ENSG00000178950

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000314167 ENSG00000178950 No_inf pgKDN_inf GAK protein_coding protein_coding 59.35574 58.10799 60.52319 3.908759 1.243198 0.05874146 22.167574 17.354887 27.9151939 1.679293 0.3857138 0.68539425 0.37654167 0.306100 0.462075 0.155975 0.20080754 0.03118572 FALSE  
ENST00000504668 ENSG00000178950 No_inf pgKDN_inf GAK protein_coding nonsense_mediated_decay 59.35574 58.10799 60.52319 3.908759 1.243198 0.05874146 13.353628 13.727251 14.1552668 1.241796 1.2149121 0.04426441 0.22148333 0.240925 0.233250 -0.007675 1.00000000 0.03118572 FALSE  
ENST00000507991 ENSG00000178950 No_inf pgKDN_inf GAK protein_coding retained_intron 59.35574 58.10799 60.52319 3.908759 1.243198 0.05874146 1.465229 4.395687 0.0000000 4.395687 0.0000000 -8.78322307 0.02153333 0.064600 0.000000 -0.064600 0.84603307 0.03118572    
ENST00000510799 ENSG00000178950 No_inf pgKDN_inf GAK protein_coding protein_coding 59.35574 58.10799 60.52319 3.908759 1.243198 0.05874146 7.945202 5.356635 11.2771777 1.998124 1.3608804 1.07259507 0.12817500 0.088650 0.186050 0.097400 0.54797950 0.03118572 FALSE  
MSTRG.21428.5 ENSG00000178950 No_inf pgKDN_inf GAK protein_coding   59.35574 58.10799 60.52319 3.908759 1.243198 0.05874146 1.686845 3.716541 0.3490611 0.607169 0.3490611 -3.37553583 0.02927500 0.063450 0.006075 -0.057375 0.03118572 0.03118572 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000178950 E001 0.0000000       4 849276 849276 1 -      
ENSG00000178950 E002 0.0000000       4 849277 849277 1 -      
ENSG00000178950 E003 0.0000000       4 849278 849278 1 -      
ENSG00000178950 E004 0.3717172 0.2007640944 6.557506e-01   4 849279 849279 1 - 0.097 0.170 0.946
ENSG00000178950 E005 0.8700998 0.0130486151 2.774607e-01 5.707368e-01 4 849280 849280 1 - 0.176 0.343 1.269
ENSG00000178950 E006 2.6308795 0.0319380088 8.193878e-03 7.024044e-02 4 849281 849282 2 - 0.300 0.706 2.034
ENSG00000178950 E007 6.1051938 0.0320470504 6.716453e-03 6.130610e-02 4 849283 849307 25 - 0.627 0.985 1.417
ENSG00000178950 E008 109.7850991 0.0001689879 1.369327e-01 3.939051e-01 4 849308 849774 467 - 2.020 2.064 0.147
ENSG00000178950 E009 66.6279878 0.0002313906 4.456506e-01 7.200204e-01 4 849892 850068 177 - 1.813 1.843 0.101
ENSG00000178950 E010 4.5947555 0.0446257583 4.882804e-02 2.176799e-01 4 850069 850409 341 - 0.573 0.860 1.187
ENSG00000178950 E011 4.0898280 0.0037582661 7.374434e-02 2.765105e-01 4 850410 850935 526 - 0.573 0.798 0.947
ENSG00000178950 E012 39.2048812 0.0028354557 2.540862e-01 5.457223e-01 4 850936 851017 82 - 1.570 1.632 0.210
ENSG00000178950 E013 29.0876680 0.0005408904 6.050374e-01 8.278215e-01 4 851018 851084 67 - 1.461 1.492 0.105
ENSG00000178950 E014 23.4287648 0.0006235285 2.472640e-18 5.823553e-16 4 851085 851749 665 - 0.977 1.577 2.117
