ENSG00000180539

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000457302 ENSG00000180539 No_inf pgKDN_inf LINC02908 lncRNA lncRNA 8.344629 19.92637 2.323957 1.188521 0.309034 -3.094553 2.5095218 6.620931 0.0000000 2.2763295 0.00000000 -9.373068 0.18675000 0.315575 0.00000 -0.315575 1.897634e-01 1.715774e-05 FALSE FALSE
ENST00000623196 ENSG00000180539 No_inf pgKDN_inf LINC02908 lncRNA lncRNA 8.344629 19.92637 2.323957 1.188521 0.309034 -3.094553 2.0209433 2.688066 1.9776207 0.2872787 0.08393333 -0.440883 0.53862500 0.134525 0.89265 0.758125 2.149900e-04 1.715774e-05 FALSE TRUE
ENST00000671989 ENSG00000180539 No_inf pgKDN_inf LINC02908 lncRNA lncRNA 8.344629 19.92637 2.323957 1.188521 0.309034 -3.094553 0.5587032 1.055294 0.3463365 1.0552940 0.34633652 -1.579939 0.07710833 0.062125 0.10735 0.045225 8.003138e-01 1.715774e-05 FALSE FALSE
MSTRG.29540.2 ENSG00000180539 No_inf pgKDN_inf LINC02908 lncRNA   8.344629 19.92637 2.323957 1.188521 0.309034 -3.094553 3.2554610 9.562083 0.0000000 0.4838612 0.00000000 -9.902689 0.19750833 0.487775 0.00000 -0.487775 1.715774e-05 1.715774e-05 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000180539 E001 0.000000       9 137027464 137027910 447 +      
ENSG00000180539 E002 0.000000       9 137027911 137027911 1 +      
ENSG00000180539 E003 1.114114 0.0122012949 9.778277e-02 3.259489e-01 9 137031998 137032128 131 + 0.475 0.188 -1.873
ENSG00000180539 E004 10.761281 0.0015356653 1.026253e-09 8.730275e-08 9 137032129 137033115 987 + 1.346 0.776 -2.092
ENSG00000180539 E005 2.023295 0.0506794812 4.727347e-01 7.399591e-01 9 137033116 137033192 77 + 0.221 0.372 1.034
ENSG00000180539 E006 2.014041 0.0080096811 9.620295e-01 9.917057e-01 9 137033193 137033231 39 + 0.366 0.355 -0.066
ENSG00000180539 E007 5.279212 0.0028618995 6.712998e-01 8.636257e-01 9 137034650 137034779 130 + 0.697 0.629 -0.288
ENSG00000180539 E008 20.267082 0.0013953339 8.942479e-01 9.650039e-01 9 137034780 137035282 503 + 1.133 1.141 0.029
ENSG00000180539 E009 68.903328 0.0002438623 2.277247e-01 5.161633e-01 9 137035283 137037039 1757 + 1.603 1.654 0.175
ENSG00000180539 E010 17.839518 0.0010557714 4.637201e-01 7.335253e-01 9 137037040 137037284 245 + 1.154 1.080 -0.264
ENSG00000180539 E011 8.945977 0.0018404414 5.405324e-01 7.885816e-01 9 137037285 137037394 110 + 0.751 0.832 0.320
ENSG00000180539 E012 17.571972 0.0007960513 8.708825e-03 7.329226e-02 9 137037395 137037613 219 + 0.799 1.109 1.161
ENSG00000180539 E013 17.182724 0.0008747347 2.724728e-02 1.534783e-01 9 137037614 137037732 119 + 0.843 1.096 0.946
ENSG00000180539 E014 15.985907 0.0009147288 9.102379e-01 9.715752e-01 9 137037733 137037957 225 + 1.039 1.046 0.028

Help

Please Click HERE to learn more details about the results from DEXseq.