ENSG00000182534

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355797 ENSG00000182534 No_inf pgKDN_inf MXRA7 protein_coding protein_coding 22.3673 17.74579 23.65092 0.6670016 2.362815 0.4142167 1.0954405 1.304861 1.084017 0.07757115 0.07012787 -0.2652752 0.05213333 0.074250 0.047400 -0.026850 0.8240598313 0.0006179867 FALSE TRUE
ENST00000375036 ENSG00000182534 No_inf pgKDN_inf MXRA7 protein_coding protein_coding 22.3673 17.74579 23.65092 0.6670016 2.362815 0.4142167 1.6332554 2.901398 0.000000 1.20578524 0.00000000 -8.1855682 0.07896667 0.158375 0.000000 -0.158375 0.0006179867 0.0006179867 FALSE TRUE
ENST00000449428 ENSG00000182534 No_inf pgKDN_inf MXRA7 protein_coding protein_coding 22.3673 17.74579 23.65092 0.6670016 2.362815 0.4142167 18.7419205 13.346000 20.159102 0.80376699 1.19020604 0.5946589 0.83455833 0.756525 0.863950 0.107425 0.5522403217 0.0006179867 FALSE TRUE
ENST00000588114 ENSG00000182534 No_inf pgKDN_inf MXRA7 protein_coding protein_coding 22.3673 17.74579 23.65092 0.6670016 2.362815 0.4142167 0.7617332 0.000000 2.285200 0.00000000 1.34385555 7.8424759 0.02779167 0.000000 0.083375 0.083375 0.4780192312 0.0006179867   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000182534 E001 28.0145181 0.0197422342 0.080889295 0.2922829 17 76672551 76677702 5152 - 1.395 1.524 0.442
ENSG00000182534 E002 0.0000000       17 76679566 76679568 3 -      
ENSG00000182534 E003 0.0000000       17 76679569 76679570 2 -      
ENSG00000182534 E004 41.8379230 0.0006588363 0.484382322 0.7485691 17 76679571 76680533 963 - 1.614 1.650 0.121
ENSG00000182534 E005 15.7329994 0.0009710426 0.587768911 0.8170501 17 76680534 76680616 83 - 1.237 1.208 -0.103
ENSG00000182534 E006 24.3232586 0.0007780883 0.055382515 0.2344592 17 76680617 76680776 160 - 1.448 1.351 -0.336
ENSG00000182534 E007 15.5390553 0.0102937788 0.055756769 0.2352856 17 76680777 76680879 103 - 1.281 1.140 -0.500
ENSG00000182534 E008 1.3862900 0.0097886871 0.002177373 0.0272091 17 76683847 76683927 81 - 0.090 0.558 3.511
ENSG00000182534 E009 10.2860133 0.0019729852 0.604483081 0.8274518 17 76685072 76685165 94 - 1.026 1.078 0.189
ENSG00000182534 E010 3.6511710 0.0428606979 0.690996535 0.8732007 17 76688113 76688176 64 - 0.690 0.643 -0.198
ENSG00000182534 E011 0.4904501 0.0158563525 0.911187634   17 76688177 76688669 493 - 0.164 0.183 0.189
ENSG00000182534 E012 0.7177503 0.0135505127 0.120653065 0.3674159 17 76688670 76690219 1550 - 0.332 0.101 -2.133
ENSG00000182534 E013 0.1272623 0.0125791622 0.481055078   17 76709498 76709597 100 - 0.000 0.101 8.920
ENSG00000182534 E014 3.3036774 0.0831092329 0.979558039 0.9975919 17 76710605 76711013 409 - 0.624 0.643 0.082

Help

Please Click HERE to learn more details about the results from DEXseq.