ENSG00000178038

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000318962 ENSG00000178038 No_inf pgKDN_inf ALS2CL protein_coding protein_coding 6.597872 17.28759 1.28733 0.9372653 0.1892029 -3.736954 1.15807087 2.9087237 0.28385233 0.03867737 0.10183032 -3.312174 0.22027500 0.169575 0.241025 0.071450 0.89871693 0.04744665 FALSE TRUE
ENST00000415953 ENSG00000178038 No_inf pgKDN_inf ALS2CL protein_coding protein_coding 6.597872 17.28759 1.28733 0.9372653 0.1892029 -3.736954 0.03075496 0.0000000 0.09226488 0.00000000 0.09226488 3.354239 0.02673333 0.000000 0.080200 0.080200 0.12704830 0.04744665 FALSE TRUE
ENST00000431015 ENSG00000178038 No_inf pgKDN_inf ALS2CL protein_coding retained_intron 6.597872 17.28759 1.28733 0.9372653 0.1892029 -3.736954 0.03366942 0.0000000 0.10100826 0.00000000 0.07468372 3.472595 0.03463333 0.000000 0.103900 0.103900 0.04744665 0.04744665 TRUE TRUE
ENST00000434140 ENSG00000178038 No_inf pgKDN_inf ALS2CL protein_coding nonsense_mediated_decay 6.597872 17.28759 1.28733 0.9372653 0.1892029 -3.736954 0.03514512 0.0000000 0.10543537 0.00000000 0.10543537 3.529013 0.02817500 0.000000 0.084525 0.084525 0.20805508 0.04744665 TRUE TRUE
ENST00000450172 ENSG00000178038 No_inf pgKDN_inf ALS2CL protein_coding retained_intron 6.597872 17.28759 1.28733 0.9372653 0.1892029 -3.736954 0.60650995 1.7597383 0.00000000 0.20952722 0.00000000 -7.467392 0.04890000 0.103850 0.000000 -0.103850 0.46300052 0.04744665 TRUE TRUE
ENST00000473484 ENSG00000178038 No_inf pgKDN_inf ALS2CL protein_coding protein_coding_CDS_not_defined 6.597872 17.28759 1.28733 0.9372653 0.1892029 -3.736954 1.19234573 3.1197243 0.25568132 0.66236852 0.15126910 -3.558267 0.16621667 0.178325 0.167650 -0.010675 0.99507265 0.04744665 FALSE TRUE
ENST00000486301 ENSG00000178038 No_inf pgKDN_inf ALS2CL protein_coding retained_intron 6.597872 17.28759 1.28733 0.9372653 0.1892029 -3.736954 0.88034728 2.3807863 0.19313532 0.29577634 0.03083573 -3.556972 0.11854167 0.136525 0.168950 0.032425 0.95837692 0.04744665 FALSE TRUE
ENST00000498817 ENSG00000178038 No_inf pgKDN_inf ALS2CL protein_coding retained_intron 6.597872 17.28759 1.28733 0.9372653 0.1892029 -3.736954 1.64965891 4.5571320 0.08125250 0.38795648 0.08125250 -5.645281 0.17814167 0.263975 0.044650 -0.219325 0.31003149 0.04744665 TRUE TRUE
MSTRG.20079.13 ENSG00000178038 No_inf pgKDN_inf ALS2CL protein_coding   6.597872 17.28759 1.28733 0.9372653 0.1892029 -3.736954 0.24712688 0.5410441 0.07226588 0.25600995 0.04903497 -2.743802 0.06019167 0.032000 0.052825 0.020825 0.99536760 0.04744665 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000178038 E001 0.0000000       3 46668995 46668996 2 -      
ENSG00000178038 E002 20.5994947 0.0006730176 0.653247701 0.85423968 3 46668997 46670281 1285 - 1.002 1.082 0.293
ENSG00000178038 E003 5.7720025 0.0027542981 0.080633842 0.29179453 3 46670282 46670564 283 - 0.830 0.585 -1.017
ENSG00000178038 E004 1.3879304 0.0097177862 0.911151972 0.97178698 3 46670565 46670571 7 - 0.261 0.238 -0.173
ENSG00000178038 E005 2.5123024 0.0061567501 0.265924978 0.55938659 3 46670572 46670598 27 - 0.540 0.350 -0.993
ENSG00000178038 E006 2.2585331 0.0120080363 0.206484711 0.49012175 3 46670599 46670599 1 - 0.540 0.321 -1.173
ENSG00000178038 E007 8.6997881 0.0154954388 0.446063518 0.72046418 3 46670600 46670783 184 - 0.830 0.742 -0.348
ENSG00000178038 E008 15.0564573 0.0011597460 0.247077319 0.53766100 3 46670784 46671064 281 - 0.773 0.966 0.740
ENSG00000178038 E009 10.0016255 0.0014988400 0.151710702 0.41520094 3 46671488 46671584 97 - 0.540 0.816 1.168
ENSG00000178038 E010 6.1939366 0.0045906214 0.680993054 0.86816715 3 46671585 46671768 184 - 0.540 0.639 0.443
ENSG00000178038 E011 2.1589302 0.0064394455 0.274705858 0.56815201 3 46671769 46671883 115 - 0.000 0.350 12.242
ENSG00000178038 E012 10.6225131 0.0086227036 0.558654096 0.80019254 3 46671884 46672033 150 - 0.708 0.830 0.487
ENSG00000178038 E013 2.0312292 0.0074071134 0.309548559 0.60286686 3 46672140 46672201 62 - 0.000 0.336 12.175
ENSG00000178038 E014 2.2759660 0.0086359010 0.791682857 0.92031242 3 46673339 46673381 43 - 0.261 0.350 0.592
