ENSG00000182150

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000456993 ENSG00000182150 No_inf pgKDN_inf ERCC6L2 protein_coding nonsense_mediated_decay 7.703837 7.211876 7.994021 1.211747 0.5786131 0.1483514 0.4094361 1.22830817 0.00000000 0.42057862 0.00000000 -6.9522266 0.05886667 0.176600 0.000000 -0.176600 0.0560619 0.047543 FALSE TRUE
ENST00000653738 ENSG00000182150 No_inf pgKDN_inf ERCC6L2 protein_coding protein_coding 7.703837 7.211876 7.994021 1.211747 0.5786131 0.1483514 0.8382662 0.00000000 1.77445620 0.00000000 0.59269104 7.4793407 0.10815000 0.000000 0.224400 0.224400 0.0475430 0.047543 FALSE TRUE
ENST00000659728 ENSG00000182150 No_inf pgKDN_inf ERCC6L2 protein_coding nonsense_mediated_decay 7.703837 7.211876 7.994021 1.211747 0.5786131 0.1483514 0.4896290 0.00000000 0.06277444 0.00000000 0.06277444 2.8634319 0.06693333 0.000000 0.009750 0.009750 0.8281822 0.047543 TRUE TRUE
ENST00000661047 ENSG00000182150 No_inf pgKDN_inf ERCC6L2 protein_coding nonsense_mediated_decay 7.703837 7.211876 7.994021 1.211747 0.5786131 0.1483514 0.1760361 0.05378029 0.47432808 0.05378029 0.24294013 2.9248021 0.02353333 0.008675 0.061925 0.053250 0.5233328 0.047543 FALSE TRUE
ENST00000668220 ENSG00000182150 No_inf pgKDN_inf ERCC6L2 protein_coding protein_coding 7.703837 7.211876 7.994021 1.211747 0.5786131 0.1483514 3.1569023 2.35613243 3.68341635 0.38863943 0.56609664 0.6424251 0.40494167 0.333000 0.452025 0.119025 0.7846195 0.047543 FALSE TRUE
ENST00000683937 ENSG00000182150 No_inf pgKDN_inf ERCC6L2 protein_coding protein_coding 7.703837 7.211876 7.994021 1.211747 0.5786131 0.1483514 0.6683894 0.87232503 0.34554993 0.57523379 0.34554993 -1.3112580 0.08974167 0.136450 0.044325 -0.092125 0.8240394 0.047543 FALSE TRUE
MSTRG.29053.24 ENSG00000182150 No_inf pgKDN_inf ERCC6L2 protein_coding   7.703837 7.211876 7.994021 1.211747 0.5786131 0.1483514 0.3906422 1.17192655 0.00000000 1.17192655 0.00000000 -6.8849966 0.03660000 0.109800 0.000000 -0.109800 0.8357862 0.047543 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000182150 E001 0.3728195 0.0166273192 0.554354628   9 95871264 95871269 6 + 0.092 0.179 1.109
ENSG00000182150 E002 0.0000000       9 95875059 95875132 74 +      
ENSG00000182150 E003 0.0000000       9 95875618 95875649 32 +      
ENSG00000182150 E004 0.0000000       9 95875650 95875655 6 +      
ENSG00000182150 E005 0.0000000       9 95875656 95875660 5 +      
ENSG00000182150 E006 0.0000000       9 95875661 95875676 16 +      
ENSG00000182150 E007 0.0000000       9 95875677 95875683 7 +      
ENSG00000182150 E008 0.0000000       9 95875684 95875690 7 +      
ENSG00000182150 E009 0.0000000       9 95875691 95875701 11 +      
ENSG00000182150 E010 0.0000000       9 95875702 95875712 11 +      
ENSG00000182150 E011 0.0000000       9 95875713 95875762 50 +      
ENSG00000182150 E012 0.0000000       9 95875763 95876005 243 +      
ENSG00000182150 E013 0.5077596 0.0151120100 0.040109533 0.19411949 9 95876006 95876084 79 + 0.000 0.305 13.771
ENSG00000182150 E014 0.8695332 0.2013773140 0.294181827 0.58754799 9 95876143 95877105 963 + 0.168 0.356 1.433
ENSG00000182150 E015 4.1403324 0.0377924938 0.651252604 0.85308533 9 95880869 95881293 425 + 0.738 0.682 -0.231
ENSG00000182150 E016 1.8487034 0.3181001337 0.613442471 0.83193816 9 95881294 95883331 2038 + 0.382 0.517 0.697
ENSG00000182150 E017 2.7995522 0.0112112324 0.610867025 0.83074465 9 95897849 95897971 123 + 0.609 0.549 -0.269
ENSG00000182150 E018 0.0000000       9 95906588 95906710 123 +      
ENSG00000182150 E019 0.7083097 0.0134768870 0.010993114 0.08558829 9 95907078 95907122 45 + 0.383 0.000 -14.743
ENSG00000182150 E020 2.2923171 0.0086274160 0.133287370 0.38779217 9 95907123 95907271 149 + 0.609 0.402 -1.006
ENSG00000182150 E021 4.1515019 0.0035770697 0.835811506 0.94107968 9 95915668 95915829 162 + 0.720 0.705 -0.061
ENSG00000182150 E022 3.9518370 0.0048003298 0.124723443 0.37437190 9 95916227 95916434 208 + 0.583 0.784 0.846
ENSG00000182150 E023 1.6134683 0.0721605718 0.186963212 0.46486099 9 95921175 95921182 8 + 0.288 0.517 1.279
