ENSG00000179335

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000395066 ENSG00000179335 No_inf pgKDN_inf CLK3 protein_coding protein_coding 43.11834 47.71664 40.23846 2.986072 2.100098 -0.245861 22.507038 17.858893 26.9262335 0.9190902 1.278326 0.5920979 0.53746667 0.377975 0.675800 0.297825 0.002783699 0.002783699 FALSE TRUE
ENST00000562626 ENSG00000179335 No_inf pgKDN_inf CLK3 protein_coding retained_intron 43.11834 47.71664 40.23846 2.986072 2.100098 -0.245861 1.054224 3.162672 0.0000000 1.8389792 0.000000 -8.3095546 0.02282500 0.068475 0.000000 -0.068475 0.527556740 0.002783699 FALSE FALSE
ENST00000568232 ENSG00000179335 No_inf pgKDN_inf CLK3 protein_coding retained_intron 43.11834 47.71664 40.23846 2.986072 2.100098 -0.245861 3.985715 4.136197 3.1739976 0.7400021 1.449622 -0.3809492 0.09228333 0.089425 0.074125 -0.015300 0.856002772 0.002783699   FALSE
MSTRG.9930.11 ENSG00000179335 No_inf pgKDN_inf CLK3 protein_coding   43.11834 47.71664 40.23846 2.986072 2.100098 -0.245861 1.711655 4.232615 0.7176227 1.7229898 0.530466 -2.5436913 0.03941667 0.094575 0.018950 -0.075625 0.560946428 0.002783699 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000179335 E001 0.4982540 0.0152079343 4.556694e-01   15 74598500 74599537 1038 + 0.106 0.218 1.237
ENSG00000179335 E002 0.4975013 0.0153501981 4.547308e-01   15 74601592 74601895 304 + 0.106 0.218 1.237
ENSG00000179335 E003 0.1268540 0.0122610540 6.903571e-01   15 74603167 74603246 80 + 0.000 0.085 11.128
ENSG00000179335 E004 0.7508623 0.0143303959 1.653975e-01 4.350850e-01 15 74604933 74605581 649 + 0.106 0.319 1.974
ENSG00000179335 E005 0.7611206 0.0132303329 2.079485e-02 1.299602e-01 15 74605582 74605733 152 + 0.000 0.362 13.490
ENSG00000179335 E006 0.1187032 0.0118187588 4.168782e-01   15 74606243 74606365 123 + 0.106 0.000 -12.433
ENSG00000179335 E007 0.1176306 0.0117500788 4.168730e-01   15 74606366 74606415 50 + 0.106 0.000 -12.434
ENSG00000179335 E008 0.9876316 0.2197814689 7.126132e-01 8.839078e-01 15 74608277 74608371 95 + 0.262 0.319 0.390
ENSG00000179335 E009 0.8703479 0.2587631599 5.207847e-01 7.749697e-01 15 74608372 74608426 55 + 0.191 0.319 0.975
ENSG00000179335 E010 0.8802968 0.0142141449 9.990555e-02 3.302467e-01 15 74608427 74608727 301 + 0.106 0.362 2.237
ENSG00000179335 E011 0.0000000       15 74614829 74615049 221 +      
ENSG00000179335 E012 0.1268540 0.0122610540 6.903571e-01   15 74615796 74615835 40 + 0.000 0.085 11.128
ENSG00000179335 E013 0.1268540 0.0122610540 6.903571e-01   15 74615836 74615838 3 + 0.000 0.085 11.128
ENSG00000179335 E014 0.2438580 0.0162127689 8.446533e-01   15 74615839 74615841 3 + 0.106 0.085 -0.348
ENSG00000179335 E015 0.4898235 0.0157325261 8.019523e-01   15 74615842 74615843 2 + 0.191 0.157 -0.348
ENSG00000179335 E016 0.8430962 0.0124869075 1.421588e-01 4.011690e-01 15 74615844 74615854 11 + 0.377 0.157 -1.670
ENSG00000179335 E017 3.8829042 0.0625322575 7.117398e-02 2.703498e-01 15 74615855 74615871 17 + 0.814 0.557 -1.085
ENSG00000179335 E018 6.6868873 0.0023245044 1.638409e-02 1.112610e-01 15 74615872 74615891 20 + 1.005 0.761 -0.933
ENSG00000179335 E019 7.4391628 0.0021507669 6.205767e-02 2.502257e-01 15 74615892 74615898 7 + 1.017 0.836 -0.680
ENSG00000179335 E020 0.2441377 0.0162348783 8.448270e-01   15 74615899 74615914 16 + 0.106 0.085 -0.348
ENSG00000179335 E021 0.3712740 0.0168097228 7.507315e-01   15 74615915 74615949 35 + 0.106 0.157 0.652
ENSG00000179335 E022 0.1170040 0.0116658810 4.170101e-01   15 74619089 74619108 20 + 0.106 0.000 -12.434
ENSG00000179335 E023 0.1170040 0.0116658810 4.170101e-01   15 74619109 74619196 88 + 0.106 0.000 -12.434
ENSG00000179335 E024 21.8910750 0.0013812262 2.849246e-02 1.580851e-01 15 74619197 74619348 152 + 1.426 1.294 -0.461
