ENSG00000181027

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000318584 ENSG00000181027 No_inf pgKDN_inf FKRP protein_coding protein_coding 11.49862 13.01068 9.771177 2.034576 0.2559443 -0.4127253 2.7282071 0.8793568 2.04180527 0.8793568 1.19799095 1.2060596 0.28325833 0.085300 0.213500 0.128200 0.77941709 0.02036144 FALSE TRUE
ENST00000593877 ENSG00000181027 No_inf pgKDN_inf FKRP protein_coding protein_coding 11.49862 13.01068 9.771177 2.034576 0.2559443 -0.4127253 1.0613971 1.6936054 0.61759078 0.6564627 0.36313946 -1.4406951 0.08549167 0.121500 0.066125 -0.055375 0.83030288 0.02036144   FALSE
ENST00000593902 ENSG00000181027 No_inf pgKDN_inf FKRP protein_coding protein_coding 11.49862 13.01068 9.771177 2.034576 0.2559443 -0.4127253 1.3747894 1.7373655 2.38700270 1.0168173 1.31794244 0.4560501 0.12376667 0.123925 0.247375 0.123450 0.83231762 0.02036144 FALSE TRUE
ENST00000594467 ENSG00000181027 No_inf pgKDN_inf FKRP protein_coding protein_coding 11.49862 13.01068 9.771177 2.034576 0.2559443 -0.4127253 0.2476155 0.7428465 0.00000000 0.7428465 0.00000000 -6.2342839 0.02026667 0.060800 0.000000 -0.060800 0.88195033 0.02036144 FALSE TRUE
ENST00000595570 ENSG00000181027 No_inf pgKDN_inf FKRP protein_coding protein_coding 11.49862 13.01068 9.771177 2.034576 0.2559443 -0.4127253 0.3402623 0.5996683 0.00000000 0.3695673 0.00000000 -5.9299526 0.03137500 0.051975 0.000000 -0.051975 0.59928745 0.02036144 FALSE TRUE
ENST00000597339 ENSG00000181027 No_inf pgKDN_inf FKRP protein_coding protein_coding_CDS_not_defined 11.49862 13.01068 9.771177 2.034576 0.2559443 -0.4127253 0.9920625 2.7124817 0.00000000 1.8259196 0.00000000 -8.0887786 0.06097500 0.168400 0.000000 -0.168400 0.09190022 0.02036144   FALSE
ENST00000598271 ENSG00000181027 No_inf pgKDN_inf FKRP protein_coding protein_coding 11.49862 13.01068 9.771177 2.034576 0.2559443 -0.4127253 0.3015730 0.8138580 0.09086097 0.8138580 0.09086097 -3.0300276 0.02934167 0.078950 0.009075 -0.069875 1.00000000 0.02036144 FALSE TRUE
ENST00000600629 ENSG00000181027 No_inf pgKDN_inf FKRP protein_coding protein_coding 11.49862 13.01068 9.771177 2.034576 0.2559443 -0.4127253 0.6966043 0.5573703 0.42739287 0.5573703 0.42739287 -0.3753610 0.05165833 0.052900 0.041200 -0.011700 0.99411105 0.02036144 FALSE TRUE
ENST00000600646 ENSG00000181027 No_inf pgKDN_inf FKRP protein_coding protein_coding_CDS_not_defined 11.49862 13.01068 9.771177 2.034576 0.2559443 -0.4127253 1.0714034 0.9835069 1.16447005 0.4529675 0.67872350 0.2414081 0.09776667 0.089750 0.114550 0.024800 1.00000000 0.02036144   FALSE
ENST00000601299 ENSG00000181027 No_inf pgKDN_inf FKRP protein_coding protein_coding 11.49862 13.01068 9.771177 2.034576 0.2559443 -0.4127253 1.0943793 0.0000000 2.45802694 0.0000000 0.91993649 7.9472143 0.09729167 0.000000 0.246400 0.246400 0.02036144 0.02036144 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000181027 E001 0.0000000       19 46746046 46746053 8 +      
