ENSG00000178980

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000593892 ENSG00000178980 No_inf pgKDN_inf SELENOW protein_coding protein_coding 50.92785 52.30013 51.36528 2.265466 2.351241 -0.02601609 6.199421 6.518639 7.848938 2.1955115 3.9232936 0.2675520 0.11930833 0.124050 0.146400 0.022350 1.00000000 0.02375816    
ENST00000598273 ENSG00000178980 No_inf pgKDN_inf SELENOW protein_coding retained_intron 50.92785 52.30013 51.36528 2.265466 2.351241 -0.02601609 2.994909 4.303004 1.740513 0.4205101 0.2104948 -1.3009151 0.05908333 0.083050 0.034225 -0.048825 0.31901940 0.02375816    
ENST00000601048 ENSG00000178980 No_inf pgKDN_inf SELENOW protein_coding protein_coding 50.92785 52.30013 51.36528 2.265466 2.351241 -0.02601609 35.665269 32.699417 39.669704 3.0853828 2.9879105 0.2786952 0.70159167 0.622825 0.778225 0.155400 0.33177737 0.02375816    
MSTRG.15401.6 ENSG00000178980 No_inf pgKDN_inf SELENOW protein_coding   50.92785 52.30013 51.36528 2.265466 2.351241 -0.02601609 1.678058 4.620042 0.000000 1.6838946 0.0000000 -8.8548816 0.03325000 0.090725 0.000000 -0.090725 0.02375816 0.02375816    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000178980 E001 0.3638483 0.0167563425 3.778026e-01   19 47778677 47778682 6 + 0.200 0.081 -1.516
ENSG00000178980 E002 0.8613496 0.0125518323 9.111395e-01 0.9717869788 19 47778683 47778690 8 + 0.274 0.260 -0.100
ENSG00000178980 E003 1.6040584 0.0102409095 8.687884e-01 0.9548706505 19 47778691 47778700 10 + 0.392 0.421 0.163
ENSG00000178980 E004 1.6040584 0.0102409095 8.687884e-01 0.9548706505 19 47778701 47778702 2 + 0.392 0.421 0.163
ENSG00000178980 E005 1.6040584 0.0102409095 8.687884e-01 0.9548706505 19 47778703 47778703 1 + 0.392 0.421 0.163
ENSG00000178980 E006 3.0700566 0.0056114509 7.452430e-01 0.8992133505 19 47778704 47778708 5 + 0.625 0.587 -0.168
ENSG00000178980 E007 18.0942381 0.0009841520 6.001509e-01 0.8248078820 19 47778709 47778814 106 + 1.289 1.260 -0.100
ENSG00000178980 E008 4.7161013 0.0030092983 2.435580e-01 0.5335911118 19 47778933 47779238 306 + 0.654 0.801 0.600
ENSG00000178980 E009 5.6117881 0.0028170939 2.182703e-02 0.1341347568 19 47779239 47779496 258 + 0.625 0.901 1.113
ENSG00000178980 E010 3.3838741 0.1640603479 1.131629e-01 0.3538611246 19 47779497 47779647 151 + 0.392 0.741 1.622
ENSG00000178980 E011 2.9819182 0.0381617132 2.793009e-01 0.5725727117 19 47779648 47779856 209 + 0.484 0.651 0.765
ENSG00000178980 E012 7.9057740 0.0020852904 5.925923e-01 0.8203088077 19 47779857 47780387 531 + 0.904 0.963 0.222
ENSG00000178980 E013 8.6403036 0.0143946058 3.432316e-04 0.0064862842 19 47780388 47780563 176 + 0.682 1.096 1.591
ENSG00000178980 E014 9.4128442 0.0044332895 4.969368e-06 0.0001875563 19 47780564 47780724 161 + 0.654 1.143 1.877
ENSG00000178980 E015 13.5501671 0.0010991585 1.225930e-02 0.0916668512 19 47780725 47780749 25 + 1.016 1.224 0.751
ENSG00000178980 E016 0.5078857 0.0159249228 1.016114e-01 0.3328584118 19 47780756 47780814 59 + 0.000 0.260 11.671
ENSG00000178980 E017 0.2541163 0.0160685927 3.991279e-01   19 47780815 47780863 49 + 0.000 0.149 10.773
ENSG00000178980 E018 17.6825963 0.0092511101 2.581741e-01 0.5504787222 19 47780864 47780917 54 + 1.202 1.297 0.336
ENSG00000178980 E019 0.4992614 0.0153128245 5.315037e-01   19 47780918 47781000 83 + 0.111 0.208 1.069
ENSG00000178980 E020 0.4887509 0.0159019141 7.114695e-01   19 47781001 47781079 79 + 0.200 0.149 -0.515
ENSG00000178980 E021 0.6251106 0.0149539805 3.358634e-01 0.6277536129 19 47781080 47781107 28 + 0.111 0.260 1.485
ENSG00000178980 E022 30.3817634 0.0005466192 5.167238e-03 0.0508094418 19 47781108 47781182 75 + 1.565 1.428 -0.469
ENSG00000178980 E023 42.0128002 0.0005838170 3.053325e-04 0.0058855629 19 47781290 47781388 99 + 1.708 1.559 -0.507
ENSG00000178980 E024 0.1272623 0.0124788983 7.859268e-01   19 47781389 47781556 168 + 0.000 0.081 9.849
ENSG00000178980 E025 9.2112761 0.0025829282 2.707481e-02 0.1529669989 19 47782180 47784289 2110 + 0.854 1.074 0.820
ENSG00000178980 E026 40.3910018 0.0016133223 5.432077e-01 0.7901844652 19 47784290 47784405 116 + 1.620 1.599 -0.072
ENSG00000178980 E027 52.5245214 0.0003296972 3.240424e-03 0.0365855178 19 47784406 47784686 281 + 1.779 1.675 -0.354

Help

Please Click HERE to learn more details about the results from DEXseq.