ENSG00000178951

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000322357 ENSG00000178951 No_inf pgKDN_inf ZBTB7A protein_coding protein_coding 37.40512 23.22023 42.75696 0.3655643 0.665098 0.8804933 17.846636 14.312236 21.519319 2.05786788 1.4639245 0.5880460 0.5031417 0.617275 0.503050 -0.114225 0.71706299 0.00206135 FALSE TRUE
ENST00000601588 ENSG00000178951 No_inf pgKDN_inf ZBTB7A protein_coding protein_coding 37.40512 23.22023 42.75696 0.3655643 0.665098 0.8804933 10.146073 2.030342 12.286992 0.05014152 1.0260845 2.5914225 0.2403583 0.087500 0.286875 0.199375 0.00206135 0.00206135 FALSE TRUE
MSTRG.14312.1 ENSG00000178951 No_inf pgKDN_inf ZBTB7A protein_coding   37.40512 23.22023 42.75696 0.3655643 0.665098 0.8804933 3.775318 4.479242 2.455944 1.30358137 0.3397909 -0.8643321 0.1147167 0.190600 0.057500 -0.133100 0.18832435 0.00206135 FALSE TRUE
MSTRG.14312.4 ENSG00000178951 No_inf pgKDN_inf ZBTB7A protein_coding   37.40512 23.22023 42.75696 0.3655643 0.665098 0.8804933 4.812526 2.398408 6.494705 2.39840822 2.1664956 1.4334036 0.1237000 0.104625 0.152575 0.047950 0.41555783 0.00206135 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000178951 E001 0.7347749 0.0554972886 6.965834e-01 8.760960e-01 19 4043271 4043300 30 - 0.211 0.270 0.458
ENSG00000178951 E002 0.8524055 0.0779240524 9.543406e-01 9.888285e-01 19 4043301 4043302 2 - 0.264 0.270 0.044
ENSG00000178951 E003 2.3211093 0.0076151257 6.313987e-01 8.419057e-01 19 4043303 4043329 27 - 0.490 0.554 0.307
ENSG00000178951 E004 580.6951182 0.0005209461 7.686720e-08 4.586013e-06 19 4043330 4047741 4412 - 2.742 2.785 0.140
ENSG00000178951 E005 128.7074285 0.0002135870 1.008070e-01 3.314189e-01 19 4047742 4048244 503 - 2.130 2.083 -0.158
ENSG00000178951 E006 213.8056008 0.0039367222 2.294863e-04 4.686526e-03 19 4053971 4055247 1277 - 2.373 2.264 -0.364
ENSG00000178951 E007 4.4540929 0.0101742994 1.061569e-02 8.351032e-02 19 4055374 4055801 428 - 0.570 0.881 1.282
ENSG00000178951 E008 1.2443275 0.0106621154 7.562385e-02 2.809407e-01 19 4057505 4057563 59 - 0.211 0.478 1.682
ENSG00000178951 E009 5.0587827 0.0031102430 3.685951e-02 1.848597e-01 19 4065430 4065732 303 - 0.873 0.619 -1.036
ENSG00000178951 E010 12.7322173 0.0010952505 2.407364e-01 5.299541e-01 19 4066682 4066899 218 - 1.176 1.076 -0.359
ENSG00000178951 E011 0.4798448 0.0153389967 5.026662e-01   19 4067141 4067178 38 - 0.211 0.110 -1.126

Help

Please Click HERE to learn more details about the results from DEXseq.