ENSG00000179335 E025 0.3543453 0.0157599392 6.311415e-02   15 74619967 74620008 42 + 0.262 0.000 -13.881
ENSG00000179335 E026 34.6062211 0.0141570130 4.965842e-01 7.575599e-01 15 74620009 74620221 213 + 1.570 1.528 -0.142
ENSG00000179335 E027 11.7067871 0.0012295861 2.468259e-02 1.444164e-01 15 74620222 74620225 4 + 1.194 1.014 -0.649
ENSG00000179335 E028 35.3962964 0.0004168901 1.702639e-10 1.663589e-08 15 74620226 74621567 1342 + 1.325 1.670 1.184
ENSG00000179335 E029 13.1115774 0.0010143258 8.291227e-06 2.905647e-04 15 74621568 74622119 552 + 0.882 1.269 1.407
ENSG00000179335 E030 26.2874038 0.0006481510 1.328117e-02 9.660235e-02 15 74622120 74622216 97 + 1.504 1.368 -0.469
ENSG00000179335 E031 9.8785424 0.0238357472 2.331906e-04 4.746001e-03 15 74622217 74622493 277 + 0.734 1.166 1.629
ENSG00000179335 E032 22.8493705 0.0006124195 4.882068e-01 7.516040e-01 15 74622494 74622560 67 + 1.394 1.356 -0.130
ENSG00000179335 E033 2.9777855 0.0051691849 3.051529e-01 5.984686e-01 15 74623620 74624118 499 + 0.506 0.650 0.652
ENSG00000179335 E034 2.6475842 0.0109331189 7.082522e-04 1.144364e-02 15 74624119 74624346 228 + 0.191 0.709 2.900
ENSG00000179335 E035 4.6263195 0.0146433174 7.755674e-03 6.766330e-02 15 74624347 74624901 555 + 0.506 0.863 1.510
ENSG00000179335 E036 23.1061960 0.0056703547 7.185034e-01 8.867152e-01 15 74624902 74624969 68 + 1.389 1.368 -0.071
ENSG00000179335 E037 20.1596015 0.0133264945 7.685193e-01 9.105198e-01 15 74624970 74625018 49 + 1.331 1.312 -0.065
ENSG00000179335 E038 19.0196970 0.0150601933 5.016483e-01 7.615773e-01 15 74625802 74625852 51 + 1.325 1.274 -0.180
ENSG00000179335 E039 31.2715266 0.0005260642 2.272005e-01 5.155410e-01 15 74625853 74625968 116 + 1.537 1.478 -0.201
ENSG00000179335 E040 0.0000000       15 74626989 74627066 78 +      
ENSG00000179335 E041 27.5061712 0.0006129342 4.946006e-01 7.559605e-01 15 74627352 74627437 86 + 1.469 1.435 -0.115
ENSG00000179335 E042 12.0761884 0.0011632280 7.065830e-01 8.809823e-01 15 74627438 74627446 9 + 1.091 1.126 0.128
ENSG00000179335 E043 23.8436293 0.0006472968 6.454400e-01 8.499091e-01 15 74627539 74627616 78 + 1.403 1.380 -0.079
ENSG00000179335 E044 21.5654566 0.0059405599 1.721082e-01 4.448089e-01 15 74627617 74627668 52 + 1.398 1.308 -0.315
ENSG00000179335 E045 13.7772857 0.0010121934 1.059367e-02 8.342226e-02 15 74627970 74627983 14 + 1.265 1.074 -0.681
ENSG00000179335 E046 24.6546784 0.0006199132 2.111290e-03 2.662388e-02 15 74627984 74628052 69 + 1.497 1.321 -0.606
ENSG00000179335 E047 0.2530140 0.2725459316 4.043833e-01   15 74628592 74628593 2 + 0.000 0.156 11.511
ENSG00000179335 E048 0.3801504 0.0426986977 1.654336e-01   15 74628594 74628603 10 + 0.000 0.218 12.509
ENSG00000179335 E049 29.8212330 0.0004812252 3.129946e-01 6.063377e-01 15 74628604 74628683 80 + 1.512 1.462 -0.169
ENSG00000179335 E050 39.6162730 0.0021370750 9.887027e-01 1.000000e+00 15 74628942 74629032 91 + 1.601 1.605 0.013
ENSG00000179335 E051 6.6113763 0.0090407142 5.431905e-03 5.255909e-02 15 74629033 74629160 128 + 0.662 0.986 1.274
ENSG00000179335 E052 13.0257965 0.0022391266 1.924349e-02 1.239554e-01 15 74629161 74629706 546 + 1.017 1.215 0.715
ENSG00000179335 E053 72.7499812 0.0011468852 4.294282e-02 2.020985e-01 15 74629707 74630201 495 + 1.900 1.833 -0.226
ENSG00000179335 E054 0.2459655 0.0163169866 8.442664e-01   15 74635098 74635216 119 + 0.106 0.085 -0.348
ENSG00000179335 E055 32.3489556 0.0226886716 2.529235e-02 1.463357e-01 15 74635217 74639436 4220 + 1.398 1.588 0.651
ENSG00000179335 E056 9.7480265 0.0013946767 5.359092e-05 1.411315e-03 15 74639437 74645414 5978 + 0.755 1.153 1.496

Help

Please Click HERE to learn more details about the results from DEXseq.