ENSG00000182446

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000574964 ENSG00000182446 No_inf pgKDN_inf NPLOC4 protein_coding protein_coding_CDS_not_defined 43.12926 43.46985 41.94467 4.050092 1.256752 -0.05151523 2.371761 2.193666 2.4249627 1.6268924 0.8804849 0.1439938 0.05658333 0.055625 0.059000 0.003375 0.836283136 0.002936334 TRUE FALSE
ENST00000576940 ENSG00000182446 No_inf pgKDN_inf NPLOC4 protein_coding protein_coding_CDS_not_defined 43.12926 43.46985 41.94467 4.050092 1.256752 -0.05151523 1.645134 4.935401 0.0000000 2.8645356 0.0000000 -8.9499438 0.03335000 0.100050 0.000000 -0.100050 0.465299581 0.002936334   FALSE
ENST00000705719 ENSG00000182446 No_inf pgKDN_inf NPLOC4 protein_coding protein_coding 43.12926 43.46985 41.94467 4.050092 1.256752 -0.05151523 21.741792 11.113821 32.6299198 4.8754192 1.6668509 1.5529850 0.52429167 0.286200 0.782775 0.496575 0.320462543 0.002936334 FALSE TRUE
MSTRG.13459.1 ENSG00000182446 No_inf pgKDN_inf NPLOC4 protein_coding   43.12926 43.46985 41.94467 4.050092 1.256752 -0.05151523 7.899234 14.433745 0.0000000 5.2303351 0.0000000 -10.4962292 0.17138333 0.312225 0.000000 -0.312225 0.002936334 0.002936334 FALSE TRUE
MSTRG.13459.10 ENSG00000182446 No_inf pgKDN_inf NPLOC4 protein_coding   43.12926 43.46985 41.94467 4.050092 1.256752 -0.05151523 2.233940 3.289348 1.3248113 0.2262371 0.2701022 -1.3055451 0.05252500 0.077925 0.032275 -0.045650 0.420420990 0.002936334 TRUE TRUE
MSTRG.13459.4 ENSG00000182446 No_inf pgKDN_inf NPLOC4 protein_coding   43.12926 43.46985 41.94467 4.050092 1.256752 -0.05151523 2.005427 3.409845 0.7976219 0.4912493 0.5308685 -2.0821788 0.04815833 0.083750 0.018300 -0.065450 0.255797764 0.002936334 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000182446 E001 0.5076982 0.1876095224 7.880320e-02 2.877376e-01 17 81556866 81556886 21 - 0.000 0.294 10.734
ENSG00000182446 E002 2.4854550 0.0491327275 1.247380e-01 3.743719e-01 17 81556887 81556898 12 - 0.396 0.642 1.183
ENSG00000182446 E003 390.4431281 0.0007888639 1.074511e-02 8.422128e-02 17 81556899 81558788 1890 - 2.569 2.612 0.143
ENSG00000182446 E004 51.6048825 0.0003518675 9.608656e-01 9.912458e-01 17 81558789 81559013 225 - 1.719 1.722 0.008
ENSG00000182446 E005 20.8528837 0.0006866589 8.320367e-01 9.393199e-01 17 81559014 81559063 50 - 1.329 1.347 0.062
ENSG00000182446 E006 16.8480255 0.0008218187 2.916706e-01 5.851242e-01 17 81559064 81559090 27 - 1.208 1.287 0.277
ENSG00000182446 E007 20.3915030 0.0006706265 4.014133e-01 6.845692e-01 17 81559091 81559124 34 - 1.298 1.357 0.204
ENSG00000182446 E008 22.4534405 0.0007644979 5.810241e-01 8.132919e-01 17 81559125 81559181 57 - 1.349 1.388 0.134
ENSG00000182446 E009 26.9540565 0.0009821190 9.899052e-01 1.000000e+00 17 81559182 81559267 86 - 1.444 1.448 0.013
