ENSG00000180376

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000326595 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding protein_coding 6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 0.4068026 1.2204079 0.0000000 0.7079435 0.0000000 -6.9429928 0.05807500 0.174225 0.000000 -0.174225 0.493202611 0.002784103 FALSE TRUE
ENST00000341455 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding nonsense_mediated_decay 6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 0.5512360 1.0952274 0.0000000 0.6826955 0.0000000 -6.7881994 0.08729167 0.202175 0.000000 -0.202175 0.574705792 0.002784103 FALSE TRUE
ENST00000394672 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding protein_coding 6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 0.9112205 0.0000000 2.0996890 0.0000000 0.1875868 7.7208865 0.18745833 0.000000 0.383050 0.383050 0.002784103 0.002784103 FALSE TRUE
ENST00000439445 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding nonsense_mediated_decay 6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 0.1490875 0.0000000 0.4472626 0.0000000 0.4472626 5.5149512 0.02749167 0.000000 0.082475 0.082475 0.849349253 0.002784103   FALSE
ENST00000442522 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding protein_coding_CDS_not_defined 6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 0.3439260 0.3160431 0.3704813 0.1350477 0.1664017 0.2227631 0.06052500 0.050525 0.064875 0.014350 0.943905561 0.002784103 FALSE TRUE
ENST00000468108 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding retained_intron 6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 0.6929841 1.4145409 0.4689903 0.6856535 0.4689903 -1.5724288 0.09167500 0.184375 0.051800 -0.132575 0.532239364 0.002784103 FALSE TRUE
ENST00000472582 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding protein_coding_CDS_not_defined 6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 0.4022615 0.0000000 0.9374044 0.0000000 0.6142753 6.5659085 0.04226667 0.000000 0.082875 0.082875 0.366634237 0.002784103 TRUE TRUE
ENST00000476142 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding retained_intron 6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 0.2541379 0.6902553 0.0000000 0.2507607 0.0000000 -6.1298090 0.05090000 0.123275 0.000000 -0.123275 0.196070271 0.002784103 TRUE FALSE
ENST00000484441 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding retained_intron 6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 0.2722175 0.8166525 0.0000000 0.8166525 0.0000000 -6.3692091 0.02929167 0.087875 0.000000 -0.087875 0.842418997 0.002784103   FALSE
ENST00000487739 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding retained_intron 6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 0.3068927 0.2245730 0.0000000 0.2245730 0.0000000 -4.5519652 0.05254167 0.024175 0.000000 -0.024175 0.835370592 0.002784103   FALSE
MSTRG.20277.21 ENSG00000180376 No_inf pgKDN_inf CCDC66 protein_coding   6.730379 7.02979 7.623713 1.084574 2.080196 0.1168526 1.2809852 0.0000000 2.6496868 0.0000000 1.7279943 8.0551126 0.12073333 0.000000 0.234625 0.234625 0.361886238 0.002784103 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000180376 E001 0.0000000       3 56557161 56557162 2 +      
