ENSG00000178999

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000316199 ENSG00000178999 No_inf pgKDN_inf AURKB protein_coding protein_coding 12.80993 9.697367 12.76804 1.425761 2.980393 0.3965147 0.7379034 1.8987729 0.0000000 1.1598604 0.0000000 -7.57650168 0.09163333 0.254725 0.000000 -0.254725 0.54291005 0.02130803 FALSE TRUE
ENST00000534871 ENSG00000178999 No_inf pgKDN_inf AURKB protein_coding protein_coding 12.80993 9.697367 12.76804 1.425761 2.980393 0.3965147 1.9578175 2.4891138 2.4439180 0.8956063 1.6027358 -0.02632956 0.14540000 0.238425 0.141250 -0.097175 0.82371024 0.02130803 FALSE TRUE
ENST00000578549 ENSG00000178999 No_inf pgKDN_inf AURKB protein_coding protein_coding 12.80993 9.697367 12.76804 1.425761 2.980393 0.3965147 0.3093196 0.0000000 0.7610607 0.0000000 0.4464996 6.26877246 0.03234167 0.000000 0.086325 0.086325 0.59970148 0.02130803 FALSE TRUE
ENST00000578753 ENSG00000178999 No_inf pgKDN_inf AURKB protein_coding retained_intron 12.80993 9.697367 12.76804 1.425761 2.980393 0.3965147 0.9904566 0.8868895 0.6321849 0.8868895 0.6321849 -0.48194143 0.06072500 0.065275 0.029600 -0.035675 1.00000000 0.02130803 FALSE FALSE
ENST00000583124 ENSG00000178999 No_inf pgKDN_inf AURKB protein_coding retained_intron 12.80993 9.697367 12.76804 1.425761 2.980393 0.3965147 1.1576165 0.5987848 1.3571812 0.5987848 1.3571812 1.16720032 0.07432500 0.063550 0.063525 -0.000025 1.00000000 0.02130803   FALSE
ENST00000584561 ENSG00000178999 No_inf pgKDN_inf AURKB protein_coding retained_intron 12.80993 9.697367 12.76804 1.425761 2.980393 0.3965147 0.5000748 1.0255195 0.0000000 0.5995313 0.0000000 -6.69421089 0.04190000 0.094050 0.000000 -0.094050 0.41457658 0.02130803 TRUE TRUE
ENST00000584972 ENSG00000178999 No_inf pgKDN_inf AURKB protein_coding protein_coding 12.80993 9.697367 12.76804 1.425761 2.980393 0.3965147 0.3936804 1.1810413 0.0000000 1.1810413 0.0000000 -6.89607958 0.02897500 0.086925 0.000000 -0.086925 0.83308949 0.02130803 FALSE TRUE
ENST00000585124 ENSG00000178999 No_inf pgKDN_inf AURKB protein_coding protein_coding 12.80993 9.697367 12.76804 1.425761 2.980393 0.3965147 4.4124298 0.0000000 5.4043199 0.0000000 1.8437584 9.08063633 0.34695833 0.000000 0.551100 0.551100 0.02130803 0.02130803 FALSE TRUE
MSTRG.12020.4 ENSG00000178999 No_inf pgKDN_inf AURKB protein_coding   12.80993 9.697367 12.76804 1.425761 2.980393 0.3965147 0.7986414 1.3083174 0.4987144 0.7951345 0.1078425 -1.37376978 0.08052500 0.163625 0.042525 -0.121100 0.95406438 0.02130803 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000178999 E001 0.0000000       17 8204733 8204733 1 -      
ENSG00000178999 E002 0.1170040 0.012154127 0.659574160   17 8204734 8204742 9 - 0.086 0.000 -10.425
ENSG00000178999 E003 0.2340080 0.376278459 0.409380270   17 8204743 8204747 5 - 0.158 0.000 -11.424
ENSG00000178999 E004 0.6069838 0.184197494 0.794662883 0.92180066 17 8204748 8204753 6 - 0.220 0.189 -0.278
ENSG00000178999 E005 3.0854189 0.004893042 0.133054874 0.38734380 17 8204754 8204858 105 - 0.505 0.706 0.891
ENSG00000178999 E006 2.5632060 0.006332559 0.847471120 0.94593351 17 8204859 8204870 12 - 0.561 0.538 -0.109
