ENSG00000179526

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000359551 ENSG00000179526 No_inf pgKDN_inf SHARPIN protein_coding nonsense_mediated_decay 51.71655 64.76522 39.42443 3.847197 2.07836 -0.715986 3.176931 2.806445 3.318360 1.6418307 1.9449165 0.2409363 0.06362500 0.042225 0.081775 0.039550 0.9570747671 0.0005976964 TRUE TRUE
ENST00000398712 ENSG00000179526 No_inf pgKDN_inf SHARPIN protein_coding protein_coding 51.71655 64.76522 39.42443 3.847197 2.07836 -0.715986 22.210938 19.427763 21.616173 0.8885007 0.9991752 0.1539162 0.45283333 0.301350 0.550425 0.249075 0.0005976964 0.0005976964 FALSE TRUE
ENST00000530216 ENSG00000179526 No_inf pgKDN_inf SHARPIN protein_coding retained_intron 51.71655 64.76522 39.42443 3.847197 2.07836 -0.715986 6.975875 14.233349 2.035857 3.8108813 1.1821938 -2.7995115 0.11857500 0.216850 0.048150 -0.168700 0.2023412703 0.0005976964   FALSE
ENST00000532536 ENSG00000179526 No_inf pgKDN_inf SHARPIN protein_coding protein_coding 51.71655 64.76522 39.42443 3.847197 2.07836 -0.715986 3.795467 5.749662 3.799582 3.5263136 1.2480449 -0.5963514 0.07135000 0.080975 0.096875 0.015900 0.8400510768 0.0005976964 FALSE FALSE
MSTRG.28354.2 ENSG00000179526 No_inf pgKDN_inf SHARPIN protein_coding   51.71655 64.76522 39.42443 3.847197 2.07836 -0.715986 2.105285 3.996207 0.000000 1.4736761 0.0000000 -8.6460931 0.03596667 0.063525 0.000000 -0.063525 0.0030313426 0.0005976964 FALSE FALSE
MSTRG.28354.9 ENSG00000179526 No_inf pgKDN_inf SHARPIN protein_coding   51.71655 64.76522 39.42443 3.847197 2.07836 -0.715986 4.274173 6.372847 2.152384 2.4179000 2.1523842 -1.5615771 0.07890000 0.104675 0.049875 -0.054800 0.4169062624 0.0005976964 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000179526 E001 0.2545247 0.2643485088 4.976224e-01   8 144097998 144098078 81 - 0.000 0.145 10.088
ENSG00000179526 E002 0.6337937 0.1653816157 9.170332e-02 0.314473064 8 144098473 144098632 160 - 0.000 0.298 11.414
ENSG00000179526 E003 0.0000000       8 144098633 144098636 4 -      
ENSG00000179526 E004 0.5977849 0.5989599219 3.613289e-01 0.650810059 8 144098637 144098639 3 - 0.345 0.078 -2.615
ENSG00000179526 E005 0.7246389 0.4532836861 5.215166e-01 0.775364305 8 144098640 144098640 1 - 0.345 0.145 -1.616
ENSG00000179526 E006 0.9619801 0.0890081091 6.397124e-02 0.254741931 8 144098641 144098645 5 - 0.450 0.145 -2.202
ENSG00000179526 E007 1.0789841 0.0191207114 2.142239e-02 0.132529818 8 144098646 144098646 1 - 0.494 0.145 -2.425
ENSG00000179526 E008 16.0919129 0.0009195207 1.353771e-01 0.391027971 8 144098647 144098788 142 - 1.283 1.177 -0.375
ENSG00000179526 E009 1.8400163 0.0091198891 5.729006e-01 0.808595795 8 144098789 144098865 77 - 0.494 0.412 -0.425
ENSG00000179526 E010 34.3136648 0.0004618732 1.024932e-01 0.334751416 8 144098866 144098994 129 - 1.583 1.503 -0.275
ENSG00000179526 E011 23.3115617 0.0006706309 8.150603e-01 0.932395521 8 144099081 144099121 41 - 1.381 1.368 -0.045
ENSG00000179526 E012 27.7585569 0.0005567295 8.495143e-01 0.946470774 8 144099122 144099199 78 - 1.452 1.442 -0.033
ENSG00000179526 E013 11.0003655 0.0013279690 6.543513e-01 0.854874487 8 144099200 144099205 6 - 1.042 1.082 0.145
ENSG00000179526 E014 2.6385849 0.0056071096 1.223941e-02 0.091564598 8 144099250 144099276 27 - 0.281 0.659 1.967
ENSG00000179526 E015 20.0532641 0.0031662027 2.907061e-01 0.584228688 8 144099277 144099290 14 - 1.262 1.337 0.264
ENSG00000179526 E016 20.9430292 0.0007952756 1.260446e-01 0.376395980 8 144099291 144099300 10 - 1.262 1.364 0.357
ENSG00000179526 E017 49.4787220 0.0003376023 4.872269e-03 0.048681168 8 144099301 144099430 130 - 1.610 1.732 0.415
ENSG00000179526 E018 1.3858816 0.0096409798 2.480115e-02 0.144788253 8 144099431 144099509 79 - 0.115 0.474 2.704
ENSG00000179526 E019 19.5204240 0.0007901092 8.385103e-01 0.942106797 8 144099510 144099518 9 - 1.290 1.305 0.052
ENSG00000179526 E020 39.9866626 0.0003710825 8.737459e-01 0.956917217 8 144099519 144099618 100 - 1.603 1.597 -0.021
ENSG00000179526 E021 48.8530748 0.0003666848 7.482407e-01 0.900639679 8 144099703 144099844 142 - 1.692 1.680 -0.042
ENSG00000179526 E022 40.0109438 0.0036275370 7.763380e-01 0.914130928 8 144099929 144100065 137 - 1.590 1.606 0.053
ENSG00000179526 E023 16.1509056 0.0010429603 6.691450e-01 0.862332230 8 144100066 144100069 4 - 1.240 1.210 -0.106
ENSG00000179526 E024 2.5228395 0.0055826961 3.362329e-03 0.037623206 8 144100743 144100842 100 - 0.206 0.659 2.552
ENSG00000179526 E025 3.6202693 0.0051793227 8.629060e-02 0.304361874 8 144102642 144102816 175 - 0.494 0.728 1.035
ENSG00000179526 E026 3.7388496 0.0315299917 1.843805e-01 0.461572201 8 144102817 144103050 234 - 0.535 0.728 0.842
ENSG00000179526 E027 25.2140658 0.0006666674 6.255591e-01 0.838941915 8 144103051 144103116 66 - 1.386 1.417 0.104
ENSG00000179526 E028 28.8176691 0.0005948910 3.551495e-01 0.644893656 8 144103117 144103225 109 - 1.492 1.442 -0.170
ENSG00000179526 E029 27.2663936 0.0005016195 6.056211e-05 0.001556891 8 144103553 144103846 294 - 1.562 1.341 -0.760
ENSG00000179526 E030 8.6000988 0.0017331580 2.861931e-01 0.579818125 8 144103847 144104024 178 - 1.029 0.930 -0.370
ENSG00000179526 E031 13.6238251 0.0011171099 2.948288e-01 0.588087545 8 144104025 144104269 245 - 1.098 1.183 0.304
ENSG00000179526 E032 0.0000000       8 144105727 144105862 136 -      
ENSG00000179526 E033 0.0000000       8 144108018 144108124 107 -      

Help

Please Click HERE to learn more details about the results from DEXseq.