ENSG00000180376 E002 0.0000000       3 56557163 56557174 12 +      
ENSG00000180376 E003 0.0000000       3 56557175 56557187 13 +      
ENSG00000180376 E004 0.0000000       3 56557188 56557190 3 +      
ENSG00000180376 E005 0.0000000       3 56557191 56557202 12 +      
ENSG00000180376 E006 0.0000000       3 56557203 56557209 7 +      
ENSG00000180376 E007 0.0000000       3 56557210 56557210 1 +      
ENSG00000180376 E008 0.1186381 0.011938658 0.438321172   3 56557211 56557218 8 + 0.103 0.000 -10.785
ENSG00000180376 E009 0.1186381 0.011938658 0.438321172   3 56557219 56557227 9 + 0.103 0.000 -13.565
ENSG00000180376 E010 0.4906674 0.016358514 0.837623751   3 56557228 56557234 7 + 0.187 0.160 -0.270
ENSG00000180376 E011 0.8350986 0.012863739 0.025900226 0.14879663 3 56557235 56557253 19 + 0.417 0.087 -2.855
ENSG00000180376 E012 0.0000000       3 56557707 56557957 251 +      
ENSG00000180376 E013 0.0000000       3 56558845 56558845 1 +      
ENSG00000180376 E014 1.2065013 0.010190052 0.110323992 0.34845480 3 56558846 56558854 9 + 0.460 0.222 -1.493
ENSG00000180376 E015 1.2065013 0.010190052 0.110323992 0.34845480 3 56558855 56558910 56 + 0.460 0.222 -1.493
ENSG00000180376 E016 0.3714026 0.017042816 0.717698601   3 56559569 56559594 26 + 0.103 0.160 0.730
ENSG00000180376 E017 0.2448930 0.016545248 0.873213356   3 56560862 56561012 151 + 0.103 0.087 -0.270
ENSG00000180376 E018 0.1268540 0.012502361 0.655791117   3 56561013 56561222 210 + 0.000 0.087 12.203
ENSG00000180376 E019 0.0000000       3 56561257 56561378 122 +      
ENSG00000180376 E020 0.3813786 0.027799218 0.149719000   3 56563516 56563651 136 + 0.000 0.222 13.491
ENSG00000180376 E021 0.2541163 0.016685150 0.319055904   3 56563652 56563683 32 + 0.000 0.160 13.032
ENSG00000180376 E022 1.8116534 0.010181180 0.026624524 0.15126589 3 56563684 56563825 142 + 0.597 0.277 -1.730
ENSG00000180376 E023 1.5626107 0.008718535 0.018941187 0.12251798 3 56563826 56563905 80 + 0.567 0.222 -2.007
ENSG00000180376 E024 2.9054378 0.005161290 0.031318663 0.16704319 3 56563906 56564125 220 + 0.724 0.445 -1.270
ENSG00000180376 E025 0.1176306 0.011937678 0.438151250   3 56564126 56564156 31 + 0.103 0.000 -13.565
ENSG00000180376 E026 0.2373413 0.015919693 0.180064419   3 56565134 56565204 71 + 0.187 0.000 -14.335
ENSG00000180376 E027 0.0000000       3 56565205 56565205 1 +      
ENSG00000180376 E028 1.4438738 0.010383665 0.035394322 0.18005634 3 56566594 56566660 67 + 0.534 0.222 -1.855
ENSG00000180376 E029 1.8132615 0.007963976 0.090645245 0.31270484 3 56566661 56566740 80 + 0.567 0.325 -1.270
ENSG00000180376 E030 1.0797123 0.011086538 0.044798160 0.20698569 3 56566741 56566759 19 + 0.460 0.160 -2.078
ENSG00000180376 E031 0.0000000       3 56566783 56566949 167 +      
ENSG00000180376 E032 0.8356371 0.014935248 0.026150083 0.14959467 3 56566950 56566950 1 + 0.417 0.087 -2.855
ENSG00000180376 E033 2.3056993 0.007383234 0.110083138 0.34818344 3 56566951 56567053 103 + 0.626 0.408 -1.048
ENSG00000180376 E034 2.9410590 0.005237716 0.616006754 0.83343664 3 56569313 56570746 1434 + 0.626 0.565 -0.270
ENSG00000180376 E035 2.2035202 0.007276391 0.665179164 0.86076377 3 56571181 56571302 122 + 0.534 0.478 -0.270
