ENSG00000180104

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000315013 ENSG00000180104 No_inf pgKDN_inf EXOC3 protein_coding protein_coding 55.48152 67.91299 50.18644 0.7877168 1.542159 -0.436315 24.795543 29.0142709 24.593794 4.1211057 2.977132 -0.2383790 0.45580833 0.429100 0.495800 0.066700 0.83911371 0.01274901 FALSE TRUE
ENST00000509294 ENSG00000180104 No_inf pgKDN_inf EXOC3 protein_coding protein_coding_CDS_not_defined 55.48152 67.91299 50.18644 0.7877168 1.542159 -0.436315 5.349367 7.6100511 5.139086 0.8358819 1.444797 -0.5654844 0.09187500 0.111725 0.101400 -0.010325 0.89658920 0.01274901 FALSE FALSE
ENST00000511015 ENSG00000180104 No_inf pgKDN_inf EXOC3 protein_coding retained_intron 55.48152 67.91299 50.18644 0.7877168 1.542159 -0.436315 4.520413 7.6847015 2.021142 0.4384367 0.583697 -1.9215744 0.07923333 0.113325 0.041125 -0.072200 0.17962992 0.01274901 FALSE TRUE
ENST00000512944 ENSG00000180104 No_inf pgKDN_inf EXOC3 protein_coding protein_coding 55.48152 67.91299 50.18644 0.7877168 1.542159 -0.436315 6.471042 0.9810894 9.648499 0.9810894 3.110742 3.2847119 0.12619167 0.014650 0.187375 0.172725 0.01274901 0.01274901 FALSE TRUE
MSTRG.22644.12 ENSG00000180104 No_inf pgKDN_inf EXOC3 protein_coding   55.48152 67.91299 50.18644 0.7877168 1.542159 -0.436315 3.039078 2.8953368 2.077244 2.0900087 1.323527 -0.4771063 0.05624167 0.041625 0.041300 -0.000325 1.00000000 0.01274901 TRUE TRUE
MSTRG.22644.5 ENSG00000180104 No_inf pgKDN_inf EXOC3 protein_coding   55.48152 67.91299 50.18644 0.7877168 1.542159 -0.436315 1.348983 4.0469497 0.000000 2.8376877 0.000000 -8.6642516 0.01940833 0.058225 0.000000 -0.058225 0.54806289 0.01274901 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000180104 E001 0.0000000       5 442811 442869 59 +      
ENSG00000180104 E002 0.1176306 0.0117626883 4.216970e-01   5 443175 443175 1 + 0.106 0.000 -10.207
ENSG00000180104 E003 0.1176306 0.0117626883 4.216970e-01   5 443176 443186 11 + 0.106 0.000 -12.741
ENSG00000180104 E004 0.3634051 0.0166806959 4.452779e-01   5 443187 443232 46 + 0.191 0.085 -1.354
ENSG00000180104 E005 0.6175214 0.0143212575 8.573282e-01 0.9500347484 5 443233 443247 15 + 0.191 0.217 0.231
ENSG00000180104 E006 0.8640860 0.0153292625 9.517729e-01 0.9878643841 5 443248 443267 20 + 0.263 0.271 0.061
ENSG00000180104 E007 2.6728742 0.0130635530 7.455658e-02 0.2783948114 5 443268 443290 23 + 0.688 0.436 -1.162
ENSG00000180104 E008 0.3806233 0.0158716512 1.583195e-01   5 444926 445036 111 + 0.000 0.217 12.892
ENSG00000180104 E009 0.3625236 0.2073310087 4.977512e-01   5 445037 445064 28 + 0.191 0.085 -1.354
ENSG00000180104 E010 0.2459655 0.0164055637 8.522169e-01   5 446149 446149 1 + 0.106 0.085 -0.354
ENSG00000180104 E011 3.2894531 0.0175679877 1.354135e-01 0.3910722815 5 446150 446154 5 + 0.735 0.529 -0.895
ENSG00000180104 E012 28.4029992 0.0093662045 7.317034e-02 0.2748742261 5 446155 446349 195 + 1.531 1.406 -0.429
ENSG00000180104 E013 0.9889567 0.0579358345 7.189206e-01 0.8868074864 5 447018 447430 413 + 0.263 0.319 0.382
ENSG00000180104 E014 0.6079236 0.0228102047 4.790945e-01 0.7449984491 5 447431 447532 102 + 0.263 0.156 -0.939
ENSG00000180104 E015 22.8215444 0.0240374666 3.074790e-02 0.1650157524 5 447533 447648 116 + 1.470 1.283 -0.649
