ENSG00000181555

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000409792 ENSG00000181555 No_inf pgKDN_inf SETD2 protein_coding protein_coding 19.77056 26.05679 17.31576 0.8295958 0.485543 -0.5892939 1.9339529 2.532900 2.2665055 1.033578 0.8430162 -0.1596541 0.09885833 0.100525 0.132100 0.031575 0.93205228 0.01190147 FALSE TRUE
ENST00000685005 ENSG00000181555 No_inf pgKDN_inf SETD2 protein_coding protein_coding 19.77056 26.05679 17.31576 0.8295958 0.485543 -0.5892939 0.4639478 0.000000 0.8630995 0.000000 0.8630995 6.4480742 0.02907500 0.000000 0.053250 0.053250 0.82434680 0.01190147 FALSE TRUE
ENST00000686773 ENSG00000181555 No_inf pgKDN_inf SETD2 protein_coding nonsense_mediated_decay 19.77056 26.05679 17.31576 0.8295958 0.485543 -0.5892939 1.3890584 0.000000 2.6792250 0.000000 0.9047039 8.0710466 0.08151667 0.000000 0.151675 0.151675 0.01190147 0.01190147 TRUE TRUE
ENST00000687657 ENSG00000181555 No_inf pgKDN_inf SETD2 protein_coding retained_intron 19.77056 26.05679 17.31576 0.8295958 0.485543 -0.5892939 2.7037047 4.891401 2.1815092 1.112370 0.8390962 -1.1612695 0.12612500 0.187750 0.126525 -0.061225 0.83117113 0.01190147 FALSE TRUE
ENST00000691544 ENSG00000181555 No_inf pgKDN_inf SETD2 protein_coding protein_coding 19.77056 26.05679 17.31576 0.8295958 0.485543 -0.5892939 2.7303100 1.480710 4.0147230 1.480710 1.3589388 1.4328899 0.15682500 0.060025 0.236775 0.176750 0.25496383 0.01190147 FALSE TRUE
MSTRG.20081.22 ENSG00000181555 No_inf pgKDN_inf SETD2 protein_coding   19.77056 26.05679 17.31576 0.8295958 0.485543 -0.5892939 5.3538726 8.857275 2.1221699 1.073232 2.1221699 -2.0561684 0.25693333 0.340175 0.117225 -0.222950 0.06613522 0.01190147 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000181555 E001 0.0000000       3 47016428 47016428 1 -      
ENSG00000181555 E002 0.1268540 0.0123386612 7.232211e-01   3 47016429 47016435 7 - 0.000 0.083 9.547
ENSG00000181555 E003 0.4982566 0.0152649972 4.813773e-01   3 47016436 47016442 7 - 0.108 0.214 1.167
ENSG00000181555 E004 0.6158873 0.0143079167 9.036073e-01 9.690425e-01 3 47016443 47016444 2 - 0.195 0.214 0.167
ENSG00000181555 E005 3.8272110 0.0037090708 6.569197e-01 8.564251e-01 3 47016445 47016517 73 - 0.643 0.701 0.245
ENSG00000181555 E006 20.3761581 0.0008739402 2.406274e-01 5.298471e-01 3 47016518 47016688 171 - 1.275 1.354 0.277
ENSG00000181555 E007 83.6333443 0.0003839342 9.796308e-02 3.263793e-01 3 47016689 47017254 566 - 1.887 1.942 0.186
ENSG00000181555 E008 19.9885557 0.0007896611 5.106132e-01 7.680560e-01 3 47017638 47017739 102 - 1.288 1.333 0.159
ENSG00000181555 E009 18.7467458 0.0007552035 5.240264e-01 7.771561e-01 3 47019760 47019840 81 - 1.262 1.307 0.159
ENSG00000181555 E010 0.0000000       3 47028228 47028308 81 -      
ENSG00000181555 E011 0.1176306 0.0117218758 3.979702e-01   3 47037665 47037665 1 - 0.108 0.000 -13.248
ENSG00000181555 E012 16.5580862 0.0008033638 2.062643e-01 4.898789e-01 3 47037666 47037777 112 - 1.180 1.274 0.330
ENSG00000181555 E013 0.7519646 0.0351718254 1.875006e-01 4.656134e-01 3 47041360 47041483 124 - 0.108 0.314 1.904
ENSG00000181555 E014 22.6393873 0.0191929952 1.093181e-01 3.470213e-01 3 47042561 47042700 140 - 1.281 1.418 0.477
ENSG00000181555 E015 22.1983642 0.0113104137 6.409652e-01 8.476017e-01 3 47046487 47046621 135 - 1.336 1.374 0.133
ENSG00000181555 E016 0.2357071 0.0157109532 1.566761e-01   3 47046622 47047027 406 - 0.195 0.000 -14.170
ENSG00000181555 E017 75.2904600 0.0002675664 3.533738e-03 3.896721e-02 3 47056821 47057490 670 - 1.813 1.914 0.343
ENSG00000181555 E018 0.1268540 0.0123386612 7.232211e-01   3 47061401 47061494 94 - 0.000 0.083 11.864