ENSG00000182446 E010 25.0721273 0.0005772493 4.485377e-01 7.225206e-01 17 81559268 81559315 48 - 1.436 1.396 -0.138
ENSG00000182446 E011 30.7422633 0.0006807029 4.031076e-02 1.946741e-01 17 81559316 81559395 80 - 1.553 1.448 -0.362
ENSG00000182446 E012 18.3352883 0.0064982114 5.076701e-03 5.021214e-02 17 81559396 81559416 21 - 1.382 1.176 -0.721
ENSG00000182446 E013 6.7133996 0.0021166399 4.104316e-03 4.323480e-02 17 81560562 81560629 68 - 0.696 1.007 1.208
ENSG00000182446 E014 8.8770491 0.0015655225 1.437228e-06 6.358938e-05 17 81560630 81560720 91 - 0.674 1.162 1.861
ENSG00000182446 E015 52.5659550 0.0002830547 1.713247e-21 5.310473e-19 17 81560721 81561765 1045 - 1.459 1.880 1.429
ENSG00000182446 E016 12.1117150 0.0168542198 1.122771e-05 3.774991e-04 17 81561766 81562106 341 - 0.827 1.276 1.646
ENSG00000182446 E017 25.7190372 0.0022275538 9.321434e-14 1.396506e-11 17 81562107 81563412 1306 - 1.103 1.595 1.719
ENSG00000182446 E018 4.8769450 0.0029825631 2.623887e-04 5.216245e-03 17 81563413 81563568 156 - 0.475 0.929 1.915
ENSG00000182446 E019 9.4796844 0.0416116789 5.939361e-04 9.994805e-03 17 81563569 81563920 352 - 0.738 1.176 1.648
ENSG00000182446 E020 3.8426915 0.0196481450 7.609374e-02 2.819104e-01 17 81563921 81563979 59 - 0.542 0.783 1.031
ENSG00000182446 E021 3.7416894 0.0292491297 8.365131e-03 7.126624e-02 17 81563980 81564212 233 - 0.437 0.816 1.677
ENSG00000182446 E022 1.9849693 0.0122089762 1.578602e-01 4.246362e-01 17 81564213 81564246 34 - 0.350 0.563 1.098
ENSG00000182446 E023 12.0162255 0.0011260020 3.551229e-09 2.744011e-07 17 81564247 81564908 662 - 0.757 1.292 1.979
ENSG00000182446 E024 12.0730782 0.0019873828 2.880314e-05 8.378128e-04 17 81564909 81565504 596 - 0.887 1.253 1.335
ENSG00000182446 E025 24.1325775 0.0021807212 4.216161e-02 1.998720e-01 17 81565505 81565607 103 - 1.459 1.338 -0.421
ENSG00000182446 E026 0.0000000       17 81566388 81566470 83 -      
ENSG00000182446 E027 0.2444846 0.0164720609 9.766668e-01   17 81566471 81566635 165 - 0.096 0.094 -0.040
ENSG00000182446 E028 0.0000000       17 81566875 81566985 111 -      
ENSG00000182446 E029 26.2021851 0.0005187960 4.120966e-05 1.130520e-03 17 81567417 81567533 117 - 1.541 1.308 -0.805
ENSG00000182446 E030 0.0000000       17 81567934 81567953 20 -      
ENSG00000182446 E031 0.0000000       17 81567954 81568075 122 -      
ENSG00000182446 E032 30.9893205 0.0004969760 1.054584e-04 2.477490e-03 17 81569016 81569111 96 - 1.599 1.396 -0.696
ENSG00000182446 E033 25.5603517 0.0006107179 5.957067e-03 5.618895e-02 17 81572017 81572088 72 - 1.499 1.342 -0.539
ENSG00000182446 E034 0.1176306 0.0117517763 5.184559e-01   17 81572089 81572108 20 - 0.096 0.000 -12.394
ENSG00000182446 E035 0.6351783 0.0328521315 2.426764e-02 1.427786e-01 17 81588091 81588187 97 - 0.000 0.344 13.693
