ENSG00000182944

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000397938 ENSG00000182944 No_inf pgKDN_inf EWSR1 protein_coding protein_coding 132.1582 130.0339 129.13 1.791079 2.757228 -0.01006277 35.65175 25.27657 46.980368 1.938314 6.155403 0.8939938 0.2704500 0.194675 0.364325 0.169650 0.06098398 0.00115004 FALSE TRUE
ENST00000406548 ENSG00000182944 No_inf pgKDN_inf EWSR1 protein_coding protein_coding 132.1582 130.0339 129.13 1.791079 2.757228 -0.01006277 36.17967 23.58248 38.186818 2.182452 3.637374 0.6951254 0.2724667 0.181425 0.295475 0.114050 0.12387701 0.00115004 FALSE TRUE
ENST00000469669 ENSG00000182944 No_inf pgKDN_inf EWSR1 protein_coding retained_intron 132.1582 130.0339 129.13 1.791079 2.757228 -0.01006277 20.97173 31.32600 11.969326 1.404135 2.126485 -1.3872742 0.1588917 0.241050 0.092350 -0.148700 0.00115004 0.00115004 FALSE TRUE
MSTRG.19223.17 ENSG00000182944 No_inf pgKDN_inf EWSR1 protein_coding   132.1582 130.0339 129.13 1.791079 2.757228 -0.01006277 16.37807 25.77407 8.419469 2.211492 3.330991 -1.6129662 0.1237167 0.197825 0.064300 -0.133525 0.29199547 0.00115004 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000182944 E001 0.1272623 0.0123943497 6.824575e-01   22 29268004 29268008 5 + 0.000 0.085 8.525
ENSG00000182944 E002 0.1272623 0.0123943497 6.824575e-01   22 29268009 29268252 244 + 0.000 0.085 11.054
ENSG00000182944 E003 0.0000000       22 29268253 29268267 15 +      
ENSG00000182944 E004 0.0000000       22 29268268 29268272 5 +      
ENSG00000182944 E005 1.1064973 0.0174399950 9.802595e-01 9.977979e-01 22 29268273 29268281 9 + 0.324 0.318 -0.038
ENSG00000182944 E006 1.7131336 0.0233092530 6.678833e-01 8.618078e-01 22 29268282 29268289 8 + 0.468 0.400 -0.360
ENSG00000182944 E007 1.7131336 0.0233092530 6.678833e-01 8.618078e-01 22 29268290 29268290 1 + 0.468 0.400 -0.360
ENSG00000182944 E008 12.0835793 0.0022136643 2.478764e-06 1.021910e-04 22 29268291 29268312 22 + 1.298 0.898 -1.447
ENSG00000182944 E009 13.0633450 0.0012058578 3.041194e-06 1.220415e-04 22 29268313 29268315 3 + 1.321 0.943 -1.360
ENSG00000182944 E010 19.9833546 0.0009410480 1.218683e-07 6.970146e-06 22 29268316 29268325 10 + 1.487 1.131 -1.243
ENSG00000182944 E011 46.2749047 0.0050156020 1.215644e-07 6.960145e-06 22 29268326 29268349 24 + 1.811 1.527 -0.967
ENSG00000182944 E012 0.3808443 0.0319353844 1.609956e-01   22 29269223 29269662 440 + 0.000 0.217 12.443
ENSG00000182944 E013 56.0729929 0.0120453355 9.083096e-05 2.195821e-03 22 29272216 29272252 37 + 1.877 1.630 -0.833
ENSG00000182944 E014 44.0876001 0.0187063373 6.766427e-03 6.164377e-02 22 29272380 29272385 6 + 1.758 1.548 -0.711
ENSG00000182944 E015 49.7382119 0.0088963620 1.184429e-03 1.703039e-02 22 29272386 29272431 46 + 1.802 1.608 -0.657
ENSG00000182944 E016 1.3417872 0.1347855489 5.988343e-01 8.240431e-01 22 29273738 29273740 3 + 0.425 0.318 -0.623
ENSG00000182944 E017 43.4265858 0.0023745159 6.920958e-03 6.260901e-02 22 29273741 29273864 124 + 1.716 1.579 -0.465
ENSG00000182944 E018 0.0000000       22 29274265 29274267 3 +      
ENSG00000182944 E019 0.0000000       22 29274268 29274282 15 +      
