ENSG00000179364

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000325438 ENSG00000179364 No_inf pgKDN_inf PACS2 protein_coding protein_coding 22.92897 33.08024 18.04479 1.151365 1.161391 -0.8740242 2.6250799 2.551425 1.716085 0.9522211 0.4737303 -0.5694433 0.12725833 0.078500 0.096950 0.018450 0.90377429 0.03278914 FALSE  
ENST00000547903 ENSG00000179364 No_inf pgKDN_inf PACS2 protein_coding retained_intron 22.92897 33.08024 18.04479 1.151365 1.161391 -0.8740242 4.1032031 5.158483 4.540706 0.8673609 0.5500542 -0.1836504 0.18080000 0.154375 0.249950 0.095575 0.55105646 0.03278914 FALSE  
ENST00000548796 ENSG00000179364 No_inf pgKDN_inf PACS2 protein_coding retained_intron 22.92897 33.08024 18.04479 1.151365 1.161391 -0.8740242 2.1760880 4.519196 0.741992 0.4071133 0.3321983 -2.5904658 0.08278333 0.137475 0.040225 -0.097250 0.21080316 0.03278914 FALSE  
ENST00000549030 ENSG00000179364 No_inf pgKDN_inf PACS2 protein_coding retained_intron 22.92897 33.08024 18.04479 1.151365 1.161391 -0.8740242 3.2594836 6.147377 1.208538 0.4949332 0.1998495 -2.3371646 0.13134167 0.185725 0.069375 -0.116350 0.16305406 0.03278914    
ENST00000550790 ENSG00000179364 No_inf pgKDN_inf PACS2 protein_coding retained_intron 22.92897 33.08024 18.04479 1.151365 1.161391 -0.8740242 0.6132453 1.671438 0.000000 0.6072919 0.0000000 -7.3935520 0.02045000 0.050750 0.000000 -0.050750 0.03278914 0.03278914 FALSE  
ENST00000552138 ENSG00000179364 No_inf pgKDN_inf PACS2 protein_coding retained_intron 22.92897 33.08024 18.04479 1.151365 1.161391 -0.8740242 1.6434700 1.885721 1.312516 1.1693542 0.7737866 -0.5194622 0.07517500 0.056000 0.073850 0.017850 1.00000000 0.03278914 FALSE  
ENST00000685365 ENSG00000179364 No_inf pgKDN_inf PACS2 protein_coding nonsense_mediated_decay 22.92897 33.08024 18.04479 1.151365 1.161391 -0.8740242 1.2970040 2.303613 0.000000 1.5346361 0.0000000 -7.8540040 0.05105833 0.065175 0.000000 -0.065175 0.61135168 0.03278914 TRUE  
ENST00000686461 ENSG00000179364 No_inf pgKDN_inf PACS2 protein_coding nonsense_mediated_decay 22.92897 33.08024 18.04479 1.151365 1.161391 -0.8740242 3.2121342 1.839430 6.179075 1.0640365 0.8608457 1.7426431 0.16932500 0.058825 0.347050 0.288225 0.09795793 0.03278914 FALSE  
ENST00000693530 ENSG00000179364 No_inf pgKDN_inf PACS2 protein_coding retained_intron 22.92897 33.08024 18.04479 1.151365 1.161391 -0.8740242 0.8767384 2.185422 0.000000 1.2629634 0.0000000 -7.7783544 0.03198333 0.067550 0.000000 -0.067550 0.62194816 0.03278914 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000179364 E001 0.0000000       14 105300563 105300979 417 +      
ENSG00000179364 E002 0.7348399 0.0146479152 5.624383e-01 8.023035e-01 14 105314415 105314747 333 + 0.285 0.199 -0.677
ENSG00000179364 E003 3.8276481 0.0041689432 9.549516e-01 9.890593e-01 14 105314748 105314879 132 + 0.673 0.670 -0.014
ENSG00000179364 E004 1.2333789 0.0097617793 9.091600e-01 9.711945e-01 14 105314880 105314882 3 + 0.350 0.335 -0.092
ENSG00000179364 E005 1.2418771 0.0101965694 5.897803e-01 8.183486e-01 14 105314883 105314886 4 + 0.285 0.372 0.546
