ENSG00000182511

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000328850 ENSG00000182511 No_inf pgKDN_inf FES protein_coding protein_coding 23.8396 57.13863 9.297135 0.7422126 1.349814 -2.61831 3.9449949 10.7260379 0.8771728 3.6900467 0.8771728 -3.5971026 0.12800000 0.187675 0.137775 -0.049900 0.5319205531 0.0008791194 FALSE TRUE
ENST00000394300 ENSG00000182511 No_inf pgKDN_inf FES protein_coding protein_coding 23.8396 57.13863 9.297135 0.7422126 1.349814 -2.61831 4.6079458 11.5420068 1.1543302 3.7721360 0.6935744 -3.3105714 0.17854167 0.202425 0.105975 -0.096450 0.7051559969 0.0008791194 FALSE TRUE
ENST00000414248 ENSG00000182511 No_inf pgKDN_inf FES protein_coding protein_coding 23.8396 57.13863 9.297135 0.7422126 1.349814 -2.61831 2.5517190 6.5614502 0.8119314 2.3147566 0.8119314 -2.9991220 0.08979167 0.115150 0.089200 -0.025950 0.6740744479 0.0008791194 FALSE TRUE
ENST00000444422 ENSG00000182511 No_inf pgKDN_inf FES protein_coding protein_coding 23.8396 57.13863 9.297135 0.7422126 1.349814 -2.61831 1.2432987 3.3376366 0.0000000 3.3376366 0.0000000 -8.3869991 0.05262500 0.058775 0.000000 -0.058775 1.0000000000 0.0008791194 FALSE TRUE
ENST00000452243 ENSG00000182511 No_inf pgKDN_inf FES protein_coding protein_coding 23.8396 57.13863 9.297135 0.7422126 1.349814 -2.61831 1.0767265 1.6722850 1.3605069 1.6722850 1.3605069 -0.2957126 0.06015000 0.029450 0.105450 0.076000 0.8281822190 0.0008791194 FALSE FALSE
ENST00000481665 ENSG00000182511 No_inf pgKDN_inf FES protein_coding retained_intron 23.8396 57.13863 9.297135 0.7422126 1.349814 -2.61831 2.1840076 6.3344840 0.2175389 1.9202607 0.2175389 -4.8013180 0.04854167 0.111450 0.034175 -0.077275 0.3514706145 0.0008791194 FALSE TRUE
ENST00000559355 ENSG00000182511 No_inf pgKDN_inf FES protein_coding protein_coding 23.8396 57.13863 9.297135 0.7422126 1.349814 -2.61831 0.4514902 0.5134506 0.8410198 0.3081861 0.8410198 0.7011393 0.03481667 0.009050 0.095400 0.086350 0.9371261641 0.0008791194 FALSE FALSE
MSTRG.10195.4 ENSG00000182511 No_inf pgKDN_inf FES protein_coding   23.8396 57.13863 9.297135 0.7422126 1.349814 -2.61831 0.8865569 0.0000000 1.9144903 0.0000000 0.7982461 7.5883326 0.10709167 0.000000 0.198700 0.198700 0.0008791194 0.0008791194 FALSE TRUE
MSTRG.10195.5 ENSG00000182511 No_inf pgKDN_inf FES protein_coding   23.8396 57.13863 9.297135 0.7422126 1.349814 -2.61831 1.4313246 2.5990394 0.6303061 1.7229487 0.6303061 -2.0266851 0.09689167 0.044625 0.069250 0.024625 1.0000000000 0.0008791194 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000182511 E001 0.0000000       15 90883695 90884043 349 +      
ENSG00000182511 E002 0.3802150 0.0280605132 1.000000e+00   15 90884447 90884465 19 + 0.000 0.103 9.267
ENSG00000182511 E003 0.7523703 0.0140876244 6.863379e-01 0.87043403 15 90884466 90884468 3 + 0.223 0.161 -0.582
ENSG00000182511 E004 2.6289568 0.0054838359 3.284940e-01 0.62101625 15 90884469 90884503 35 + 0.566 0.402 -0.817
ENSG00000182511 E005 4.2553271 0.0034474172 1.376821e-01 0.39499900 15 90884504 90884522 19 + 0.755 0.533 -0.957
ENSG00000182511 E006 4.7532044 0.0033485200 1.001829e-01 0.33075665 15 90884523 90884544 22 + 0.803 0.566 -0.997
ENSG00000182511 E007 1.4982880 0.0092679987 2.042739e-01 0.48710360 15 90884545 90884639 95 + 0.478 0.257 -1.319
ENSG00000182511 E008 0.6268712 0.0149820296 5.413415e-01 0.78901502 15 90884713 90884903 191 + 0.223 0.133 -0.904
ENSG00000182511 E009 3.3913374 0.0089546707 6.236359e-01 0.83794670 15 90885037 90885041 5 + 0.566 0.485 -0.381
ENSG00000182511 E010 3.7798297 0.0403536752 7.972745e-01 0.92348622 15 90885042 90885045 4 + 0.478 0.533 0.266
ENSG00000182511 E011 23.5664756 0.0026416927 1.025669e-02 0.08165079 15 90885046 90885258 213 + 1.376 1.170 -0.725
