ENSG00000178719

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000313269 ENSG00000178719 No_inf pgKDN_inf GRINA protein_coding protein_coding 307.0459 220.7812 329.8058 3.556858 5.02276 0.5789779 26.577842 19.07175 28.027034 2.741879 2.547447 0.5551405 0.08665000 0.086950 0.084850 -0.002100 1.000000000 0.003469526 FALSE  
ENST00000395068 ENSG00000178719 No_inf pgKDN_inf GRINA protein_coding protein_coding 307.0459 220.7812 329.8058 3.556858 5.02276 0.5789779 134.553422 81.16311 151.381884 2.457912 6.232671 0.8992141 0.42979167 0.367675 0.459300 0.091625 0.104843561 0.003469526 FALSE  
ENST00000525513 ENSG00000178719 No_inf pgKDN_inf GRINA protein_coding retained_intron 307.0459 220.7812 329.8058 3.556858 5.02276 0.5789779 9.628274 15.02576 3.851711 3.008630 1.351922 -1.9610852 0.03542500 0.067975 0.011575 -0.056400 0.003469526 0.003469526 FALSE  
ENST00000527194 ENSG00000178719 No_inf pgKDN_inf GRINA protein_coding protein_coding 307.0459 220.7812 329.8058 3.556858 5.02276 0.5789779 7.024956 0.00000 21.074867 0.000000 21.074867 11.0419922 0.02102500 0.000000 0.063075 0.063075 0.965131121 0.003469526 FALSE  
ENST00000533044 ENSG00000178719 No_inf pgKDN_inf GRINA protein_coding protein_coding 307.0459 220.7812 329.8058 3.556858 5.02276 0.5789779 28.609369 14.54361 39.153225 8.401970 16.142815 1.4281227 0.09108333 0.067150 0.120375 0.053225 0.835786232 0.003469526 FALSE  
ENST00000533377 ENSG00000178719 No_inf pgKDN_inf GRINA protein_coding retained_intron 307.0459 220.7812 329.8058 3.556858 5.02276 0.5789779 55.197742 55.68344 40.163631 9.206059 26.200890 -0.4712585 0.18660000 0.251325 0.119875 -0.131450 0.656815583 0.003469526 FALSE  
MSTRG.28350.7 ENSG00000178719 No_inf pgKDN_inf GRINA protein_coding   307.0459 220.7812 329.8058 3.556858 5.02276 0.5789779 38.764585 30.33429 40.770988 6.647843 13.636197 0.4264716 0.12750000 0.136325 0.124350 -0.011975 0.940598118 0.003469526 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000178719 E001 0.000000       8 143990056 143990057 2 +      
ENSG00000178719 E002 0.000000       8 143990058 143990082 25 +      
ENSG00000178719 E003 0.000000       8 143990083 143990199 117 +      
ENSG00000178719 E004 3.817802 7.178896e-03 7.355432e-02 2.759707e-01 8 143990200 143990311 112 + 0.567 0.794 0.958
ENSG00000178719 E005 0.000000       8 143990677 143990907 231 +      
ENSG00000178719 E006 59.207724 5.732333e-04 8.130992e-02 2.930417e-01 8 143991200 143991293 94 + 1.805 1.735 -0.235
ENSG00000178719 E007 120.312954 1.660496e-04 1.664761e-02 1.125012e-01 8 143991294 143991453 160 + 2.107 2.042 -0.221
ENSG00000178719 E008 67.125013 3.352096e-04 3.956449e-01 6.805738e-01 8 143991454 143991532 79 + 1.843 1.812 -0.105
ENSG00000178719 E009 30.845140 1.659182e-02 6.200003e-01 8.356415e-01 8 143991533 143991555 23 + 1.482 1.521 0.134
ENSG00000178719 E010 50.369406 1.839857e-03 2.684013e-01 5.618993e-01 8 143991556 143991602 47 + 1.684 1.735 0.173
ENSG00000178719 E011 2.872971 6.229278e-03 4.242720e-04 7.678754e-03 8 143991603 143991691 89 + 0.308 0.794 2.337
ENSG00000178719 E012 76.943864 1.682226e-03 7.273078e-01 8.911293e-01 8 143991692 143991746 55 + 1.882 1.896 0.047
ENSG00000178719 E013 88.428706 2.994624e-03 7.635065e-01 9.078324e-01 8 143991747 143991804 58 + 1.952 1.942 -0.036
ENSG00000178719 E014 3.357312 1.699730e-02 4.296659e-03 4.463363e-02 8 143991805 143991877 73 + 0.424 0.814 1.737
ENSG00000178719 E015 122.552032 2.165413e-04 1.337594e-01 3.886741e-01 8 143991878 143991949 72 + 2.069 2.111 0.140
ENSG00000178719 E016 259.064769 8.848836e-05 8.292395e-01 9.382316e-01 8 143991950 143992078 129 + 2.409 2.414 0.016
ENSG00000178719 E017 13.128459 1.362288e-03 1.684210e-06 7.319594e-05 8 143992079 143992173 95 + 0.937 1.322 1.388
ENSG00000178719 E018 11.346836 8.626401e-03 4.165433e-09 3.171693e-07 8 143992174 143992244 71 + 0.760 1.316 2.053
ENSG00000178719 E019 264.331519 1.058942e-04 6.987041e-01 8.772267e-01 8 143992245 143992373 129 + 2.423 2.416 -0.021
ENSG00000178719 E020 337.690460 9.317176e-05 9.770147e-01 9.963754e-01 8 143992465 143992608 144 + 2.525 2.527 0.004
ENSG00000178719 E021 889.604788 3.441372e-05 1.564076e-01 4.226762e-01 8 143992692 143993415 724 + 2.951 2.940 -0.037

Help

Please Click HERE to learn more details about the results from DEXseq.