ENSG00000178209

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000322810 ENSG00000178209 No_inf pgKDN_inf PLEC protein_coding protein_coding 108.9169 22.50657 130.3352 0.4819496 1.021926 2.533279 6.2321942 0.08422255 8.245582 0.08422255 0.4393150 6.453154 0.04218333 0.003650 0.063225 0.059575 0.001054634 0.001054634 FALSE  
ENST00000398774 ENSG00000178209 No_inf pgKDN_inf PLEC protein_coding protein_coding 108.9169 22.50657 130.3352 0.4819496 1.021926 2.533279 8.7222803 0.90976911 10.085998 0.90976911 1.7142364 3.456368 0.06781667 0.039775 0.077300 0.037525 0.296743807 0.001054634 FALSE  
ENST00000436759 ENSG00000178209 No_inf pgKDN_inf PLEC protein_coding protein_coding 108.9169 22.50657 130.3352 0.4819496 1.021926 2.533279 6.5280711 2.72844723 9.189384 0.94272075 1.2347287 1.748179 0.07850000 0.120850 0.070425 -0.050425 0.779383934 0.001054634 FALSE  
MSTRG.28344.16 ENSG00000178209 No_inf pgKDN_inf PLEC protein_coding   108.9169 22.50657 130.3352 0.4819496 1.021926 2.533279 0.5639263 1.69177885 0.000000 0.97928297 0.0000000 -7.410900 0.02576667 0.077300 0.000000 -0.077300 0.179041099 0.001054634 FALSE  
MSTRG.28344.17 ENSG00000178209 No_inf pgKDN_inf PLEC protein_coding   108.9169 22.50657 130.3352 0.4819496 1.021926 2.533279 63.6375403 13.48367630 76.133120 0.62971668 0.8856332 2.496430 0.58843333 0.598325 0.584200 -0.014125 0.909112663 0.001054634 FALSE  
MSTRG.28344.3 ENSG00000178209 No_inf pgKDN_inf PLEC protein_coding   108.9169 22.50657 130.3352 0.4819496 1.021926 2.533279 13.5365652 0.70329810 18.331536 0.44367301 1.4608041 4.684466 0.09836667 0.030525 0.140475 0.109950 0.055539744 0.001054634 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000178209 E001 0.0000000       8 143915153 143915154 2 -      
ENSG00000178209 E002 0.1272623 1.232226e-02 6.304966e-02   8 143915155 143915155 1 - 0.000 0.196 11.711
ENSG00000178209 E003 793.9154721 3.374944e-05 2.752114e-04 0.0054192221 8 143915156 143916176 1021 - 2.761 2.815 0.179
ENSG00000178209 E004 1289.1573299 5.813973e-04 3.382890e-06 0.0001338612 8 143916177 143918468 2292 - 2.970 3.031 0.203
ENSG00000178209 E005 1151.5857605 7.854050e-05 9.671002e-02 0.3238518756 8 143918469 143922395 3927 - 2.934 2.922 -0.040
ENSG00000178209 E006 374.2082486 8.666362e-05 1.451959e-01 0.4054990515 8 143922504 143925884 3381 - 2.449 2.424 -0.081
ENSG00000178209 E007 31.0783335 4.261294e-04 1.181749e-01 0.3631006382 8 143926784 143926882 99 - 1.398 1.285 -0.391
ENSG00000178209 E008 37.3671450 3.677483e-04 3.300880e-02 0.1725093624 8 143926977 143927081 105 - 1.479 1.334 -0.501
ENSG00000178209 E009 29.0288865 4.800775e-04 7.392840e-01 0.8966973253 8 143927252 143927335 84 - 1.348 1.378 0.105
ENSG00000178209 E010 48.5653020 2.783659e-04 2.429284e-02 0.1428644460 8 143927410 143927766 357 - 1.588 1.454 -0.459
ENSG00000178209 E011 20.5893900 7.075377e-04 7.689355e-02 0.2835410888 8 143927854 143927992 139 - 1.234 1.074 -0.571
ENSG00000178209 E012 26.4026417 6.507125e-04 6.044454e-02 0.2466971870 8 143929103 143929281 179 - 1.335 1.185 -0.530
ENSG00000178209 E013 27.2878552 2.049023e-03 4.839652e-01 0.7483192891 8 143929414 143929571 158 - 1.335 1.285 -0.174
ENSG00000178209 E014 33.0543203 1.172705e-02 9.599728e-02 0.3227197181 8 143929646 143929829 184 - 1.428 1.285 -0.494
ENSG00000178209 E015 26.4932380 4.357926e-03 1.619361e-02 0.1105692019 8 143929936 143930062 127 - 1.344 1.133 -0.743
ENSG00000178209 E016 27.5637163 4.808815e-04 3.035009e-03 0.0348202864 8 143930144 143930298 155 - 1.364 1.114 -0.881
ENSG00000178209 E017 34.3898622 5.896967e-04 2.527009e-02 0.1462828428 8 143930384 143930536 153 - 1.446 1.285 -0.558
ENSG00000178209 E018 32.5890813 4.282414e-04 8.947359e-01 0.9652302404 8 143931534 143931659 126 - 1.401 1.398 -0.011
ENSG00000178209 E019 24.6240962 5.352585e-04 6.097127e-01 0.8301769450 8 143931937 143932032 96 - 1.277 1.322 0.159