ENSG00000178950 E015 33.8590796 0.0004019129 6.226082e-01 8.374211e-01 4 851750 851852 103 - 1.527 1.554 0.093
ENSG00000178950 E016 37.0059072 0.0004211782 9.257154e-01 9.777251e-01 4 851853 851974 122 - 1.576 1.583 0.023
ENSG00000178950 E017 9.0754000 0.0097708313 1.180734e-03 1.698632e-02 4 851975 853828 1854 - 0.795 1.130 1.255
ENSG00000178950 E018 1.9855981 0.0128607529 1.607479e-01 4.287087e-01 4 859362 859493 132 - 0.352 0.561 1.084
ENSG00000178950 E019 37.6162508 0.0003861295 9.762005e-01 9.960045e-01 4 859606 859722 117 - 1.584 1.588 0.013
ENSG00000178950 E020 36.9739252 0.0059340784 7.407468e-01 8.971486e-01 4 865122 865244 123 - 1.587 1.571 -0.053
ENSG00000178950 E021 45.2639230 0.0007184934 2.642261e-01 5.572773e-01 4 866364 866501 138 - 1.689 1.641 -0.163
ENSG00000178950 E022 17.9884033 0.0031410648 5.287643e-01 7.802778e-01 4 866502 866534 33 - 1.300 1.257 -0.152
ENSG00000178950 E023 107.1749357 0.0017046502 1.951878e-01 4.754744e-01 4 866956 867432 477 - 2.054 2.014 -0.132
ENSG00000178950 E024 36.4081522 0.0022432709 8.829544e-01 9.605624e-01 4 868539 868685 147 - 1.567 1.577 0.034
ENSG00000178950 E025 7.3030815 0.0023951467 3.330734e-09 2.592205e-07 4 868686 869957 1272 - 0.439 1.122 2.812
ENSG00000178950 E026 49.6128484 0.0018527467 1.554180e-01 4.213026e-01 4 870711 870904 194 - 1.735 1.673 -0.210
ENSG00000178950 E027 0.3798680 0.0263028953 1.131760e-01   4 872266 872773 508 - 0.000 0.236 11.694
ENSG00000178950 E028 33.8688426 0.0013022163 3.859009e-01 6.716963e-01 4 876530 876609 80 - 1.564 1.521 -0.147
ENSG00000178950 E029 36.7940034 0.0003777945 2.178338e-01 5.042908e-01 4 877090 877207 118 - 1.606 1.549 -0.197
ENSG00000178950 E030 37.0480361 0.0004438401 2.195751e-01 5.062430e-01 4 877615 877809 195 - 1.609 1.551 -0.196
ENSG00000178950 E031 25.9700396 0.0018145434 6.721222e-01 8.641091e-01 4 881907 882040 134 - 1.442 1.419 -0.081
ENSG00000178950 E032 19.0541841 0.0007194117 2.236328e-01 5.111850e-01 4 882697 882767 71 - 1.341 1.262 -0.276
ENSG00000178950 E033 15.9614250 0.0025607600 9.413051e-02 3.193019e-01 4 882768 882819 52 - 1.289 1.167 -0.430
ENSG00000178950 E034 9.8999317 0.0283136967 7.036953e-01 8.794772e-01 4 883315 883327 13 - 1.060 1.016 -0.160
ENSG00000178950 E035 28.0420857 0.0042506010 7.273713e-01 8.911463e-01 4 883328 883463 136 - 1.472 1.453 -0.066
ENSG00000178950 E036 19.1267706 0.0007632120 9.544044e-01 9.888550e-01 4 884037 884086 50 - 1.300 1.306 0.021
ENSG00000178950 E037 0.8619112 0.0149132619 7.503413e-01 9.015127e-01 4 884087 884390 304 - 0.243 0.293 0.362
ENSG00000178950 E038 7.0540279 0.0187025630 5.886444e-02 2.433026e-01 4 885783 888846 3064 - 0.777 0.995 0.835
ENSG00000178950 E039 25.2485274 0.0006001764 9.807718e-01 9.979770e-01 4 888847 888970 124 - 1.418 1.419 0.003
ENSG00000178950 E040 16.8231490 0.0145191159 6.745017e-01 8.651905e-01 4 890532 890622 91 - 1.229 1.268 0.136