ENSG00000181555 E019 0.0000000       3 47062160 47062162 3 -      
ENSG00000181555 E020 27.9788967 0.0005469559 5.997660e-01 8.245853e-01 3 47062163 47062346 184 - 1.436 1.468 0.109
ENSG00000181555 E021 0.3716209 0.0166502618 7.833408e-01   3 47064555 47064630 76 - 0.108 0.153 0.582
ENSG00000181555 E022 9.8542977 0.0015365788 7.969823e-01 9.233443e-01 3 47067070 47067118 49 - 1.014 1.039 0.092
ENSG00000181555 E023 1.3707121 0.0096371478 2.954570e-01 5.886983e-01 3 47067119 47067397 279 - 0.267 0.430 0.997
ENSG00000181555 E024 0.2447669 0.0163760498 8.187999e-01   3 47073005 47073147 143 - 0.108 0.083 -0.418
ENSG00000181555 E025 1.2601648 0.0422233946 2.941044e-02 1.611472e-01 3 47079512 47079611 100 - 0.108 0.463 2.751
ENSG00000181555 E026 0.6251079 0.0150960715 2.958318e-01 5.889439e-01 3 47079612 47079739 128 - 0.108 0.266 1.582
ENSG00000181555 E027 8.4525780 0.0017035449 2.502913e-02 1.455407e-01 3 47079740 47080800 1061 - 0.823 1.048 0.845
ENSG00000181555 E028 3.0908953 0.0053603244 5.017311e-01 7.615773e-01 3 47080801 47080898 98 - 0.550 0.642 0.412
ENSG00000181555 E029 2.2381398 0.0496471777 2.420061e-01 5.316859e-01 3 47080899 47080915 17 - 0.383 0.574 0.960
ENSG00000181555 E030 5.0665158 0.0267596230 4.883284e-01 7.516625e-01 3 47080916 47081083 168 - 0.720 0.813 0.375
ENSG00000181555 E031 66.8159064 0.0062619988 4.884335e-01 7.517386e-01 3 47083720 47084382 663 - 1.803 1.839 0.120
ENSG00000181555 E032 13.9988111 0.0010037775 4.123564e-01 6.936353e-01 3 47086195 47086299 105 - 1.204 1.143 -0.216
ENSG00000181555 E033 6.5258287 0.0031406129 9.155334e-01 9.735314e-01 3 47086300 47086314 15 - 0.876 0.866 -0.035
ENSG00000181555 E034 0.6353043 0.0149746143 4.481963e-02 2.070317e-01 3 47086315 47086698 384 - 0.000 0.314 14.017
ENSG00000181555 E035 9.1327561 0.0015267422 5.450552e-01 7.911363e-01 3 47088113 47088183 71 - 0.964 1.022 0.216
ENSG00000181555 E036 10.0936504 0.0017032501 1.874500e-03 2.433195e-02 3 47088184 47088247 64 - 0.841 1.137 1.096
ENSG00000181555 E037 12.6772532 0.0011086780 9.934855e-01 1.000000e+00 3 47097955 47098081 127 - 1.129 1.130 0.005
ENSG00000181555 E038 3.3978193 0.0054754399 3.729477e-04 6.919172e-03 3 47098082 47099940 1859 - 0.267 0.784 2.582
ENSG00000181555 E039 10.3562198 0.0014122265 1.119764e-02 8.664755e-02 3 47101458 47101555 98 - 1.164 0.946 -0.794
ENSG00000181555 E040 10.8799268 0.0013350688 8.975721e-02 3.112381e-01 3 47103346 47103423 78 - 1.147 1.005 -0.516
ENSG00000181555 E041 12.4643470 0.0024097748 4.106119e-02 1.966508e-01 3 47105997 47106120 124 - 1.212 1.048 -0.588
ENSG00000181555 E042 11.4839808 0.0012634558 4.165022e-02 1.984069e-01 3 47113876 47114004 129 - 1.180 1.014 -0.603
ENSG00000181555 E043 7.8506349 0.0019985131 5.030585e-01 7.626531e-01 3 47116623 47116754 132 - 0.977 0.914 -0.238
ENSG00000181555 E044 0.0000000       3 47116755 47117013 259 -      
ENSG00000181555 E045 0.0000000       3 47119452 47119780 329 -      
ENSG00000181555 E046 16.7478284 0.0081051976 5.360023e-02 2.305264e-01 3 47120182 47120482 301 - 1.324 1.175 -0.524
ENSG00000181555 E047 75.6540930 0.0005700127 4.387099e-10 4.010403e-08 3 47120483 47122969 2487 - 1.988 1.780 -0.698
ENSG00000181555 E048 32.6998089 0.0019125294 1.160244e-02 8.864252e-02 3 47122970 47124548 1579 - 1.593 1.462 -0.451
ENSG00000181555 E049 2.1982856 0.0078489814 2.794042e-01 5.727191e-01 3 47126648 47126663 16 - 0.583 0.430 -0.740
ENSG00000181555 E050 0.2435110 0.0163624148 8.191400e-01   3 47163428 47163576 149 - 0.108 0.083 -0.418
ENSG00000181555 E051 2.9347662 0.0083412163 2.671901e-01 5.604197e-01 3 47163854 47164113 260 - 0.670 0.522 -0.659

Help

Please Click HERE to learn more details about the results from DEXseq.