ENSG00000180376 E036 0.1268540 0.012502361 0.655791117   3 56571303 56571379 77 + 0.000 0.087 12.203
ENSG00000180376 E037 0.3727544 0.017188095 0.716294015   3 56572337 56572428 92 + 0.103 0.160 0.730
ENSG00000180376 E038 0.2448930 0.016545248 0.873213356   3 56572429 56572910 482 + 0.103 0.087 -0.270
ENSG00000180376 E039 2.6028612 0.005696631 0.279777466 0.57302692 3 56592970 56593101 132 + 0.460 0.615 0.730
ENSG00000180376 E040 2.0947572 0.007928327 0.759594513 0.90562969 3 56593491 56593580 90 + 0.460 0.509 0.244
ENSG00000180376 E041 0.9872602 0.013343645 0.674557148 0.86523890 3 56593581 56593619 39 + 0.257 0.325 0.467
ENSG00000180376 E042 2.3150985 0.008169943 0.255959284 0.54800243 3 56593620 56593711 92 + 0.597 0.445 -0.730
ENSG00000180376 E043 1.8433747 0.009172600 0.890065434 0.96327959 3 56593712 56593741 30 + 0.460 0.445 -0.078
ENSG00000180376 E044 1.9809302 0.008634933 0.548801447 0.79366196 3 56593944 56594028 85 + 0.417 0.509 0.467
ENSG00000180376 E045 0.1187032 0.011949139 0.438301257   3 56598190 56598252 63 + 0.103 0.000 -13.565
ENSG00000180376 E046 0.3807797 0.018797063 0.148921007   3 56598260 56598300 41 + 0.000 0.222 13.495
ENSG00000180376 E047 1.3779508 0.009948551 0.062541424 0.25119967 3 56613589 56613610 22 + 0.187 0.478 1.900
ENSG00000180376 E048 3.6200529 0.006405041 0.020284734 0.12805677 3 56613611 56613750 140 + 0.460 0.771 1.382
ENSG00000180376 E049 0.4998298 0.017032186 0.428161949   3 56613751 56613754 4 + 0.103 0.222 1.315
ENSG00000180376 E050 2.2228784 0.007604005 0.607654609 0.82915330 3 56615128 56615217 90 + 0.460 0.538 0.382
ENSG00000180376 E051 2.6038764 0.005971847 0.280763677 0.57393171 3 56615218 56615272 55 + 0.460 0.615 0.730
ENSG00000180376 E052 0.8623909 0.014990465 0.915809219 0.97361142 3 56615273 56615417 145 + 0.257 0.277 0.145
ENSG00000180376 E053 0.1272623 0.012488272 0.655845076   3 56615869 56615903 35 + 0.000 0.087 12.203
ENSG00000180376 E054 0.1176306 0.011937678 0.438151250   3 56615904 56615921 18 + 0.103 0.000 -13.565
ENSG00000180376 E055 3.4486654 0.004073590 0.825614866 0.93687916 3 56615922 56616053 132 + 0.626 0.660 0.145
ENSG00000180376 E056 0.6189372 0.122708169 0.833272268 0.93988846 3 56616054 56617100 1047 + 0.187 0.222 0.315
ENSG00000180376 E057 0.0000000       3 56617101 56617111 11 +      
ENSG00000180376 E058 11.6529854 0.041009725 0.054142897 0.23159196 3 56617112 56617605 494 + 0.970 1.177 0.752
ENSG00000180376 E059 2.8847990 0.005291709 0.005064769 0.05010367 3 56617606 56618171 566 + 0.317 0.719 1.978
ENSG00000180376 E060 1.8544923 0.008863966 0.702974445 0.87919127 3 56618172 56618212 41 + 0.417 0.478 0.315
ENSG00000180376 E061 2.2476132 0.058832326 0.069936148 0.26755116 3 56618213 56619236 1024 + 0.317 0.615 1.538
ENSG00000180376 E062 0.2346346 0.016313282 0.179781413   3 56619237 56619270 34 + 0.187 0.000 -14.335
ENSG00000180376 E063 7.4959441 0.003684209 0.917968588 0.97422284 3 56619271 56619527 257 + 0.917 0.933 0.062
ENSG00000180376 E064 2.3359153 0.202951924 0.798974674 0.92450066 3 56619777 56619901 125 + 0.498 0.538 0.192
ENSG00000180376 E065 0.0000000       3 56621532 56621837 306 +      

Help

Please Click HERE to learn more details about the results from DEXseq.