ENSG00000178075

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358160 ENSG00000178075 No_inf pgKDN_inf GRAMD1C protein_coding protein_coding 4.150258 3.594679 2.029604 0.7364176 1.079011 -0.8215814 0.36624391 0.6541650 0.3329498 0.1607147 0.1933979 -0.9535442 0.24081667 0.216750 0.500000 0.283250 0.93355388 0.04460873 FALSE TRUE
ENST00000467895 ENSG00000178075 No_inf pgKDN_inf GRAMD1C protein_coding protein_coding_CDS_not_defined 4.150258 3.594679 2.029604 0.7364176 1.079011 -0.8215814 0.93015714 0.7714758 1.1562230 0.7714758 1.1562230 0.5775707 0.18457500 0.161875 0.222350 0.060475 0.86638217 0.04460873   FALSE
ENST00000472026 ENSG00000178075 No_inf pgKDN_inf GRAMD1C protein_coding protein_coding 4.150258 3.594679 2.029604 0.7364176 1.079011 -0.8215814 0.15373551 0.0000000 0.2244807 0.0000000 0.1310079 4.5513970 0.11240000 0.000000 0.087200 0.087200 0.31403852 0.04460873 FALSE TRUE
ENST00000484714 ENSG00000178075 No_inf pgKDN_inf GRAMD1C protein_coding nonsense_mediated_decay 4.150258 3.594679 2.029604 0.7364176 1.079011 -0.8215814 0.07951793 0.0000000 0.2385538 0.0000000 0.2385538 4.6354863 0.05010833 0.000000 0.150325 0.150325 0.75826462 0.04460873 FALSE FALSE
ENST00000491038 ENSG00000178075 No_inf pgKDN_inf GRAMD1C protein_coding retained_intron 4.150258 3.594679 2.029604 0.7364176 1.079011 -0.8215814 0.54620706 1.2367105 0.0000000 0.1022707 0.0000000 -6.9619827 0.17876667 0.403100 0.000000 -0.403100 0.04460873 0.04460873   FALSE
MSTRG.20521.14 ENSG00000178075 No_inf pgKDN_inf GRAMD1C protein_coding   4.150258 3.594679 2.029604 0.7364176 1.079011 -0.8215814 0.36289053 0.6869895 0.0000000 0.6869895 0.0000000 -6.1230650 0.10326667 0.138225 0.000000 -0.138225 0.98033149 0.04460873 FALSE FALSE
MSTRG.20521.9 ENSG00000178075 No_inf pgKDN_inf GRAMD1C protein_coding   4.150258 3.594679 2.029604 0.7364176 1.079011 -0.8215814 1.54780819 0.0000000 0.0000000 0.0000000 0.0000000 0.0000000 0.07898333 0.000000 0.000000 0.000000   0.04460873   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000178075 E001 0.0000000       3 113828182 113828279 98 +      
ENSG00000178075 E002 0.2435110 0.016974392 0.467682449   3 113838788 113838817 30 + 0.136 0.066 -1.169
ENSG00000178075 E003 0.2435110 0.016974392 0.467682449   3 113838818 113838873 56 + 0.136 0.066 -1.169
ENSG00000178075 E004 0.2435110 0.016974392 0.467682449   3 113838874 113838880 7 + 0.136 0.066 -1.169
ENSG00000178075 E005 0.2435110 0.016974392 0.467682449   3 113838881 113838899 19 + 0.136 0.066 -1.169
ENSG00000178075 E006 0.0000000       3 113838900 113838904 5 +      
ENSG00000178075 E007 0.0000000       3 113838905 113838936 32 +      
ENSG00000178075 E008 0.4998907 0.017162584 1.000000000 1.00000000 3 113844503 113844649 147 + 0.136 0.173 0.416
ENSG00000178075 E009 0.2459004 0.017456774 0.467404028   3 113844823 113844965 143 + 0.136 0.066 -1.169
ENSG00000178075 E010 0.6359336 0.146157558 0.209725866 0.49420836 3 113869507 113869591 85 + 0.000 0.259 12.998
ENSG00000178075 E011 0.7538815 0.016448905 0.520086018 0.77459678 3 113875484 113875587 104 + 0.136 0.259 1.153