ENSG00000178209 E020 25.4789555 5.319230e-04 9.625806e-02 0.3231007260 8 143932130 143932234 105 - 1.318 1.185 -0.470
ENSG00000178209 E021 28.8765285 4.720625e-04 2.426634e-03 0.0294372629 8 143932400 143932561 162 - 1.383 1.133 -0.880
ENSG00000178209 E022 19.3986133 6.846814e-04 1.441416e-01 0.4043511988 8 143932635 143932712 78 - 1.207 1.074 -0.474
ENSG00000178209 E023 45.3526163 3.896739e-03 8.664199e-02 0.3050438776 8 143932793 143933111 319 - 1.556 1.445 -0.381
ENSG00000178209 E024 23.3303952 2.144392e-02 1.951907e-01 0.4754743920 8 143933197 143933351 155 - 1.282 1.151 -0.463
ENSG00000178209 E025 0.3542802 2.764039e-02 1.000000e+00   8 143933626 143933680 55 - 0.119 0.000 -12.769
ENSG00000178209 E026 18.3179044 7.826163e-04 9.934713e-02 0.3291674799 8 143933998 143934091 94 - 1.186 1.030 -0.563
ENSG00000178209 E027 20.3447917 9.433112e-03 1.756381e-01 0.4497610386 8 143934318 143934445 128 - 1.226 1.095 -0.468
ENSG00000178209 E028 15.4426951 1.192620e-02 4.101567e-01 0.6921467096 8 143934635 143934730 96 - 1.079 1.168 0.318
ENSG00000178209 E029 21.2261982 1.760683e-02 3.023766e-01 0.5954677127 8 143934810 143934929 120 - 1.239 1.133 -0.379
ENSG00000178209 E030 6.1735155 2.176183e-03 8.558249e-02 0.3027949203 8 143935011 143935022 12 - 0.780 0.517 -1.137
ENSG00000178209 E031 19.6223095 7.354746e-04 4.618546e-02 0.2107560004 8 143935023 143935117 95 - 1.218 1.030 -0.674
ENSG00000178209 E032 20.9478266 6.435836e-04 1.023319e-01 0.3343271210 8 143935198 143935313 116 - 1.239 1.095 -0.515
ENSG00000178209 E033 26.4201725 1.146010e-03 6.215317e-02 0.2503780021 8 143935848 143936014 167 - 1.335 1.185 -0.530
ENSG00000178209 E034 18.2449884 1.648316e-03 6.600901e-01 0.8580929322 8 143936979 143937071 93 - 1.168 1.133 -0.126
ENSG00000178209 E035 17.1552136 9.743035e-04 2.834164e-01 0.5771348664 8 143937165 143937242 78 - 1.152 1.053 -0.359
ENSG00000178209 E036 0.7281736 5.058332e-01 2.597958e-01 0.5523577380 8 143937664 143937748 85 - 0.152 0.331 1.445
ENSG00000178209 E037 1.2229642 1.030254e-02 1.239778e-02 0.0922673853 8 143937749 143937784 36 - 0.183 0.586 2.448
ENSG00000178209 E038 20.2896138 2.499570e-03 7.314768e-01 0.8932543636 8 143938151 143938240 90 - 1.209 1.185 -0.088
ENSG00000178209 E039 0.2352613 2.418195e-01 1.000000e+00   8 143938401 143938415 15 - 0.083 0.000 -11.651
ENSG00000178209 E040 16.2863360 8.308353e-04 2.857802e-01 0.5793808299 8 143938631 143938692 62 - 1.098 1.200 0.367
ENSG00000178209 E041 0.6020099 1.834479e-01 7.517457e-01 0.9021952541 8 143938962 143939349 388 - 0.152 0.196 0.447
ENSG00000178209 E042 9.5079147 1.428350e-03 1.413404e-01 0.3998475750 8 143939350 143939635 286 - 0.932 0.746 -0.722
ENSG00000178209 E043 0.3804973 1.587562e-02 1.755354e-03   8 143942392 143942524 133 - 0.000 0.434 15.155
ENSG00000178209 E044 0.9692250 1.211299e-02 1.374389e-01 0.3945825681 8 143943779 143943958 180 - 0.183 0.434 1.711
ENSG00000178209 E045 0.0000000       8 143944648 143944737 90 -      
ENSG00000178209 E046 0.0000000       8 143946350 143946384 35 -      
ENSG00000178209 E047 0.4812643 2.424875e-02 5.803093e-01   8 143946385 143946547 163 - 0.119 0.196 0.863
ENSG00000178209 E048 19.0481579 2.516086e-03 1.157197e-01 0.3586500718 8 143950184 143951124 941 - 1.201 1.053 -0.532
ENSG00000178209 E049 0.1176306 1.173531e-02 7.388197e-01   8 143953726 143953920 195 - 0.043 0.000 -11.419
ENSG00000178209 E050 0.1272623 1.232226e-02 6.304966e-02   8 143958595 143958799 205 - 0.000 0.196 13.660
ENSG00000178209 E051 0.0000000       8 143973403 143973529 127 -      
ENSG00000178209 E052 4.8291578 3.300770e-03 2.462329e-02 0.1441789556 8 143975177 143975375 199 - 0.595 0.895 1.226
ENSG00000178209 E053 1.0797123 1.080370e-02 6.087761e-01 0.8297053463 8 143976703 143976783 81 - 0.239 0.331 0.641

Help

Please Click HERE to learn more details about the results from DEXseq.