ENSG00000182446 E036 30.7885373 0.0005306463 4.040717e-03 4.273260e-02 17 81588944 81589104 161 - 1.574 1.425 -0.511
ENSG00000182446 E037 21.0606845 0.0091286881 4.815314e-02 2.159923e-01 17 81596116 81596242 127 - 1.412 1.270 -0.494
ENSG00000182446 E038 17.1443545 0.0009718736 8.034066e-03 6.932301e-02 17 81597245 81597316 72 - 1.344 1.162 -0.642
ENSG00000182446 E039 0.0000000       17 81597317 81597319 3 -      
ENSG00000182446 E040 21.7969719 0.0006573365 1.578401e-02 1.087778e-01 17 81600341 81600427 87 - 1.428 1.281 -0.511
ENSG00000182446 E041 13.2922407 0.0019767509 1.087964e-01 3.462660e-01 17 81604548 81604571 24 - 1.214 1.092 -0.439
ENSG00000182446 E042 15.0215398 0.0029347529 2.465403e-01 5.371550e-01 17 81604572 81604608 37 - 1.246 1.162 -0.299
ENSG00000182446 E043 18.1138033 0.0007838501 5.752847e-03 5.475182e-02 17 81604609 81604663 55 - 1.368 1.183 -0.649
ENSG00000182446 E044 20.1701748 0.0006728100 4.003716e-03 4.244415e-02 17 81604664 81604727 64 - 1.412 1.229 -0.639
ENSG00000182446 E045 24.7493304 0.0005533006 8.963583e-05 2.172773e-03 17 81606691 81606814 124 - 1.515 1.287 -0.792
ENSG00000182446 E046 14.7537324 0.0009533989 1.261309e-04 2.867936e-03 17 81608728 81608800 73 - 1.324 1.037 -1.022
ENSG00000182446 E047 7.2679396 0.0304292596 5.792271e-02 2.409010e-01 17 81608801 81608810 10 - 1.018 0.800 -0.828
ENSG00000182446 E048 7.8642129 0.0466383806 4.871012e-02 2.174701e-01 17 81608811 81608822 12 - 1.058 0.816 -0.908
ENSG00000182446 E049 0.2459004 0.0166438699 9.768678e-01   17 81608823 81608919 97 - 0.096 0.094 -0.040
ENSG00000182446 E050 12.7248662 0.0600362109 3.322204e-02 1.732545e-01 17 81610210 81610258 49 - 1.246 1.007 -0.859
ENSG00000182446 E051 0.3627784 0.0166992215 5.602673e-01   17 81612679 81612873 195 - 0.175 0.094 -1.040
ENSG00000182446 E052 0.0000000       17 81613050 81613125 76 -      
ENSG00000182446 E053 28.6432199 0.0097893800 4.642215e-02 2.114103e-01 17 81613318 81613494 177 - 1.535 1.405 -0.448
ENSG00000182446 E054 0.0000000       17 81614318 81614381 64 -      
ENSG00000182446 E055 20.1392466 0.0006911081 1.604356e-01 4.282374e-01 17 81622166 81622278 113 - 1.368 1.281 -0.303
ENSG00000182446 E056 0.3817870 0.6082163025 3.291008e-01   17 81623673 81623706 34 - 0.000 0.237 12.001
ENSG00000182446 E057 19.3963156 0.0006779501 1.139545e-01 3.555080e-01 17 81629725 81629805 81 - 1.359 1.259 -0.349
ENSG00000182446 E058 0.0000000       17 81629864 81629875 12 -      
ENSG00000182446 E059 0.0000000       17 81636397 81636478 82 -      
ENSG00000182446 E060 19.9698672 0.0015446670 1.720480e-02 1.147568e-01 17 81636916 81637112 197 - 1.395 1.241 -0.537
ENSG00000182446 E061 0.0000000       17 81648430 81648465 36 -      

Help

Please Click HERE to learn more details about the results from DEXseq.