ENSG00000179364 E006 1.1242465 0.0108490779 3.091342e-01 6.024913e-01 14 105314887 105314887 1 + 0.209 0.372 1.131
ENSG00000179364 E007 0.9977394 0.0120870430 4.324281e-01 7.098045e-01 14 105314888 105314889 2 + 0.209 0.335 0.908
ENSG00000179364 E008 1.7339030 0.0095453204 8.481450e-01 9.462614e-01 14 105314890 105314975 86 + 0.406 0.438 0.171
ENSG00000179364 E009 1.8672060 0.0076915441 3.497062e-01 6.399488e-01 14 105314976 105315037 62 + 0.350 0.495 0.783
ENSG00000179364 E010 0.1268540 0.0123457045 9.276012e-01   14 105318168 105318260 93 + 0.000 0.077 9.728
ENSG00000179364 E011 0.2539903 0.0160203493 4.580927e-01   14 105336425 105336658 234 + 0.000 0.142 10.671
ENSG00000179364 E012 3.5826966 0.0038328997 9.746185e-01 9.954114e-01 14 105348493 105348536 44 + 0.644 0.652 0.034
ENSG00000179364 E013 5.6306355 0.0119712417 1.251177e-01 3.749727e-01 14 105348537 105348580 44 + 0.909 0.737 -0.677
ENSG00000179364 E014 0.0000000       14 105348581 105348746 166 +      
ENSG00000179364 E015 11.2246232 0.0053114451 2.758328e-03 3.242946e-02 14 105352378 105352467 90 + 1.217 0.961 -0.928
ENSG00000179364 E016 0.0000000       14 105355049 105355051 3 +      
ENSG00000179364 E017 10.9304618 0.0012170783 1.273423e-05 4.200662e-04 14 105355052 105355177 126 + 1.256 0.891 -1.329
ENSG00000179364 E018 0.7434642 0.0138826980 8.039205e-01 9.271630e-01 14 105355178 105356191 1014 + 0.209 0.249 0.323
ENSG00000179364 E019 0.0000000       14 105367041 105367212 172 +      
ENSG00000179364 E020 14.1248943 0.0167765842 1.910758e-01 4.704466e-01 14 105367213 105367375 163 + 1.233 1.120 -0.400
ENSG00000179364 E021 4.1642138 0.0033950054 1.682536e-01 4.394048e-01 14 105368074 105368084 11 + 0.797 0.633 -0.677
ENSG00000179364 E022 8.4608263 0.0016422040 1.077213e-01 3.441238e-01 14 105368085 105368147 63 + 1.050 0.901 -0.551
ENSG00000179364 E023 16.2754258 0.0009703550 4.606543e-03 4.671855e-02 14 105368459 105368515 57 + 1.337 1.139 -0.699
ENSG00000179364 E024 12.9772124 0.0010944723 1.424617e-02 1.014595e-01 14 105368516 105368539 24 + 1.241 1.052 -0.677
ENSG00000179364 E025 16.3667618 0.0008973799 5.557356e-04 9.488143e-03 14 105369841 105369900 60 + 1.361 1.120 -0.849
ENSG00000179364 E026 1.2533601 0.1528005578 3.148286e-01 6.076723e-01 14 105369901 105370158 258 + 0.209 0.406 1.324
ENSG00000179364 E027 18.8672103 0.0015658659 5.708201e-03 5.445103e-02 14 105376768 105376925 158 + 1.390 1.207 -0.639
ENSG00000179364 E028 13.2005869 0.0011178427 8.295255e-01 9.382445e-01 14 105379739 105379829 91 + 1.146 1.133 -0.047
ENSG00000179364 E029 11.5265326 0.0058702019 1.114235e-01 3.505146e-01 14 105380080 105380154 75 + 1.165 1.029 -0.492
ENSG00000179364 E030 15.2404443 0.0010298087 1.170029e-01 3.610536e-01 14 105380957 105381099 143 + 1.263 1.151 -0.397
ENSG00000179364 E031 5.8289380 0.0170684268 5.799780e-01 8.125237e-01 14 105381914 105381923 10 + 0.775 0.845 0.277
ENSG00000179364 E032 17.7343659 0.0018846413 3.170936e-01 6.098257e-01 14 105381924 105382046 123 + 1.298 1.232 -0.233
ENSG00000179364 E033 0.9889891 0.0117420133 9.657899e-01 9.929839e-01 14 105382047 105382058 12 + 0.285 0.294 0.060