ENSG00000182150 E024 3.4366984 0.1139117467 0.666233951 0.86126080 9 95921183 95921315 133 + 0.609 0.682 0.316
ENSG00000182150 E025 1.9695997 0.2632632908 0.566594569 0.80470374 9 95922305 95922418 114 + 0.423 0.517 0.473
ENSG00000182150 E026 0.1272623 0.0125079937 0.512342572   9 95922419 95922423 5 + 0.000 0.098 12.039
ENSG00000182150 E027 2.5689005 0.1292762329 0.998842196 1.00000000 9 95923260 95923379 120 + 0.555 0.549 -0.029
ENSG00000182150 E028 1.8245586 0.0080378373 0.497134233 0.75788736 9 95928079 95928150 72 + 0.494 0.402 -0.476
ENSG00000182150 E029 0.0000000       9 95928151 95928277 127 +      
ENSG00000182150 E030 3.2892596 0.0505009582 0.723971117 0.88908097 9 95928719 95928864 146 + 0.657 0.607 -0.212
ENSG00000182150 E031 0.1186381 0.0118523001 0.564823498   9 95928865 95929117 253 + 0.092 0.000 -12.631
ENSG00000182150 E032 1.4568060 0.0111511106 0.623497616 0.83785787 9 95941454 95941549 96 + 0.423 0.356 -0.376
ENSG00000182150 E033 0.7447540 0.0142084511 0.382117012 0.66832373 9 95941550 95942518 969 + 0.168 0.305 1.109
ENSG00000182150 E034 0.2451451 0.0162954193 0.971356971   9 95954728 95954922 195 + 0.092 0.098 0.109
ENSG00000182150 E035 2.0684734 0.0137842502 0.537944896 0.78684683 9 95955914 95956013 100 + 0.526 0.444 -0.405
ENSG00000182150 E036 4.2761631 0.1016682662 0.929077565 0.97903305 9 95966562 95966714 153 + 0.739 0.705 -0.139
ENSG00000182150 E037 0.3804973 0.0158445921 0.094135091   9 95966715 95967318 604 + 0.000 0.246 13.427
ENSG00000182150 E038 0.1271363 0.0124397995 0.512422796   9 95967319 95967458 140 + 0.000 0.098 12.040
ENSG00000182150 E039 0.3641952 0.0166116847 0.613345614   9 95967459 95967625 167 + 0.168 0.098 -0.891
ENSG00000182150 E040 0.3804973 0.0158445921 0.094135091   9 95967626 95968840 1215 + 0.000 0.246 13.427
ENSG00000182150 E041 0.5896716 0.0152389721 0.023333452 0.13953502 9 95970391 95970575 185 + 0.338 0.000 -14.548
ENSG00000182150 E042 3.2571054 0.0044975952 0.044036008 0.20508057 9 95970576 95970656 81 + 0.739 0.482 -1.139
ENSG00000182150 E043 0.3631878 0.0165758951 0.613736260   9 95970657 95971543 887 + 0.168 0.098 -0.891
ENSG00000182150 E044 0.2357071 0.0157837654 0.259171245   9 95971544 95971595 52 + 0.168 0.000 -13.496
ENSG00000182150 E045 0.7538810 0.0143782113 0.082554779 0.29594612 9 95971596 95971932 337 + 0.092 0.356 2.431
ENSG00000182150 E046 22.3676077 0.0007525629 0.717981425 0.88650726 9 95971933 95973088 1156 + 1.373 1.364 -0.033
ENSG00000182150 E047 2.6943710 0.0121314475 0.912380480 0.97213159 9 95978061 95978077 17 + 0.555 0.579 0.109
ENSG00000182150 E048 5.3538499 0.0034967144 0.295173406 0.58843210 9 95978078 95978215 138 + 0.853 0.746 -0.421
ENSG00000182150 E049 0.3714026 0.0169362424 0.553762372   9 95978216 95979714 1499 + 0.092 0.179 1.109
ENSG00000182150 E050 1.0978422 0.0357910179 0.805035705 0.92785117 9 95979715 95981064 1350 + 0.338 0.305 -0.213
ENSG00000182150 E051 0.8726492 0.0392229558 0.238171490 0.52708305 9 95982910 95984665 1756 + 0.168 0.356 1.431
ENSG00000182150 E052 3.0282570 0.0174092609 0.216611917 0.50276486 9 95994214 95997245 3032 + 0.679 0.517 -0.721
ENSG00000182150 E053 0.2458395 0.0163225205 0.970523469   9 95997246 95997413 168 + 0.092 0.098 0.109
ENSG00000182150 E054 7.5212347 0.0020527501 0.061817309 0.24981168 9 96004520 96004701 182 + 1.008 0.835 -0.653
ENSG00000182150 E055 0.7616853 0.0309198188 0.008706913 0.07329226 9 96004702 96005415 714 + 0.000 0.402 14.219
ENSG00000182150 E056 43.3880322 0.0005864423 0.607610853 0.82915330 9 96012225 96013647 1423 + 1.652 1.643 -0.029
ENSG00000182150 E057 62.5623190 0.0069592087 0.189549945 0.46828761 9 96013648 96018447 4800 + 1.769 1.835 0.222
ENSG00000182150 E058 0.1268540 0.0123019105 0.512708547   9 96038876 96039127 252 + 0.000 0.098 12.040
ENSG00000182150 E059 0.5070043 0.0156344878 0.040327645 0.19472079 9 96039128 96040580 1453 + 0.000 0.305 13.771
ENSG00000182150 E060 0.0000000       9 96120367 96121154 788 +      

Help

Please Click HERE to learn more details about the results from DEXseq.