ENSG00000181019

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000320623 ENSG00000181019 No_inf pgKDN_inf NQO1 protein_coding protein_coding 51.49165 35.53166 53.54704 0.8963796 2.088098 0.591565 17.297926 15.178709 20.430584 1.3381114 1.314633 0.4284372 0.35157500 0.425500 0.380425 -0.045075 0.83578623 0.03953693 FALSE TRUE
ENST00000379046 ENSG00000181019 No_inf pgKDN_inf NQO1 protein_coding protein_coding 51.49165 35.53166 53.54704 0.8963796 2.088098 0.591565 6.664762 2.010316 10.185649 0.7065995 1.024899 2.3353006 0.12338333 0.057300 0.190700 0.133400 0.03953693 0.03953693 FALSE TRUE
ENST00000439109 ENSG00000181019 No_inf pgKDN_inf NQO1 protein_coding protein_coding 51.49165 35.53166 53.54704 0.8963796 2.088098 0.591565 3.557221 1.588785 0.000000 1.5887855 0.000000 -7.3208326 0.06037500 0.046300 0.000000 -0.046300 0.83389354 0.03953693 FALSE TRUE
ENST00000564043 ENSG00000181019 No_inf pgKDN_inf NQO1 protein_coding protein_coding 51.49165 35.53166 53.54704 0.8963796 2.088098 0.591565 18.082574 11.934654 19.116497 1.3808491 2.726034 0.6792076 0.34794167 0.334875 0.352650 0.017775 0.96763465 0.03953693 FALSE TRUE
MSTRG.11392.1 ENSG00000181019 No_inf pgKDN_inf NQO1 protein_coding   51.49165 35.53166 53.54704 0.8963796 2.088098 0.591565 4.158567 4.138542 2.848948 0.9411593 2.086104 -0.5371201 0.08618333 0.116150 0.057550 -0.058600 0.47935568 0.03953693 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000181019 E001 0.0000000       16 69705130 69705184 55 -      
ENSG00000181019 E002 0.0000000       16 69706996 69707207 212 -      
ENSG00000181019 E003 33.4095518 0.0004874863 0.04399242 0.20500147 16 69709401 69710114 714 - 1.487 1.586 0.340
ENSG00000181019 E004 14.9174234 0.0010264476 0.28257990 0.57621457 16 69710115 69710726 612 - 1.163 1.241 0.277
ENSG00000181019 E005 12.9146039 0.0040496121 0.01193176 0.09017285 16 69710727 69710781 55 - 1.037 1.241 0.730
ENSG00000181019 E006 33.9176802 0.0123153085 0.25529310 0.54724553 16 69710782 69710961 180 - 1.575 1.496 -0.270
ENSG00000181019 E007 39.1832842 0.0003747012 0.01609679 0.11010325 16 69710962 69711070 109 - 1.650 1.537 -0.387
ENSG00000181019 E008 16.7380440 0.0009271940 0.16157736 0.42974849 16 69711071 69711074 4 - 1.290 1.190 -0.354
ENSG00000181019 E009 62.2548341 0.0002386833 0.29462921 0.58795752 16 69711075 69711281 207 - 1.783 1.819 0.122
ENSG00000181019 E010 38.6036331 0.0037664185 0.81868000 0.93393975 16 69713028 69713129 102 - 1.602 1.589 -0.041
ENSG00000181019 E011 52.0858116 0.0003215755 0.53100006 0.78175895 16 69714964 69715077 114 - 1.712 1.736 0.080
ENSG00000181019 E012 0.0000000       16 69717993 69718122 130 -      
ENSG00000181019 E013 61.3869995 0.0003143067 0.60878992 0.82970535 16 69718123 69718253 131 - 1.802 1.782 -0.067
ENSG00000181019 E014 45.6681273 0.0016284645 0.59336247 0.82076406 16 69718370 69718534 165 - 1.679 1.653 -0.086
ENSG00000181019 E015 15.9680777 0.0010126248 0.99930481 1.00000000 16 69726433 69726500 68 - 1.229 1.227 -0.005
ENSG00000181019 E016 9.5142998 0.0436466983 0.99812147 1.00000000 16 69726501 69726668 168 - 1.020 1.020 -0.001
ENSG00000181019 E017 0.2536433 0.0159988393 0.16528605   16 69740411 69740472 62 - 0.000 0.192 10.184

Help

Please Click HERE to learn more details about the results from DEXseq.