ENSG00000180104 E016 28.2453857 0.0010887663 8.165228e-03 0.0700578096 5 447649 447752 104 + 1.541 1.391 -0.517
ENSG00000180104 E017 0.4731135 0.1835320948 4.419672e-02   5 453266 453369 104 + 0.324 0.000 -13.861
ENSG00000180104 E018 17.2745720 0.0098981835 1.880211e-01 0.4662873815 5 453370 453396 27 + 1.315 1.208 -0.375
ENSG00000180104 E019 141.3033004 0.0001511735 3.486272e-02 0.1785646638 5 453397 454051 655 + 2.177 2.125 -0.176
ENSG00000180104 E020 37.6210243 0.0142714163 2.115800e-02 0.1315387496 5 456889 457005 117 + 1.669 1.505 -0.560
ENSG00000180104 E021 14.8702867 0.0324134668 5.810369e-02 0.2412443925 5 457006 457006 1 + 1.303 1.096 -0.735
ENSG00000180104 E022 3.9875181 0.0036587565 2.723961e-02 0.1534727762 5 457007 457899 893 + 0.507 0.792 1.231
ENSG00000180104 E023 50.2821788 0.0002906875 2.532393e-03 0.0304191767 5 457900 458025 126 + 1.774 1.646 -0.431
ENSG00000180104 E024 30.5960796 0.0017028732 6.706597e-01 0.8631546411 5 459359 459415 57 + 1.509 1.483 -0.087
ENSG00000180104 E025 25.2136281 0.0132214578 9.947422e-01 1.0000000000 5 459416 459459 44 + 1.413 1.413 0.000
ENSG00000180104 E026 3.7649376 0.0762301585 1.063097e-02 0.0836061076 5 459460 459580 121 + 0.377 0.807 1.967
ENSG00000180104 E027 10.5056618 0.0061132569 1.272036e-05 0.0004200662 5 461630 461959 330 + 0.756 1.190 1.624
ENSG00000180104 E028 47.0866937 0.0003321018 2.887489e-01 0.5822356045 5 461960 462070 111 + 1.651 1.695 0.149
ENSG00000180104 E029 47.9999071 0.0003233950 7.042690e-01 0.8798101797 5 462157 462307 151 + 1.677 1.691 0.048
ENSG00000180104 E030 3.4895017 0.3637559705 4.064456e-01 0.6891304136 5 462308 462529 222 + 0.468 0.744 1.232
ENSG00000180104 E031 54.8091019 0.0003845555 5.700185e-01 0.8068195138 5 464290 464412 123 + 1.729 1.750 0.070
ENSG00000180104 E032 11.3784266 0.0012173572 4.161993e-06 0.0001604007 5 464413 464788 376 + 0.796 1.220 1.568
ENSG00000180104 E033 7.9180161 0.0017592613 1.927308e-01 0.4725526967 5 464789 465110 322 + 0.867 0.995 0.480
ENSG00000180104 E034 86.3431160 0.0001927296 9.369658e-01 0.9820115012 5 465111 465272 162 + 1.938 1.934 -0.016
ENSG00000180104 E035 75.1388893 0.0002407087 2.580027e-01 0.5502220983 5 465718 465845 128 + 1.855 1.891 0.123
ENSG00000180104 E036 0.6348960 0.0142330921 3.892492e-02 0.1909940798 5 465846 466078 233 + 0.000 0.319 13.588
ENSG00000180104 E037 143.5722183 0.0018258954 1.597571e-03 0.0214764204 5 466727 467562 836 + 2.102 2.190 0.294
ENSG00000180104 E038 3.7355468 0.0038227217 5.197066e-02 0.2263159624 5 467563 468276 714 + 0.507 0.761 1.105
ENSG00000180104 E039 4.0666651 0.0098884810 6.045026e-01 0.8274517774 5 468277 468609 333 + 0.662 0.727 0.267
ENSG00000180104 E040 6.2210637 0.0022338119 2.074877e-02 0.1298067822 5 468610 468869 260 + 0.688 0.944 1.008
ENSG00000180104 E041 4.9637609 0.0028526538 1.411337e-01 0.3997336223 5 468870 468942 73 + 0.663 0.835 0.700
ENSG00000180104 E042 5.4779742 0.0028847674 2.343765e-02 0.1399055317 5 469790 469855 66 + 0.636 0.899 1.061
ENSG00000180104 E043 5.7003040 0.0026347491 2.070943e-01 0.4906805735 5 469856 469987 132 + 0.735 0.875 0.553
ENSG00000180104 E044 0.0000000       5 470946 471098 153 +      
ENSG00000180104 E045 0.0000000       5 471099 471122 24 +      
ENSG00000180104 E046 0.0000000       5 471123 471937 815 +      

Help

Please Click HERE to learn more details about the results from DEXseq.