ENSG00000178038 E015 11.2276708 0.0017517996 0.627169950 0.83987049 3 46674566 46674739 174 - 0.879 0.839 -0.155
ENSG00000178038 E016 13.2588969 0.0011022674 0.998911731 1.00000000 3 46674740 46675617 878 - 0.879 0.907 0.105
ENSG00000178038 E017 6.3216455 0.0065250081 0.655792225 0.85578267 3 46675618 46675686 69 - 0.540 0.646 0.474
ENSG00000178038 E018 4.3004909 0.0034740436 0.689874566 0.87258057 3 46675687 46675976 290 - 0.422 0.523 0.505
ENSG00000178038 E019 2.9185068 0.0208436562 0.147726420 0.40911305 3 46675977 46676244 268 - 0.000 0.428 12.570
ENSG00000178038 E020 6.2140166 0.0026018876 0.083883206 0.29880854 3 46676245 46676402 158 - 0.261 0.653 2.090
ENSG00000178038 E021 1.1430640 0.0107026219 1.000000000 1.00000000 3 46676429 46676641 213 - 0.000 0.219 11.527
ENSG00000178038 E022 3.5377597 0.0041547454 0.925942900 0.97773821 3 46676642 46676738 97 - 0.422 0.462 0.205
ENSG00000178038 E023 1.2507806 0.0106624688 0.204873763 0.48803770 3 46676739 46676848 110 - 0.422 0.200 -1.495
ENSG00000178038 E024 5.6633665 0.0026486498 0.401102749 0.68430948 3 46676849 46677022 174 - 0.708 0.593 -0.495
ENSG00000178038 E025 0.2533610 0.0163996819 0.703094364   3 46677180 46677265 86 - 0.000 0.059 9.711
ENSG00000178038 E026 0.3801504 0.0505369307 1.000000000   3 46677266 46677394 129 - 0.000 0.086 10.204
ENSG00000178038 E027 0.2537694 0.0163103070 0.702427027   3 46677395 46677455 61 - 0.000 0.059 9.712
ENSG00000178038 E028 3.2524933 0.0181103040 0.059714093 0.24510045 3 46678259 46678389 131 - 0.708 0.403 -1.425
ENSG00000178038 E029 2.5288842 0.0057257168 0.679876782 0.86776965 3 46679210 46679287 78 - 0.261 0.377 0.753
ENSG00000178038 E030 12.2657485 0.0069608263 0.581339519 0.81342243 3 46679288 46680399 1112 - 0.773 0.883 0.428
ENSG00000178038 E031 0.6358076 0.3865692013 1.000000000 1.00000000 3 46680400 46680429 30 - 0.000 0.135 10.659
ENSG00000178038 E032 1.6417290 0.0116018799 1.000000000 1.00000000 3 46680430 46680541 112 - 0.261 0.273 0.090
ENSG00000178038 E033 5.9468432 0.0048252023 0.342901940 0.63428080 3 46680542 46681245 704 - 0.422 0.631 0.996
ENSG00000178038 E034 3.7795443 0.0189779277 0.641313080 0.84769697 3 46681246 46681407 162 - 0.540 0.472 -0.325
ENSG00000178038 E035 0.8893257 0.3372560592 1.000000000 1.00000000 3 46681500 46681503 4 - 0.000 0.179 11.091
ENSG00000178038 E036 2.5230956 0.0059941893 0.700242231 0.87786022 3 46681504 46681573 70 - 0.422 0.364 -0.325
ENSG00000178038 E037 1.6498506 0.0083603483 0.450881043 0.72408939 3 46681574 46681598 25 - 0.000 0.289 11.943
ENSG00000178038 E038 2.3948905 0.0063764781 0.650682224 0.85292969 3 46682029 46682094 66 - 0.422 0.350 -0.408
ENSG00000178038 E039 0.8882570 0.0124412358 1.000000000 1.00000000 3 46683130 46683133 4 - 0.000 0.179 11.237
ENSG00000178038 E040 3.6471781 0.0039854425 0.252612729 0.54411734 3 46683134 46683326 193 - 0.632 0.451 -0.851
ENSG00000178038 E041 1.7756669 0.0837928311 0.435644660 0.71226784 3 46683782 46683848 67 - 0.000 0.305 11.996
ENSG00000178038 E042 2.5364709 0.0700299618 0.219169354 0.50584077 3 46683989 46684047 59 - 0.000 0.390 12.394
ENSG00000178038 E043 3.6448502 0.0047133771 0.254395591 0.54609241 3 46685525 46685644 120 - 0.632 0.451 -0.851
ENSG00000178038 E044 3.6547648 0.0040488126 0.596866159 0.82294470 3 46686308 46686439 132 - 0.540 0.462 -0.380
ENSG00000178038 E045 2.6482504 0.0055447385 0.750381874 0.90152263 3 46686983 46687148 166 - 0.422 0.377 -0.247
ENSG00000178038 E046 1.3874574 0.0097991149 0.912743370 0.97229748 3 46687619 46687684 66 - 0.261 0.238 -0.173
ENSG00000178038 E047 1.8849555 0.1498218637 0.462909791 0.73303904 3 46688098 46688296 199 - 0.422 0.289 -0.795
ENSG00000178038 E048 2.1203803 0.0589791374 0.055045831 0.23373027 3 46689338 46689465 128 - 0.632 0.289 -1.795
ENSG00000178038 E049 0.0000000       3 46693489 46693642 154 -      
ENSG00000178038 E050 0.7353160 0.0144822837 0.005360682 0.05210362 3 46693643 46693708 66 - 0.540 0.086 -3.495

Help

Please Click HERE to learn more details about the results from DEXseq.