ENSG00000182578

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000509861 ENSG00000182578 No_inf pgKDN_inf CSF1R protein_coding retained_intron 370.0315 107.3631 467.7468 1.79477 1.986976 2.123126 20.66915 12.12268 19.54869 1.919307 0.9007724 0.6889115 0.07023333 0.11225 0.041775 -0.070475 4.235328e-03 7.306347e-05   FALSE
ENST00000675795 ENSG00000182578 No_inf pgKDN_inf CSF1R protein_coding protein_coding 370.0315 107.3631 467.7468 1.79477 1.986976 2.123126 324.81556 82.87842 423.67706 3.698312 1.5592628 2.3537566 0.85091667 0.77225 0.905850 0.133600 7.306347e-05 7.306347e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000182578 E001 9.386249 6.381246e-03 1.792972e-01 4.543947e-01 5 150053291 150053294 4 - 0.898 1.044 0.542
ENSG00000182578 E002 1040.265852 7.495339e-05 1.220693e-17 2.644051e-15 5 150053295 150053837 543 - 2.902 2.996 0.313
ENSG00000182578 E003 954.447063 3.307305e-05 1.492106e-05 4.830448e-04 5 150053838 150054224 387 - 2.875 2.926 0.167
ENSG00000182578 E004 360.798885 7.267013e-05 6.804263e-01 8.681218e-01 5 150054322 150054430 109 - 2.462 2.472 0.031
ENSG00000182578 E005 15.194796 1.789281e-03 1.430646e-07 8.037550e-06 5 150054431 150054820 390 - 0.997 1.417 1.493
ENSG00000182578 E006 355.422137 4.616660e-04 6.361892e-02 2.538450e-01 5 150055237 150055336 100 - 2.449 2.490 0.134
ENSG00000182578 E007 325.212458 7.818447e-04 7.731520e-04 1.230427e-02 5 150056026 150056137 112 - 2.402 2.480 0.260
ENSG00000182578 E008 319.056530 6.120248e-04 3.725423e-01 6.604322e-01 5 150056219 150056341 123 - 2.407 2.428 0.072
ENSG00000182578 E009 252.886181 6.947079e-05 2.706186e-01 5.643181e-01 5 150057287 150057384 98 - 2.316 2.290 -0.085
ENSG00000182578 E010 223.103457 9.210270e-05 1.929724e-01 4.727798e-01 5 150057504 150057592 89 - 2.263 2.230 -0.108
ENSG00000182578 E011 2.314317 5.864919e-03 2.352652e-02 1.401767e-01 5 150058155 150058271 117 - 0.364 0.701 1.618
ENSG00000182578 E012 206.847078 1.159354e-03 8.758030e-02 3.067045e-01 5 150059700 150059777 78 - 2.234 2.183 -0.169
ENSG00000182578 E013 206.334933 4.427608e-04 4.763995e-02 2.146365e-01 5 150059778 150059862 85 - 2.233 2.179 -0.183
ENSG00000182578 E014 229.335415 5.193105e-04 7.553313e-01 9.035894e-01 5 150060862 150060972 111 - 2.270 2.263 -0.024
ENSG00000182578 E015 218.438979 2.463249e-03 6.761953e-01 8.658391e-01 5 150061491 150061595 105 - 2.244 2.259 0.049
ENSG00000182578 E016 2.269917 7.051837e-03 7.025657e-01 8.790058e-01 5 150061596 150061722 127 - 0.463 0.399 -0.337
ENSG00000182578 E017 211.780028 9.785563e-05 3.166125e-02 1.681279e-01 5 150061723 150061849 127 - 2.245 2.189 -0.188
ENSG00000182578 E018 3.402466 4.089084e-03 1.498853e-02 1.050268e-01 5 150067026 150067181 156 - 0.481 0.815 1.450
ENSG00000182578 E019 163.727766 1.051950e-04 1.951937e-03 2.510153e-02 5 150068215 150068330 116 - 2.141 2.046 -0.317
ENSG00000182578 E020 218.358748 8.767498e-04 2.854491e-03 3.326580e-02 5 150069873 150070063 191 - 2.263 2.177 -0.288
ENSG00000182578 E021 135.674815 1.404643e-04 9.650051e-02 3.235170e-01 5 150070182 150070302 121 - 2.053 1.998 -0.182
ENSG00000182578 E022 109.544446 1.404240e-04 3.195974e-01 6.122674e-01 5 150070456 150070539 84 - 1.957 1.922 -0.119
ENSG00000182578 E023 82.231121 2.077430e-04 1.705000e-01 4.426778e-01 5 150070540 150070571 32 - 1.838 1.781 -0.194
ENSG00000182578 E024 212.912378 8.499616e-05 3.853752e-03 4.137931e-02 5 150073301 150073493 193 - 2.251 2.174 -0.256
ENSG00000182578 E025 1.570222 1.064004e-01 3.515068e-01 6.417144e-01 5 150076904 150077275 372 - 0.316 0.479 0.908
ENSG00000182578 E026 219.447441 9.954371e-05 6.252235e-05 1.597385e-03 5 150077276 150077435 160 - 2.269 2.162 -0.356
ENSG00000182578 E027 198.544369 2.471376e-04 8.967739e-05 2.172803e-03 5 150078112 150078248 137 - 2.227 2.115 -0.374
ENSG00000182578 E028 263.810612 3.962079e-04 1.544150e-05 4.957274e-04 5 150080052 150080336 285 - 2.349 2.239 -0.367
ENSG00000182578 E029 230.928835 8.515097e-05 1.578276e-06 6.926181e-05 5 150080767 150081024 258 - 2.294 2.168 -0.420
ENSG00000182578 E030 104.406758 7.361078e-04 3.708721e-02 1.854842e-01 5 150086379 150086607 229 - 1.945 1.863 -0.276
ENSG00000182578 E031 0.117004 1.167373e-02 1.000000e+00   5 150113261 150113372 112 - 0.049 0.001 -6.441

Help

Please Click HERE to learn more details about the results from DEXseq.