ENSG00000182511 E012 2.9065201 0.0644906492 2.630329e-01 0.55591586 15 90885259 90885339 81 + 0.223 0.472 1.555
ENSG00000182511 E013 1.8938287 0.0548552543 5.651717e-01 0.80411578 15 90885340 90885411 72 + 0.223 0.353 0.903
ENSG00000182511 E014 17.7315301 0.0007918005 8.854931e-05 0.00215127 15 90885412 90885585 174 + 1.364 1.031 -1.180
ENSG00000182511 E015 14.2986654 0.0012010627 1.107492e-01 0.34929663 15 90886961 90887057 97 + 1.137 0.978 -0.582
ENSG00000182511 E016 25.2757695 0.0040331437 5.764822e-01 0.81052750 15 90887187 90887370 184 + 1.265 1.222 -0.153
ENSG00000182511 E017 1.9063245 0.0208144182 1.405235e-01 0.39887357 15 90889206 90889305 100 + 0.000 0.370 13.294
ENSG00000182511 E018 9.8734093 0.0014225944 1.373140e-02 0.09876141 15 90889306 90889347 42 + 0.478 0.887 1.740
ENSG00000182511 E019 16.4011139 0.0180419975 2.840063e-01 0.57772563 15 90889348 90889423 76 + 0.923 1.066 0.531
ENSG00000182511 E020 11.0942649 0.0499379164 5.662103e-01 0.80460915 15 90889424 90889443 20 + 0.803 0.911 0.417
ENSG00000182511 E021 0.5072867 0.0693601044 1.000000e+00 1.00000000 15 90889444 90889516 73 + 0.000 0.133 11.662
ENSG00000182511 E022 10.7188301 0.0145825506 5.283011e-01 0.78006035 15 90889517 90889549 33 + 0.803 0.897 0.363
ENSG00000182511 E023 13.8809103 0.0013118696 3.835102e-01 0.66959130 15 90889550 90889636 87 + 0.886 0.998 0.418
ENSG00000182511 E024 8.5909033 0.0016316348 2.391512e-01 0.52812261 15 90889840 90889848 9 + 0.638 0.822 0.751
ENSG00000182511 E025 23.0684771 0.0040439301 5.952077e-01 0.82202070 15 90889849 90889962 114 + 1.137 1.195 0.206
ENSG00000182511 E026 29.4690719 0.0011859560 9.587297e-01 0.99019773 15 90890092 90890278 187 + 1.281 1.290 0.035
ENSG00000182511 E027 1.0067992 0.0409115920 1.000000e+00 1.00000000 15 90890366 90890400 35 + 0.223 0.211 -0.097
ENSG00000182511 E028 17.1608221 0.0011758486 1.715546e-01 0.44411194 15 90890401 90890484 84 + 0.923 1.086 0.602
ENSG00000182511 E029 1.0154579 0.0142996033 4.730452e-01 0.74015718 15 90890485 90890525 41 + 0.000 0.234 12.551
ENSG00000182511 E030 11.1067605 0.0012434091 2.535693e-01 0.54512488 15 90890982 90891055 74 + 0.755 0.916 0.628
ENSG00000182511 E031 16.1481791 0.0099260558 2.908177e-01 0.58435425 15 90891056 90891181 126 + 0.923 1.059 0.507
ENSG00000182511 E032 9.8228477 0.0109326983 9.876325e-01 0.99983114 15 90891182 90891191 10 + 0.847 0.856 0.035
ENSG00000182511 E033 2.0312292 0.0073871318 1.165659e-01 0.36016956 15 90891500 90891553 54 + 0.000 0.386 13.368
ENSG00000182511 E034 25.9317016 0.0231325498 7.908778e-01 0.91986924 15 90891554 90891676 123 + 1.249 1.235 -0.048
ENSG00000182511 E035 22.9081441 0.0009169608 8.508715e-01 0.94721462 15 90892058 90892111 54 + 1.197 1.185 -0.042
ENSG00000182511 E036 6.8160602 0.0021065032 3.019877e-01 0.59520580 15 90892112 90892409 298 + 0.566 0.738 0.740
ENSG00000182511 E037 32.5968758 0.0034649390 8.684899e-01 0.95483711 15 90892707 90892825 119 + 1.338 1.330 -0.025
ENSG00000182511 E038 21.7099248 0.0018474403 1.310770e-01 0.38406630 15 90893100 90893157 58 + 1.016 1.180 0.592
ENSG00000182511 E039 17.8264648 0.0007498935 1.427765e-02 0.10157822 15 90893158 90893194 37 + 0.803 1.111 1.151
ENSG00000182511 E040 0.2537694 0.0161218232 1.000000e+00   15 90893272 90893290 19 + 0.000 0.071 10.782
ENSG00000182511 E041 29.6450550 0.0004917803 2.501195e-01 0.54104773 15 90893291 90893414 124 + 1.197 1.302 0.371
ENSG00000182511 E042 32.3434419 0.0004408006 6.826359e-01 0.86858482 15 90893654 90893811 158 + 1.351 1.325 -0.090
ENSG00000182511 E043 27.8893053 0.0005228547 9.459000e-02 0.32000748 15 90893936 90894058 123 + 1.376 1.251 -0.437
ENSG00000182511 E044 37.6137076 0.0004009441 4.450812e-01 0.71953250 15 90895416 90895776 361 + 1.433 1.385 -0.167

Help

Please Click HERE to learn more details about the results from DEXseq.