ENSG00000179456

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000358704 ENSG00000179456 No_inf pgKDN_inf ZBTB18 protein_coding protein_coding 10.18752 15.05541 8.570347 0.5126366 0.2523404 -0.8121317 2.3397391 2.7916137 3.1214021 1.1987644 1.2229033 0.1605507 0.23977500 0.188975 0.372975 0.184000 8.342894e-01 4.750144e-05 FALSE TRUE
ENST00000622512 ENSG00000179456 No_inf pgKDN_inf ZBTB18 protein_coding protein_coding 10.18752 15.05541 8.570347 0.5126366 0.2523404 -0.8121317 2.0683455 3.1394602 0.2247386 1.0554950 0.2247386 -3.7459775 0.21634167 0.212200 0.025825 -0.186375 3.555602e-01 4.750144e-05 FALSE TRUE
ENST00000696615 ENSG00000179456 No_inf pgKDN_inf ZBTB18 protein_coding protein_coding 10.18752 15.05541 8.570347 0.5126366 0.2523404 -0.8121317 1.6021294 0.7176626 2.7266616 0.7176626 1.6195025 1.9110754 0.18715833 0.051600 0.307025 0.255425 6.995037e-01 4.750144e-05 FALSE TRUE
ENST00000696616 ENSG00000179456 No_inf pgKDN_inf ZBTB18 protein_coding protein_coding 10.18752 15.05541 8.570347 0.5126366 0.2523404 -0.8121317 0.9940287 1.3325997 0.5476673 1.3325997 0.5476673 -1.2675526 0.10330000 0.084325 0.070000 -0.014325 9.715728e-01 4.750144e-05 FALSE TRUE
ENST00000696617 ENSG00000179456 No_inf pgKDN_inf ZBTB18 protein_coding protein_coding 10.18752 15.05541 8.570347 0.5126366 0.2523404 -0.8121317 1.1567808 3.4703424 0.0000000 0.4750647 0.0000000 -8.4430854 0.07748333 0.232450 0.000000 -0.232450 4.750144e-05 4.750144e-05 FALSE TRUE
MSTRG.2939.2 ENSG00000179456 No_inf pgKDN_inf ZBTB18 protein_coding   10.18752 15.05541 8.570347 0.5126366 0.2523404 -0.8121317 2.0265000 3.6037288 1.9498777 1.5425200 1.9498777 -0.8827246 0.17596667 0.230475 0.224175 -0.006300 5.605031e-01 4.750144e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000179456 E001 0.1265070 0.0123167248 1.000000000   1 244048547 244048586 40 + 0.000 0.069 7.981
ENSG00000179456 E002 0.2373413 0.0161297606 0.077660451   1 244048906 244048938 33 + 0.230 0.000 -12.516
ENSG00000179456 E003 1.1080094 0.0123428920 0.469067341 0.73708621 1 244048939 244048993 55 + 0.380 0.269 -0.706
ENSG00000179456 E004 0.8498655 0.2350264605 0.290178735 0.58380611 1 244049799 244049921 123 + 0.380 0.180 -1.442
ENSG00000179456 E005 1.2329357 0.0107192299 0.632825485 0.84277753 1 244051283 244051358 76 + 0.380 0.307 -0.443
ENSG00000179456 E006 1.8576993 0.0077174552 0.960105755 0.99083719 1 244051359 244051444 86 + 0.439 0.434 -0.028
ENSG00000179456 E007 0.7531908 0.0141755057 0.390025579 0.67551791 1 244052236 244052277 42 + 0.130 0.269 1.294
ENSG00000179456 E008 3.0271111 0.0048941433 0.004534593 0.04626726 1 244053100 244053170 71 + 0.230 0.679 2.431
ENSG00000179456 E009 1.7770483 0.0075841594 0.002031136 0.02583663 1 244053171 244053200 30 + 0.000 0.531 12.734
ENSG00000179456 E010 33.6015670 0.0005377958 0.057085198 0.23881923 1 244053788 244054475 688 + 1.568 1.477 -0.314
ENSG00000179456 E011 5.1215485 0.0043297543 0.130779839 0.38353287 1 244054476 244054587 112 + 0.618 0.812 0.802
ENSG00000179456 E012 192.8892672 0.0001478920 0.740795911 0.89714860 1 244054588 244057476 2889 + 2.250 2.257 0.024

Help

Please Click HERE to learn more details about the results from DEXseq.