ENSG00000181027 E002 0.0000000       19 46746054 46746056 3 +      
ENSG00000181027 E003 0.0000000       19 46746057 46746057 1 +      
ENSG00000181027 E004 0.0000000       19 46746058 46746058 1 +      
ENSG00000181027 E005 0.0000000       19 46746059 46746060 2 +      
ENSG00000181027 E006 1.0057339 0.0119558254 3.436153e-02 0.177040017 19 46746061 46746086 26 + 0.097 0.428 2.744
ENSG00000181027 E007 1.2512260 0.0110948576 6.830525e-02 0.263762812 19 46746087 46746090 4 + 0.176 0.465 1.937
ENSG00000181027 E008 0.0000000       19 46746910 46746992 83 +      
ENSG00000181027 E009 0.7609946 0.0146040577 1.221487e-02 0.091538256 19 46747234 46747294 61 + 0.000 0.387 13.639
ENSG00000181027 E010 0.6338583 0.0157219695 2.547984e-02 0.147118024 19 46747295 46747305 11 + 0.000 0.342 13.424
ENSG00000181027 E011 0.2530140 0.3214355881 3.446070e-01   19 46747579 46747658 80 + 0.000 0.170 12.003
ENSG00000181027 E012 0.1265070 0.0125348246 5.837258e-01   19 46747659 46747681 23 + 0.000 0.093 11.392
ENSG00000181027 E013 0.2530140 0.3214355881 3.446070e-01   19 46747682 46747732 51 + 0.000 0.170 12.003
ENSG00000181027 E014 1.6230056 0.0741918143 9.646698e-02 0.323516978 19 46747733 46748026 294 + 0.243 0.531 1.673
ENSG00000181027 E015 3.4527674 0.0692296971 4.275219e-01 0.706086632 19 46748027 46748088 62 + 0.574 0.705 0.565
ENSG00000181027 E016 4.4271160 0.0034590961 6.720624e-01 0.864109105 19 46748515 46748621 107 + 0.699 0.763 0.259
ENSG00000181027 E017 2.4428731 0.0131831583 5.362834e-01 0.785655532 19 46748622 46748665 44 + 0.574 0.499 -0.353
ENSG00000181027 E018 0.8796967 0.1029413787 8.689417e-02 0.305535679 19 46748666 46748717 52 + 0.097 0.387 2.522
ENSG00000181027 E019 0.3715287 0.1710979053 6.741692e-01   19 46748718 46748757 40 + 0.097 0.170 0.937
ENSG00000181027 E020 0.3715287 0.1710979053 6.741692e-01   19 46748758 46748774 17 + 0.097 0.170 0.937
ENSG00000181027 E021 1.6331057 0.0081404344 1.376520e-02 0.098895971 19 46748775 46748884 110 + 0.176 0.560 2.396
ENSG00000181027 E022 0.4913966 0.0772821726 9.436260e-01   19 46748885 46748963 79 + 0.176 0.170 -0.064
ENSG00000181027 E023 0.6157586 0.0350286800 7.279092e-01 0.891400342 19 46753836 46754101 266 + 0.176 0.235 0.522
ENSG00000181027 E024 0.2530140 0.3214355881 3.446070e-01   19 46754102 46754181 80 + 0.000 0.170 12.003
ENSG00000181027 E025 0.0000000       19 46754249 46754315 67 +      
ENSG00000181027 E026 6.6230797 0.0028587972 9.777908e-01 0.996714619 19 46755412 46755534 123 + 0.875 0.887 0.044
ENSG00000181027 E027 104.1491712 0.0002204119 3.861134e-05 0.001067443 19 46755535 46758575 3041 + 2.042 2.002 -0.135
ENSG00000181027 E028 0.0000000       19 46761833 46762006 174 +      
ENSG00000181027 E029 1.3499735 0.1065942225 8.545536e-01 0.948727840 19 46776652 46776988 337 + 0.352 0.387 0.200

Help

Please Click HERE to learn more details about the results from DEXseq.