ENSG00000178075 E012 0.0000000       3 113875588 113875867 280 +      
ENSG00000178075 E013 0.4994828 0.018108507 1.000000000   3 113876165 113876260 96 + 0.136 0.173 0.416
ENSG00000178075 E014 0.1271363 0.012844571 1.000000000   3 113882752 113882759 8 + 0.000 0.066 11.245
ENSG00000178075 E015 0.2536433 0.016879024 0.792250970   3 113882760 113882777 18 + 0.000 0.123 12.044
ENSG00000178075 E016 0.6338583 0.016616214 0.169923543 0.44204625 3 113882778 113882832 55 + 0.000 0.259 13.025
ENSG00000178075 E017 0.0000000       3 113890625 113890664 40 +      
ENSG00000178075 E018 0.0000000       3 113890665 113890759 95 +      
ENSG00000178075 E019 0.1272623 0.012875123 1.000000000   3 113890760 113891024 265 + 0.000 0.066 11.245
ENSG00000178075 E020 0.0000000       3 113897470 113897491 22 +      
ENSG00000178075 E021 0.0000000       3 113897492 113897813 322 +      
ENSG00000178075 E022 0.7432731 0.014937916 0.793755224 0.92135878 3 113901031 113901146 116 + 0.239 0.218 -0.169
ENSG00000178075 E023 0.9708565 0.014786894 0.044918362 0.20715066 3 113904140 113904272 133 + 0.453 0.173 -1.906
ENSG00000178075 E024 0.7148264 0.015195899 0.005206747 0.05111525 3 113908958 113908972 15 + 0.453 0.066 -3.491
ENSG00000178075 E025 1.0855997 0.012784353 0.017003540 0.11383648 3 113908973 113909120 148 + 0.505 0.173 -2.169
ENSG00000178075 E026 0.0000000       3 113913073 113913160 88 +      
ENSG00000178075 E027 0.7620020 0.056317729 0.116202450 0.35936141 3 113914549 113914591 43 + 0.000 0.297 13.202
ENSG00000178075 E028 0.6237874 0.018746646 0.703189241 0.87921483 3 113915701 113915838 138 + 0.136 0.218 0.831
ENSG00000178075 E029 0.8875631 0.015628071 0.073187922 0.27492112 3 113930714 113930832 119 + 0.000 0.331 13.366
ENSG00000178075 E030 1.0052610 0.012069987 0.282682037 0.57632770 3 113933511 113933653 143 + 0.136 0.331 1.638
ENSG00000178075 E031 0.0000000       3 113934432 113934486 55 +      
ENSG00000178075 E032 0.1176306 0.012240564 0.190636908   3 113934487 113934535 49 + 0.136 0.000 -13.578
ENSG00000178075 E033 0.6007463 0.017713261 0.016904514 0.11342723 3 113936266 113936442 177 + 0.392 0.066 -3.169
ENSG00000178075 E034 0.0000000       3 113936443 113936923 481 +      
ENSG00000178075 E035 0.1187032 0.012381463 0.190485655   3 113938086 113938143 58 + 0.136 0.000 -13.578
ENSG00000178075 E036 0.9885130 0.013698600 0.583106045 0.81433116 3 113938326 113939725 1400 + 0.322 0.259 -0.432
ENSG00000178075 E037 0.3731628 0.240902246 0.795917540   3 113939726 113939885 160 + 0.136 0.123 -0.169
ENSG00000178075 E038 1.1251600 0.039162522 0.674350806 0.86503595 3 113939886 113939996 111 + 0.239 0.331 0.638
ENSG00000178075 E039 0.2530140 0.105655098 0.825815631   3 113939997 113940239 243 + 0.000 0.123 12.025
ENSG00000178075 E040 1.8777476 0.008597800 0.440796834 0.71644928 3 113940240 113940345 106 + 0.322 0.471 0.831
ENSG00000178075 E041 12.2236628 0.001606081 0.249298318 0.54015971 3 113945398 113947174 1777 + 0.992 1.117 0.455

Help

Please Click HERE to learn more details about the results from DEXseq.