ENSG00000179364 E034 16.5427650 0.0035727881 1.615888e-02 1.104299e-01 14 105382477 105382581 105 + 1.331 1.157 -0.613
ENSG00000179364 E035 18.6457823 0.0008227833 1.422889e-02 1.013766e-01 14 105382807 105382913 107 + 1.373 1.212 -0.563
ENSG00000179364 E036 1.5143379 0.0090293014 1.907441e-02 1.231360e-01 14 105383119 105383358 240 + 0.117 0.495 2.783
ENSG00000179364 E037 9.5536199 0.0013988918 3.598085e-02 1.819783e-01 14 105383359 105383377 19 + 1.116 0.932 -0.677
ENSG00000179364 E038 20.8154873 0.0006479939 3.132197e-01 6.064074e-01 14 105383378 105383513 136 + 1.361 1.300 -0.212
ENSG00000179364 E039 2.0051350 0.0069112339 9.424450e-02 3.195237e-01 14 105383514 105384352 839 + 0.285 0.546 1.439
ENSG00000179364 E040 16.4305124 0.0008380418 9.785874e-01 9.970891e-01 14 105384353 105384463 111 + 1.225 1.227 0.008
ENSG00000179364 E041 7.6457695 0.0258313900 5.907710e-01 8.188681e-01 14 105384879 105384883 5 + 0.957 0.901 -0.208
ENSG00000179364 E042 20.4165316 0.0034805369 1.481552e-01 4.098586e-01 14 105384884 105384987 104 + 1.373 1.279 -0.328
ENSG00000179364 E043 2.6389011 0.0053456361 1.620265e-02 1.106030e-01 14 105385685 105385717 33 + 0.285 0.652 1.908
ENSG00000179364 E044 20.2490067 0.0035174778 8.608416e-12 9.836574e-10 14 105388622 105389452 831 + 0.875 1.449 2.060
ENSG00000179364 E045 11.0246780 0.0013267544 4.784742e-05 1.284848e-03 14 105389453 105389960 508 + 0.775 1.174 1.493
ENSG00000179364 E046 14.5620790 0.0011279884 8.676954e-01 9.545723e-01 14 105389961 105390003 43 + 1.183 1.174 -0.030
ENSG00000179364 E047 10.8234219 0.0245215344 2.623304e-06 1.072688e-04 14 105390237 105391206 970 + 0.612 1.196 2.249
ENSG00000179364 E048 14.7521486 0.0013322551 1.883812e-01 4.667257e-01 14 105391207 105391249 43 + 1.241 1.145 -0.339
ENSG00000179364 E049 8.4088459 0.0137954023 3.278617e-04 6.250580e-03 14 105391250 105391458 209 + 0.644 1.073 1.671
ENSG00000179364 E050 3.7531970 0.0041855080 3.309680e-02 1.728291e-01 14 105391459 105391499 41 + 0.456 0.752 1.323
ENSG00000179364 E051 6.5224731 0.0023362625 1.102012e-03 1.614886e-02 14 105391500 105391630 131 + 0.578 0.970 1.580
ENSG00000179364 E052 25.3156939 0.0005602244 9.566670e-01 9.897163e-01 14 105391631 105391766 136 + 1.400 1.408 0.026
ENSG00000179364 E053 1.1256284 0.0108466049 3.084882e-01 6.017143e-01 14 105391767 105392004 238 + 0.209 0.372 1.131
ENSG00000179364 E054 2.6592604 0.0739311676 1.516033e-03 2.066879e-02 14 105392005 105392618 614 + 0.117 0.688 3.645
ENSG00000179364 E055 26.7755888 0.0005752682 5.721850e-01 8.082824e-01 14 105392619 105392760 142 + 1.446 1.418 -0.097
ENSG00000179364 E056 19.7327462 0.0011419186 5.396893e-01 7.880438e-01 14 105392761 105392845 85 + 1.325 1.288 -0.129
ENSG00000179364 E057 26.4219641 0.0005820262 8.671575e-01 9.542307e-01 14 105393222 105393335 114 + 1.426 1.421 -0.018
ENSG00000179364 E058 0.7615290 0.0132956428 3.948392e-02 1.926109e-01 14 105393336 105393543 208 + 0.000 0.335 12.135
ENSG00000179364 E059 149.2891540 0.0001958028 2.124593e-07 1.147183e-05 14 105394554 105398147 3594 + 2.076 2.204 0.427

Help

Please Click HERE to learn more details about the results from DEXseq.