ENSG00000179151

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000315127 ENSG00000179151 No_inf pgKDN_inf EDC3 protein_coding protein_coding 15.8025 12.35317 13.94147 0.6456553 0.7297657 0.1743688 9.8606996 9.36910553 10.3919311 0.24535856 0.2844604 0.1493291 0.66340000 0.763925 0.754050 -0.009875 1.0000000 0.0407908 FALSE TRUE
ENST00000566219 ENSG00000179151 No_inf pgKDN_inf EDC3 protein_coding protein_coding 15.8025 12.35317 13.94147 0.6456553 0.7297657 0.1743688 0.3684133 0.00000000 1.1052399 0.00000000 1.1052399 6.8012102 0.02505000 0.000000 0.075150 0.075150 0.8490497 0.0407908 FALSE FALSE
ENST00000568176 ENSG00000179151 No_inf pgKDN_inf EDC3 protein_coding protein_coding 15.8025 12.35317 13.94147 0.6456553 0.7297657 0.1743688 1.0809686 0.07317107 0.7192762 0.07317107 0.7192762 3.1323118 0.06008333 0.005975 0.051475 0.045500 0.9877700 0.0407908 FALSE TRUE
ENST00000569561 ENSG00000179151 No_inf pgKDN_inf EDC3 protein_coding protein_coding 15.8025 12.35317 13.94147 0.6456553 0.7297657 0.1743688 0.3366937 0.00000000 1.0100810 0.00000000 1.0100810 6.6725399 0.02215000 0.000000 0.066450 0.066450 0.8466332 0.0407908 FALSE FALSE
ENST00000569606 ENSG00000179151 No_inf pgKDN_inf EDC3 protein_coding retained_intron 15.8025 12.35317 13.94147 0.6456553 0.7297657 0.1743688 2.1035169 1.83622071 0.0000000 0.66969273 0.0000000 -7.5284312 0.12691667 0.146425 0.000000 -0.146425 0.0407908 0.0407908   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000179151 E001 1.1357331 0.0418828152 1.340260e-02 0.097197223 15 74630558 74630574 17 - 0.092 0.480 3.091
ENSG00000179151 E002 88.4314733 0.0002245737 6.951019e-05 0.001744515 15 74630575 74632124 1550 - 1.899 1.998 0.333
ENSG00000179151 E003 17.1036681 0.0249231321 7.096082e-01 0.882508846 15 74632125 74632508 384 - 1.274 1.241 -0.115
ENSG00000179151 E004 4.0623588 0.0808747187 3.961432e-01 0.680931505 15 74632509 74632541 33 - 0.635 0.763 0.533
ENSG00000179151 E005 14.2617988 0.0012404473 1.373757e-01 0.394547831 15 74632542 74632732 191 - 1.125 1.235 0.391
ENSG00000179151 E006 10.0381185 0.0017242448 6.459720e-03 0.059484124 15 74632733 74632946 214 - 1.147 0.907 -0.882
ENSG00000179151 E007 0.0000000       15 74635181 74635408 228 -      
ENSG00000179151 E008 0.0000000       15 74635409 74635561 153 -      
ENSG00000179151 E009 0.0000000       15 74635562 74635626 65 -      
ENSG00000179151 E010 0.0000000       15 74635627 74635727 101 -      
ENSG00000179151 E011 0.0000000       15 74640466 74640560 95 -      
ENSG00000179151 E012 0.0000000       15 74640561 74640619 59 -      
ENSG00000179151 E013 3.8083636 0.0039506523 4.761090e-01 0.742731748 15 74655733 74655793 61 - 0.635 0.724 0.372
ENSG00000179151 E014 17.9230404 0.0008898449 2.941855e-01 0.587547995 15 74655794 74656019 226 - 1.311 1.241 -0.244
ENSG00000179151 E015 6.9364716 0.0020960558 2.208986e-01 0.507875860 15 74656020 74656068 49 - 0.957 0.833 -0.472
ENSG00000179151 E016 6.0568117 0.0026227983 3.973620e-02 0.193196788 15 74671455 74671544 90 - 0.946 0.724 -0.865
ENSG00000179151 E017 2.6573651 0.0053399802 1.174173e-01 0.361961449 15 74671545 74671567 23 - 0.659 0.442 -1.008
ENSG00000179151 E018 4.6190093 0.0034109563 2.706560e-01 0.564331332 15 74671568 74671634 67 - 0.810 0.680 -0.525
ENSG00000179151 E019 4.1490420 0.0500626590 6.616514e-01 0.858756744 15 74671635 74671661 27 - 0.741 0.680 -0.250
ENSG00000179151 E020 8.3095529 0.0166648858 6.877772e-01 0.871255530 15 74671662 74671774 113 - 0.990 0.946 -0.164
ENSG00000179151 E021 0.0000000       15 74674861 74674960 100 -      
ENSG00000179151 E022 7.6622548 0.0019948494 1.628502e-01 0.431380038 15 74674961 74675030 70 - 1.000 0.864 -0.513
ENSG00000179151 E023 9.3631467 0.0020274367 1.493128e-01 0.411549933 15 74675031 74675142 112 - 1.076 0.946 -0.478
ENSG00000179151 E024 0.7441571 0.0141848332 3.710871e-01 0.659121000 15 74676941 74677022 82 - 0.169 0.303 1.092
ENSG00000179151 E025 0.0000000       15 74679802 74679925 124 -      
ENSG00000179151 E026 0.7266267 0.0138620257 4.589562e-01 0.730704392 15 74687091 74687129 39 - 0.290 0.178 -0.908
ENSG00000179151 E027 0.8442573 0.0126278592 2.887182e-01 0.582235604 15 74687130 74687179 50 - 0.340 0.178 -1.230
ENSG00000179151 E028 0.3621491 0.0166389785 6.235315e-01   15 74692886 74693018 133 - 0.169 0.098 -0.908
ENSG00000179151 E029 0.0000000       15 74695326 74695369 44 -      
ENSG00000179151 E030 0.0000000       15 74695370 74695422 53 -      
ENSG00000179151 E031 0.0000000       15 74695423 74695879 457 -      
ENSG00000179151 E032 5.8564877 0.0081006338 7.299016e-01 0.892462329 15 74695880 74696030 151 - 0.855 0.817 -0.149
ENSG00000179151 E033 0.0000000       15 74696186 74696292 107 -      

Help

Please Click HERE to learn more details about the results from DEXseq.