.099 0.337 2.200
ENSG00000177963 E029 0.9996906 0.0320278522 0.197042096 0.47819144 11 212597 212614 18 + 0.179 0.382 1.463
ENSG00000177963 E030 35.4887500 0.0003825061 0.544469207 0.79095608 11 212615 212727 113 + 1.544 1.575 0.108
ENSG00000177963 E031 19.5459973 0.0007659711 0.343425013 0.63462853 11 212728 212759 32 + 1.276 1.340 0.225
ENSG00000177963 E032 4.6094458 0.0459497097 0.011954445 0.09023785 11 212760 212836 77 + 0.518 0.879 1.516
ENSG00000177963 E033 18.5106175 0.0039784897 0.890887301 0.96365730 11 212837 212869 33 + 1.293 1.286 -0.026
ENSG00000177963 E034 35.3853094 0.0034891909 0.333675082 0.62565941 11 212870 212981 112 + 1.586 1.536 -0.172
ENSG00000177963 E035 2.2334139 0.0072444305 0.221406850 0.50855402 11 212982 213035 54 + 0.403 0.582 0.878
ENSG00000177963 E036 3.9653946 0.0763558860 0.226833236 0.51503719 11 213036 213298 263 + 0.581 0.773 0.810
ENSG00000177963 E037 43.3379098 0.0003401313 0.283696704 0.57740968 11 213299 213418 120 + 1.669 1.624 -0.154
ENSG00000177963 E038 1.2510055 0.0104301542 0.070786820 0.26943058 11 213419 213448 30 + 0.179 0.459 1.878
ENSG00000177963 E039 0.7346216 0.0140507436 0.912412308 0.97214629 11 213449 213497 49 + 0.247 0.231 -0.122
ENSG00000177963 E040 2.9792040 0.0296089116 0.185009739 0.46255865 11 213498 213780 283 + 0.483 0.677 0.878
ENSG00000177963 E041 0.4825515 0.0275851058 0.280963826   11 214206 214229 24 + 0.247 0.092 -1.707
ENSG00000177963 E042 27.9163391 0.0170301596 0.618534846 0.83495767 11 214230 214287 58 + 1.479 1.443 -0.122
ENSG00000177963 E043 121.7058742 0.0007630395 0.230551366 0.51900564 11 214288 215113 826 + 2.069 2.103 0.115

Help

Please Click HERE to learn more details about the results from DEXseq.