ENSG00000182541

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000331728 ENSG00000182541 No_inf pgKDN_inf LIMK2 protein_coding protein_coding 16.31001 14.60713 16.50079 1.235884 0.6474695 0.1757488 2.039129 1.249818 1.4599289 1.2498177 0.8519024 0.22253139 0.12627500 0.104850 0.083675 -0.021175 0.82818222 0.02694591 FALSE TRUE
ENST00000406516 ENSG00000182541 No_inf pgKDN_inf LIMK2 protein_coding protein_coding 16.31001 14.60713 16.50079 1.235884 0.6474695 0.1757488 1.006716 0.000000 3.0201482 0.0000000 1.0803288 8.24324455 0.05860833 0.000000 0.175825 0.175825 0.02694591 0.02694591 FALSE TRUE
ENST00000467301 ENSG00000182541 No_inf pgKDN_inf LIMK2 protein_coding protein_coding_CDS_not_defined 16.31001 14.60713 16.50079 1.235884 0.6474695 0.1757488 3.972138 5.174415 5.2639444 0.7792561 0.9538493 0.02470121 0.24868333 0.349000 0.314925 -0.034075 0.90759676 0.02694591   FALSE
ENST00000482270 ENSG00000182541 No_inf pgKDN_inf LIMK2 protein_coding retained_intron 16.31001 14.60713 16.50079 1.235884 0.6474695 0.1757488 1.008367 1.303310 0.3983715 0.3633030 0.2416947 -1.68525335 0.06179167 0.086450 0.022800 -0.063650 0.44335272 0.02694591 FALSE TRUE
MSTRG.19279.1 ENSG00000182541 No_inf pgKDN_inf LIMK2 protein_coding   16.31001 14.60713 16.50079 1.235884 0.6474695 0.1757488 1.244183 2.187199 0.9466425 0.3158353 0.2588392 -1.19961394 0.08032500 0.148750 0.058675 -0.090075 0.40299865 0.02694591 FALSE TRUE
MSTRG.19279.4 ENSG00000182541 No_inf pgKDN_inf LIMK2 protein_coding   16.31001 14.60713 16.50079 1.235884 0.6474695 0.1757488 1.624172 1.374695 0.5078961 0.5433943 0.5078961 -1.41883325 0.09738333 0.090075 0.034550 -0.055525 0.49163097 0.02694591 FALSE TRUE
MSTRG.19279.6 ENSG00000182541 No_inf pgKDN_inf LIMK2 protein_coding   16.31001 14.60713 16.50079 1.235884 0.6474695 0.1757488 4.734473 2.456995 4.3799406 1.0321462 1.8338069 0.83144681 0.28534167 0.164450 0.277300 0.112850 0.88414260 0.02694591 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000182541 E001 0.2541163 0.0161587857 0.2052395610   22 31212239 31212273 35 + 0.000 0.182 9.658
ENSG00000182541 E002 0.3728195 0.0166297393 0.5144539247   22 31212274 31212278 5 + 0.090 0.182 1.175
ENSG00000182541 E003 0.7450395 0.1412632217 0.4002635013 0.68378612 22 31212279 31212297 19 + 0.165 0.310 1.174
ENSG00000182541 E004 2.4683055 0.0090291937 0.2549597861 0.54686821 22 31212298 31212424 127 + 0.454 0.615 0.760
ENSG00000182541 E005 3.1042302 0.0049150649 0.0367716063 0.18460356 22 31225720 31225819 100 + 0.454 0.734 1.262
ENSG00000182541 E006 1.6972337 0.0080817158 0.3933244100 0.67820451 22 31235555 31235636 82 + 0.488 0.362 -0.673
ENSG00000182541 E007 0.0000000       22 31248358 31248401 44 +      
ENSG00000182541 E008 0.3729107 0.1992322813 0.5620560553   22 31248402 31248486 85 + 0.090 0.182 1.175
ENSG00000182541 E009 1.2345084 0.2272738460 0.5525830228 0.79611167 22 31248487 31248769 283 + 0.284 0.408 0.759
ENSG00000182541 E010 4.4627720 0.1285067303 0.1096020138 0.34748886 22 31258291 31258426 136 + 0.859 0.556 -1.259
ENSG00000182541 E011 5.2529636 0.0171673302 0.0001002973 0.00238196 22 31258427 31258958 532 + 0.488 0.981 2.049
ENSG00000182541 E012 1.6217102 0.0090916715 0.0298454966 0.16254378 22 31258959 31259099 141 + 0.228 0.556 1.912
ENSG00000182541 E013 0.7321333 0.0485484105 0.8938023773 0.96487935 22 31259100 31259120 21 + 0.228 0.250 0.175
ENSG00000182541 E014 4.9515972 0.0030837286 0.0461524067 0.21073348 22 31259121 31259230 110 + 0.872 0.642 -0.932
ENSG00000182541 E015 11.5037240 0.0011926761 0.7213861802 0.88784394 22 31259889 31260077 189 + 1.081 1.113 0.113
ENSG00000182541 E016 8.1834183 0.0016532829 0.8888057857 0.96291608 22 31262134 31262239 106 + 0.968 0.957 -0.041
ENSG00000182541 E017 11.2910439 0.0012966585 0.0630851005 0.25266834 22 31262595 31262791 197 + 1.157 1.004 -0.554
ENSG00000182541 E018 13.5612493 0.0011145169 0.9548481503 0.98899180 22 31265946 31266132 187 + 1.164 1.162 -0.008
ENSG00000182541 E019 9.7984292 0.0531144375 0.6970928254 0.87635441 22 31266984 31267070 87 + 0.999 1.067 0.246
ENSG00000182541 E020 12.3673569 0.0017694102 0.4959825147 0.75701914 22 31267776 31267907 132 + 1.098 1.154 0.203
ENSG00000182541 E021 7.4454322 0.0018477747 0.8498209326 0.94673419 22 31268144 31268200 57 + 0.935 0.918 -0.062
ENSG00000182541 E022 5.3966239 0.0027836097 0.4945864299 0.75596051 22 31271136 31271201 66 + 0.766 0.844 0.306
ENSG00000182541 E023 0.3802150 0.0294688919 0.0843821561   22 31272471 31272529 59 + 0.000 0.250 12.231
ENSG00000182541 E024 10.2853402 0.0014237589 0.5953686135 0.82207184 22 31272530 31272673 144 + 1.028 1.076 0.175
ENSG00000182541 E025 8.0257157 0.0019480054 0.3094737214 0.60278641 22 31272674 31272704 31 + 0.999 0.904 -0.356
ENSG00000182541 E026 0.2451451 0.0163710576 0.9286669537   22 31272845 31272916 72 + 0.090 0.100 0.175
ENSG00000182541 E027 10.6997039 0.0013632636 0.2385316658 0.52750776 22 31273452 31273507 56 + 1.113 1.015 -0.356
ENSG00000182541 E028 16.7604016 0.0024301937 0.0602675749 0.24636256 22 31275151 31275308 158 + 1.309 1.177 -0.463
ENSG00000182541 E029 1.6140049 0.0082324393 0.1105688993 0.34896267 22 31275309 31275665 357 + 0.284 0.524 1.345
ENSG00000182541 E030 9.5909134 0.0015161445 0.0994342647 0.32937524 22 31276789 31277638 850 + 1.090 0.945 -0.533
ENSG00000182541 E031 96.2237394 0.0001779148 0.5821266814 0.81387228 22 31278297 31280158 1862 + 1.980 1.996 0.054

Help

Please Click HERE to learn more details about the results from DEXseq.