ENSG00000182307

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000331434 ENSG00000182307 No_inf pgKDN_inf C8orf33 protein_coding protein_coding 26.73889 21.43358 29.71028 0.363717 0.3160231 0.4709022 12.8959478 13.080022 10.4858569 1.8521457 1.0491782 -0.3186475 0.4930750 0.606300 0.353175 -0.253125 0.158941620 0.001757148 FALSE TRUE
ENST00000530455 ENSG00000182307 No_inf pgKDN_inf C8orf33 protein_coding retained_intron 26.73889 21.43358 29.71028 0.363717 0.3160231 0.4709022 12.3004881 5.363279 18.6159602 0.9287567 1.1940783 1.7934402 0.4408667 0.251300 0.626400 0.375100 0.001757148 0.001757148 FALSE FALSE
MSTRG.28408.1 ENSG00000182307 No_inf pgKDN_inf C8orf33 protein_coding   26.73889 21.43358 29.71028 0.363717 0.3160231 0.4709022 0.5936184 1.391299 0.2261504 1.3912988 0.2261504 -2.5689869 0.0270500 0.068125 0.007550 -0.060575 0.989996417 0.001757148 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000182307 E001 1.9498696 0.0073740845 9.519127e-01 0.987905486 8 145052420 145052464 45 + 0.464 0.473 0.047
ENSG00000182307 E002 1.9498696 0.0073740845 9.519127e-01 0.987905486 8 145052465 145052466 2 + 0.464 0.473 0.047
ENSG00000182307 E003 1.9498696 0.0073740845 9.519127e-01 0.987905486 8 145052467 145052467 1 + 0.464 0.473 0.047
ENSG00000182307 E004 5.5164904 0.0151404283 1.934290e-01 0.473167711 8 145052468 145052497 30 + 0.737 0.890 0.602
ENSG00000182307 E005 5.4798203 0.0026464618 9.155683e-01 0.973531414 8 145052498 145052585 88 + 0.814 0.803 -0.043
ENSG00000182307 E006 21.5487121 0.0006738726 2.363598e-02 0.140564891 8 145052586 145052746 161 + 1.409 1.267 -0.494
ENSG00000182307 E007 31.4454932 0.0005575712 8.952842e-01 0.965416269 8 145052747 145052897 151 + 1.505 1.513 0.027
ENSG00000182307 E008 0.1265070 0.0122743374 4.041061e-01   8 145052898 145052936 39 + 0.000 0.108 9.585
ENSG00000182307 E009 20.4906143 0.0007637656 8.989667e-02 0.311463692 8 145053062 145053146 85 + 1.375 1.267 -0.378
ENSG00000182307 E010 32.1275857 0.0010663254 1.792448e-04 0.003822613 8 145053297 145053443 147 + 1.596 1.398 -0.681
ENSG00000182307 E011 0.1268540 0.0122852935 4.040695e-01   8 145053444 145054017 574 + 0.000 0.108 9.585
ENSG00000182307 E012 25.9403800 0.0006109788 3.232717e-02 0.170200482 8 145054018 145054141 124 + 1.478 1.356 -0.422
ENSG00000182307 E013 229.4488670 0.0001477998 4.920994e-05 0.001311957 8 145054142 145056123 1982 + 2.336 2.389 0.177
ENSG00000182307 E014 0.3732278 0.1356996950 4.563846e-01   8 145061228 145061257 30 + 0.084 0.194 1.410
ENSG00000182307 E015 0.4908585 0.0738078308 7.915726e-01   8 145061258 145061311 54 + 0.154 0.194 0.410
ENSG00000182307 E016 0.2448930 0.0162518436 8.270530e-01   8 145065708 145065714 7 + 0.084 0.108 0.410
ENSG00000182307 E017 2.0010448 0.0093823089 1.990994e-03 0.025494369 8 145065715 145066685 971 + 0.214 0.669 2.525

Help

Please Click HERE to learn more details about the results from DEXseq.