ENSG00000180304

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000326005 ENSG00000180304 No_inf pgKDN_inf OAZ2 protein_coding protein_coding 51.71937 42.87975 55.8951 0.72344 0.4478022 0.3823471 49.21459 39.52555 54.67477 0.4884042 0.24532 0.4679887 0.94945 0.92245 0.978275 0.055825 0.0258075 0.0258075    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000180304 E001 0.0000000       15 64687573 64687575 3 -      
ENSG00000180304 E002 0.6190673 0.1705076086 5.706485e-01 8.070209e-01 15 64687576 64687603 28 - 0.161 0.255 0.828
ENSG00000180304 E003 208.1494512 0.0001787995 1.364544e-07 7.730601e-06 15 64687604 64688484 881 - 2.271 2.368 0.321
ENSG00000180304 E004 103.9399430 0.0002303659 4.804138e-02 2.156640e-01 15 64688485 64688834 350 - 2.044 1.993 -0.169
ENSG00000180304 E005 41.5992404 0.0004374783 4.092492e-02 1.963217e-01 15 64689084 64689169 86 - 1.669 1.580 -0.303
ENSG00000180304 E006 0.1271363 0.0123410362 4.586952e-01   15 64690167 64690373 207 - 0.000 0.103 11.270
ENSG00000180304 E007 28.9394132 0.0032120418 7.431535e-02 2.779174e-01 15 64690374 64690419 46 - 1.521 1.420 -0.347
ENSG00000180304 E008 27.2631190 0.0005427675 2.163280e-01 5.024086e-01 15 64690420 64690444 25 - 1.481 1.415 -0.225
ENSG00000180304 E009 23.0262444 0.0006002822 4.614677e-01 7.321858e-01 15 64690445 64690460 16 - 1.399 1.359 -0.141
ENSG00000180304 E010 47.7054478 0.0005298833 7.055973e-02 2.689828e-01 15 64690461 64690549 89 - 1.720 1.647 -0.248
ENSG00000180304 E011 1.1413324 0.0946070426 1.283987e-03 1.814742e-02 15 64690723 64690907 185 - 0.000 0.531 13.762
ENSG00000180304 E012 0.3801504 0.0254502457 7.716713e-02   15 64690908 64691009 102 - 0.000 0.255 12.678
ENSG00000180304 E013 1.8857110 0.0162014897 1.316215e-03 1.851558e-02 15 64691010 64691433 424 - 0.161 0.649 2.943
ENSG00000180304 E014 64.1430234 0.0002715917 5.069300e-04 8.836704e-03 15 64691434 64691591 158 - 1.867 1.745 -0.413
ENSG00000180304 E015 8.1025149 0.0018648794 1.699888e-01 4.420747e-01 15 64691592 64693074 1483 - 0.889 1.025 0.506
ENSG00000180304 E016 0.7332058 0.0143353300 8.478721e-01 9.461266e-01 15 64693075 64693181 107 - 0.224 0.255 0.243
ENSG00000180304 E017 10.7199240 0.0012951689 1.000352e-07 5.839070e-06 15 64693182 64695963 2782 - 0.775 1.256 1.784
ENSG00000180304 E018 0.3727544 0.0166024421 4.897466e-01   15 64695964 64696050 87 - 0.088 0.185 1.243
ENSG00000180304 E019 0.9822863 0.2053778122 8.384166e-01 9.421068e-01 15 64696051 64696303 253 - 0.279 0.315 0.241
ENSG00000180304 E020 0.6336374 0.0272112554 1.360380e-02 9.817560e-02 15 64700485 64700590 106 - 0.000 0.368 13.364
ENSG00000180304 E021 41.1926175 0.0004588340 3.395110e-01 6.311939e-01 15 64703029 64703281 253 - 1.643 1.604 -0.135

Help

Please Click HERE to learn more details about the results from DEXseq.