ENSG00000180098

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373830 ENSG00000180098 No_inf pgKDN_inf TRNAU1AP protein_coding protein_coding 19.31935 20.14867 18.9166 2.583744 0.9775802 -0.09098513 6.4678533 6.155492 5.91846238 0.5105514 0.30170323 -0.0565581 0.34407500 0.327375 0.316300 -0.011075 1.00000000 0.02159329 FALSE  
ENST00000464093 ENSG00000180098 No_inf pgKDN_inf TRNAU1AP protein_coding protein_coding_CDS_not_defined 19.31935 20.14867 18.9166 2.583744 0.9775802 -0.09098513 0.5425935 1.432290 0.04873926 0.3637320 0.04873926 -4.6178923 0.02840833 0.075325 0.002525 -0.072800 0.02159329 0.02159329    
ENST00000495215 ENSG00000180098 No_inf pgKDN_inf TRNAU1AP protein_coding protein_coding_CDS_not_defined 19.31935 20.14867 18.9166 2.583744 0.9775802 -0.09098513 9.1771713 7.617495 10.02413645 2.9561011 0.98395602 0.3956353 0.46675000 0.348825 0.528150 0.179325 0.77231425 0.02159329 FALSE  
MSTRG.567.2 ENSG00000180098 No_inf pgKDN_inf TRNAU1AP protein_coding   19.31935 20.14867 18.9166 2.583744 0.9775802 -0.09098513 1.0879649 2.089021 0.98027754 0.5119438 0.67974577 -1.0838115 0.05690000 0.111150 0.049750 -0.061400 0.60159180 0.02159329 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000180098 E001 0.1187032 0.0119708011 0.425284473   1 28553085 28553086 2 + 0.105 0.000 -10.572
ENSG00000180098 E002 0.1187032 0.0119708011 0.425284473   1 28553087 28553096 10 + 0.105 0.000 -11.594
ENSG00000180098 E003 0.6068275 0.0160330799 0.484816260 0.74880153 1 28553097 28553098 2 + 0.261 0.157 -0.918
ENSG00000180098 E004 1.2167971 0.0107005429 0.323759654 0.61637359 1 28553099 28553105 7 + 0.423 0.272 -0.918
ENSG00000180098 E005 1.3436511 0.0132256086 0.501785414 0.76158553 1 28553106 28553106 1 + 0.423 0.320 -0.596
ENSG00000180098 E006 3.3107078 0.0044711567 0.688865948 0.87188767 1 28553107 28553137 31 + 0.660 0.608 -0.226
ENSG00000180098 E007 0.2356421 0.0156703544 0.172919224   1 28553138 28553232 95 + 0.190 0.000 -12.566
ENSG00000180098 E008 0.0000000       1 28553233 28553246 14 +      
ENSG00000180098 E009 0.3641952 0.0166859134 0.450406891   1 28553247 28553307 61 + 0.190 0.086 -1.333
ENSG00000180098 E010 0.9905934 0.0129656724 0.701314356 0.87831588 1 28553308 28553639 332 + 0.261 0.320 0.404
ENSG00000180098 E011 5.6424020 0.0027340827 0.628186052 0.84027149 1 28553640 28553671 32 + 0.848 0.795 -0.208
ENSG00000180098 E012 10.4118949 0.0014267870 0.330476935 0.62297519 1 28553672 28553737 66 + 1.098 1.016 -0.299
ENSG00000180098 E013 0.0000000       1 28553738 28554048 311 +      
ENSG00000180098 E014 13.9054811 0.0014071188 0.014961676 0.10485227 1 28560633 28560732 100 + 1.263 1.084 -0.638
ENSG00000180098 E015 0.9984947 0.0131058412 0.262620095 0.55543517 1 28560733 28560867 135 + 0.190 0.363 1.252
ENSG00000180098 E016 2.1117483 0.0080288442 0.212860652 0.49802301 1 28560868 28561112 245 + 0.375 0.558 0.930
ENSG00000180098 E017 2.4479063 0.0063801617 0.609935219 0.83032016 1 28561113 28561260 148 + 0.574 0.503 -0.333
ENSG00000180098 E018 0.0000000       1 28561261 28561345 85 +      
ENSG00000180098 E019 12.7537370 0.0115164139 0.465444019 0.73447474 1 28561346 28561398 53 + 1.168 1.106 -0.222
ENSG00000180098 E020 19.4099709 0.0008278194 0.048428849 0.21662285 1 28564703 28564834 132 + 1.229 1.354 0.438
ENSG00000180098 E021 4.8791497 0.0431013759 0.007582296 0.06661403 1 28564835 28565790 956 + 0.505 0.890 1.621
ENSG00000180098 E022 18.4991795 0.0009287331 0.345148012 0.63617829 1 28567294 28567413 120 + 1.249 1.310 0.212
ENSG00000180098 E023 20.4271414 0.0007002132 0.802305421 0.92638199 1 28571176 28571338 163 + 1.318 1.332 0.051
ENSG00000180098 E024 7.1357669 0.0022490414 0.856265223 0.94950057 1 28571867 28571900 34 + 0.896 0.914 0.067
ENSG00000180098 E025 1.2603175 0.0107933355 0.018721611 0.12142739 1 28574589 28574718 130 + 0.105 0.472 2.837
ENSG00000180098 E026 0.3810317 0.0289957786 0.157764405   1 28574719 28574759 41 + 0.000 0.219 12.220
ENSG00000180098 E027 18.6289746 0.0113513169 0.305675780 0.59896585 1 28577500 28578545 1046 + 1.329 1.256 -0.257

Help

Please Click HERE to learn more details about the results from DEXseq.