ENSG00000178950 E041 15.0842682 0.0009043186 9.706134e-01 9.941400e-01 4 893377 893418 42 - 1.203 1.208 0.017
ENSG00000178950 E042 15.7609076 0.0013102271 3.981760e-01 6.822971e-01 4 893419 893489 71 - 1.254 1.195 -0.210
ENSG00000178950 E043 15.3176630 0.0110561817 5.579716e-02 2.353824e-01 4 893874 893942 69 - 1.289 1.130 -0.562
ENSG00000178950 E044 14.6770840 0.0018866708 6.840947e-01 8.692355e-01 4 893943 894009 67 - 1.210 1.181 -0.101
ENSG00000178950 E045 9.4667906 0.0659002175 6.842558e-03 6.212904e-02 4 894010 894827 818 - 0.777 1.160 1.433
ENSG00000178950 E046 8.3189861 0.0016717147 6.799361e-01 8.677737e-01 4 896460 896468 9 - 0.988 0.951 -0.138
ENSG00000178950 E047 18.4741226 0.0007531153 5.084860e-01 7.667567e-01 4 896469 896549 81 - 1.311 1.268 -0.149
ENSG00000178950 E048 1.1230525 0.0192250413 1.053570e-01 3.396081e-01 4 897976 898032 57 - 0.176 0.428 1.754
ENSG00000178950 E049 15.6338171 0.0009221088 2.654979e-01 5.588263e-01 4 898033 898061 29 - 1.260 1.181 -0.279
ENSG00000178950 E050 23.2011179 0.0005987985 1.481846e-01 4.098980e-01 4 898062 898158 97 - 1.426 1.341 -0.297
ENSG00000178950 E051 10.8257696 0.0012155538 4.678349e-02 2.123923e-01 4 904637 904652 16 - 1.153 0.985 -0.611
ENSG00000178950 E052 15.2935476 0.0009027680 4.985361e-01 7.589854e-01 4 904653 904686 34 - 1.236 1.188 -0.169
ENSG00000178950 E053 24.3008630 0.0005644923 1.344611e-01 3.898518e-01 4 904687 904774 88 - 1.446 1.359 -0.300
ENSG00000178950 E054 11.2047616 0.0020556063 1.021500e-01 3.340018e-01 4 904775 904779 5 - 1.153 1.016 -0.496
ENSG00000178950 E055 0.3709943 0.0166288708 6.100628e-01   4 904780 904781 2 - 0.097 0.170 0.947
ENSG00000178950 E056 15.3624866 0.0008668402 9.851944e-02 3.274997e-01 4 911673 911718 46 - 1.272 1.153 -0.422
ENSG00000178950 E057 13.6268952 0.0011367030 5.642287e-02 2.369471e-01 4 911719 911787 69 - 1.236 1.090 -0.521
ENSG00000178950 E058 0.3644776 0.0166542168 5.582077e-01   4 911788 911842 55 - 0.176 0.094 -1.053
ENSG00000178950 E059 0.3641952 0.0166474853 5.579948e-01   4 912030 912084 55 - 0.176 0.094 -1.053
ENSG00000178950 E060 0.7256838 0.0139747584 3.855370e-01 6.715049e-01 4 912085 912174 90 - 0.300 0.170 -1.053
ENSG00000178950 E061 0.8517789 0.0148669744 6.670988e-01 8.615259e-01 4 912462 912734 273 - 0.300 0.236 -0.468
ENSG00000178950 E062 12.8035622 0.0403964951 3.540602e-01 6.437799e-01 4 912735 912794 60 - 1.196 1.081 -0.413
ENSG00000178950 E063 15.5880699 0.0035987586 7.136727e-01 8.846792e-01 4 913607 913668 62 - 1.203 1.233 0.106
ENSG00000178950 E064 0.0000000       4 913669 914029 361 -      
ENSG00000178950 E065 0.1271363 0.0123846412 5.611292e-01   4 915498 915756 259 - 0.000 0.094 10.262
ENSG00000178950 E066 19.4693269 0.0007832356 6.170805e-01 8.341467e-01 4 932043 932379 337 - 1.326 1.295 -0.108

Help

Please Click HERE to learn more details about the results from DEXseq.