ENSG00000181220

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340622 ENSG00000181220 No_inf pgKDN_inf ZNF746 protein_coding protein_coding 11.68746 11.20191 11.83427 0.5479741 0.3149449 0.07915752 4.439204 2.909228 3.5399873 1.7365717 1.1819841 0.2822271 0.3853417 0.282050 0.304550 0.022500 0.8467833104 0.0005131272 FALSE TRUE
ENST00000458143 ENSG00000181220 No_inf pgKDN_inf ZNF746 protein_coding protein_coding 11.68746 11.20191 11.83427 0.5479741 0.3149449 0.07915752 4.680961 5.029035 7.3231262 1.5433090 0.8335763 0.5412809 0.4001833 0.433600 0.615425 0.181825 0.6730912785 0.0005131272 FALSE TRUE
ENST00000471735 ENSG00000181220 No_inf pgKDN_inf ZNF746 protein_coding retained_intron 11.68746 11.20191 11.83427 0.5479741 0.3149449 0.07915752 1.068248 1.860993 0.0000000 0.4561928 0.0000000 -7.5476605 0.0879500 0.162225 0.000000 -0.162225 0.0005131272 0.0005131272 FALSE FALSE
ENST00000644635 ENSG00000181220 No_inf pgKDN_inf ZNF746 protein_coding protein_coding 11.68746 11.20191 11.83427 0.5479741 0.3149449 0.07915752 1.217770 1.148462 0.6369045 0.4451670 0.6369045 -0.8405862 0.1021250 0.099250 0.051375 -0.047875 0.5821974349 0.0005131272 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000181220 E001 0.0000000       7 149472696 149472792 97 -      
ENSG00000181220 E002 0.1271363 0.0123787179 0.4879017526   7 149472793 149472793 1 - 0.000 0.100 8.732
ENSG00000181220 E003 104.7849474 0.0002136185 0.0002721717 0.005369169 7 149472794 149474103 1310 - 1.982 2.064 0.275
ENSG00000181220 E004 66.3336987 0.0002814670 0.0008313060 0.012992797 7 149474104 149475377 1274 - 1.876 1.772 -0.351
ENSG00000181220 E005 7.4519389 0.0021832948 0.9955503662 1.000000000 7 149475378 149475480 103 - 0.927 0.928 0.005
ENSG00000181220 E006 2.2867766 0.0067702656 0.0602583793 0.246362563 7 149475481 149475483 3 - 0.629 0.359 -1.339
ENSG00000181220 E007 7.9641642 0.0021067502 0.6041690066 0.827371323 7 149476922 149477047 126 - 0.927 0.978 0.191
ENSG00000181220 E008 9.5349441 0.0062583722 0.9840538720 0.998727939 7 149477564 149477755 192 - 1.023 1.022 -0.001
ENSG00000181220 E009 1.3964896 0.0093800439 0.0001303326 0.002944851 7 149477756 149477900 145 - 0.000 0.584 13.734
ENSG00000181220 E010 6.7094986 0.0029940277 0.7539668146 0.903187877 7 149487620 149491953 4334 - 0.902 0.871 -0.116
ENSG00000181220 E011 6.6473993 0.1274237243 0.1229522183 0.371114140 7 149492859 149492972 114 - 0.993 0.731 -1.015
ENSG00000181220 E012 5.0944091 0.0036400404 0.1228512395 0.371009505 7 149493989 149494070 82 - 0.862 0.687 -0.701
ENSG00000181220 E013 2.4695609 0.0710233013 0.3547648637 0.644455647 7 149494071 149494115 45 - 0.457 0.612 0.732
ENSG00000181220 E014 6.6383719 0.0043759189 0.3750523115 0.662683246 7 149494204 149494503 300 - 0.834 0.928 0.361
ENSG00000181220 E015 3.6552301 0.0041342833 0.6425119190 0.848366779 7 149497513 149497817 305 - 0.695 0.638 -0.240

Help

Please Click HERE to learn more details about the results from DEXseq.