ENSG00000178999 E007 3.5331797 0.020181896 0.723881989 0.88905681 17 8204871 8204901 31 - 0.676 0.630 -0.197
ENSG00000178999 E008 5.2396372 0.002896504 0.675406114 0.86552210 17 8204902 8204960 59 - 0.813 0.771 -0.168
ENSG00000178999 E009 6.8251020 0.002000479 0.739938903 0.89686991 17 8204961 8205044 84 - 0.906 0.877 -0.109
ENSG00000178999 E010 4.6209014 0.003335524 0.489697387 0.75261778 17 8205216 8205264 49 - 0.783 0.706 -0.311
ENSG00000178999 E011 3.6313728 0.004143952 0.191561774 0.47116439 17 8205265 8205317 53 - 0.733 0.571 -0.694
ENSG00000178999 E012 6.1173538 0.002791654 0.670393721 0.86303891 17 8205318 8205390 73 - 0.828 0.877 0.190
ENSG00000178999 E013 4.2829426 0.003755663 0.671959171 0.86407132 17 8206491 8206492 2 - 0.696 0.750 0.223
ENSG00000178999 E014 5.5935818 0.003390456 0.604852917 0.82776293 17 8206493 8206518 26 - 0.842 0.790 -0.201
ENSG00000178999 E015 4.4767344 0.048938696 0.261891906 0.55463455 17 8206519 8206537 19 - 0.798 0.657 -0.578
ENSG00000178999 E016 8.6308481 0.013540395 0.492788557 0.75486546 17 8206538 8206639 102 - 1.011 0.949 -0.228
ENSG00000178999 E017 0.4982242 0.499934976 0.466087368   17 8206640 8206698 59 - 0.086 0.259 1.888
ENSG00000178999 E018 0.1272623 0.012991425 0.437566041   17 8206740 8206749 10 - 0.000 0.105 10.931
ENSG00000178999 E019 8.6829496 0.002962450 0.616844073 0.83407212 17 8206750 8206888 139 - 0.961 1.011 0.184
ENSG00000178999 E020 1.5973183 0.009265747 0.524486573 0.77760346 17 8206889 8206934 46 - 0.366 0.463 0.528
ENSG00000178999 E021 2.8767107 0.006933843 0.001191276 0.01711059 17 8206935 8207175 241 - 0.322 0.771 2.154
ENSG00000178999 E022 5.6425429 0.063392629 0.457985983 0.72989232 17 8207176 8207241 66 - 0.767 0.877 0.430
ENSG00000178999 E023 5.6334540 0.002742023 0.490704845 0.75323529 17 8207242 8207317 76 - 0.783 0.861 0.306
ENSG00000178999 E024 4.6312858 0.003297393 0.718582730 0.88671520 17 8207318 8207367 50 - 0.767 0.729 -0.154
ENSG00000178999 E025 0.6185329 0.074806027 0.524963105 0.77786093 17 8207368 8207370 3 - 0.158 0.259 0.890
ENSG00000178999 E026 4.9712704 0.003329327 0.156307283 0.42255772 17 8207571 8207625 55 - 0.842 0.682 -0.642
ENSG00000178999 E027 5.5627044 0.003149620 0.041789055 0.19889260 17 8207738 8207840 103 - 0.906 0.682 -0.887
ENSG00000178999 E028 0.3634701 0.016707693 0.717360421   17 8207841 8207901 61 - 0.158 0.105 -0.694
ENSG00000178999 E029 0.4991656 0.017656098 0.233610073   17 8207902 8208225 324 - 0.086 0.259 1.891
ENSG00000178999 E030 0.4899771 0.015861095 0.843022881   17 8209954 8209997 44 - 0.158 0.189 0.306
ENSG00000178999 E031 0.0000000       17 8209998 8210055 58 -      
ENSG00000178999 E032 0.2459655 0.016874470 0.873940623   17 8210056 8210176 121 - 0.086 0.105 0.306
ENSG00000178999 E033 2.0695194 0.177614753 0.761342471 0.90682801 17 8210177 8210225 49 - 0.506 0.463 -0.210
ENSG00000178999 E034 1.8518161 0.132487824 0.335450542 0.62728818 17 8210226 8210249 24 - 0.366 0.538 0.890
ENSG00000178999 E035 0.3808443 0.022827562 0.070823533   17 8210250 8210254 5 - 0.000 0.259 12.516
ENSG00000178999 E036 2.4595224 0.138020914 0.493209763 0.75518796 17 8210530 8210600 71 - 0.475 0.601 0.594

Help

Please Click HERE to learn more details about the results from DEXseq.