ENSG00000182944 E020 0.0000000       22 29274283 29274453 171 +      
ENSG00000182944 E021 2.4807028 0.0531910663 2.434481e-01 5.334680e-01 22 29275629 29278029 2401 + 0.425 0.605 0.863
ENSG00000182944 E022 28.8701992 0.0027627609 5.814914e-01 8.135027e-01 22 29278030 29278130 101 + 1.491 1.454 -0.126
ENSG00000182944 E023 45.3094304 0.0005553758 2.377298e-02 1.411350e-01 22 29278131 29278216 86 + 1.718 1.613 -0.360
ENSG00000182944 E024 87.1779723 0.0001963501 6.406979e-04 1.057063e-02 22 29282390 29282557 168 + 2.002 1.888 -0.384
ENSG00000182944 E025 112.0574717 0.0001449382 1.261271e-05 4.173336e-04 22 29286923 29287134 212 + 2.117 1.989 -0.429
ENSG00000182944 E026 67.7014047 0.0002512189 1.956145e-03 2.514364e-02 22 29288606 29288755 150 + 1.896 1.778 -0.396
ENSG00000182944 E027 34.9182146 0.0103780738 1.850694e-01 4.626435e-01 22 29288756 29288786 31 + 1.600 1.510 -0.309
ENSG00000182944 E028 22.0912709 0.0006434974 1.159001e-03 1.676310e-02 22 29288787 29288986 200 + 1.225 1.434 0.726
ENSG00000182944 E029 14.0673245 0.0009392932 3.084939e-04 5.931662e-03 22 29288987 29289062 76 + 0.982 1.272 1.044
ENSG00000182944 E030 190.4975698 0.0004326027 8.999978e-36 6.934354e-33 22 29289063 29290412 1350 + 2.079 2.379 1.001
ENSG00000182944 E031 75.0912459 0.0031205343 7.643374e-08 4.565202e-06 22 29290413 29290829 417 + 1.730 1.957 0.767
ENSG00000182944 E032 156.0577889 0.0001530356 4.957696e-33 3.260834e-30 22 29290830 29291561 732 + 1.989 2.294 1.021
ENSG00000182944 E033 29.4751486 0.0007474668 1.855676e-01 4.633304e-01 22 29291562 29291564 3 + 1.437 1.507 0.240
ENSG00000182944 E034 67.1126726 0.0007196679 7.064823e-01 8.809224e-01 22 29291565 29291599 35 + 1.838 1.820 -0.063
ENSG00000182944 E035 63.5948762 0.0002318673 4.078698e-14 6.321279e-12 22 29291600 29291928 329 + 1.606 1.907 1.018
ENSG00000182944 E036 46.1905543 0.0003753386 2.621809e-07 1.387680e-05 22 29291929 29292136 208 + 1.517 1.752 0.800
ENSG00000182944 E037 75.1033157 0.0001933931 1.568584e-01 4.232539e-01 22 29292137 29292158 22 + 1.906 1.853 -0.180
ENSG00000182944 E038 69.1001776 0.0002109426 1.755626e-01 4.496316e-01 22 29292159 29292169 11 + 1.870 1.817 -0.180
ENSG00000182944 E039 62.4217822 0.0002547234 5.788795e-01 8.118088e-01 22 29292488 29292499 12 + 1.811 1.786 -0.086
ENSG00000182944 E040 136.4412439 0.0001277235 1.498224e-01 4.122715e-01 22 29292500 29292606 107 + 2.156 2.115 -0.139
ENSG00000182944 E041 2.2130430 0.0993035750 9.363696e-01 9.818623e-01 22 29295526 29296238 713 + 0.508 0.500 -0.038
ENSG00000182944 E042 157.2439835 0.0011753499 9.234171e-02 3.156159e-01 22 29296239 29296368 130 + 2.222 2.172 -0.168
ENSG00000182944 E043 134.8774843 0.0001306810 3.803852e-02 1.881311e-01 22 29297827 29297949 123 + 2.160 2.102 -0.194
ENSG00000182944 E044 63.6028821 0.0013244501 2.181896e-01 5.046460e-01 22 29298733 29298780 48 + 1.835 1.781 -0.181
ENSG00000182944 E045 113.7022990 0.0028366640 1.947546e-01 4.747307e-01 22 29298781 29298895 115 + 2.082 2.032 -0.166
ENSG00000182944 E046 8.1301533 0.0016871791 1.700248e-04 3.665115e-03 22 29298896 29299194 299 + 0.689 1.080 1.505
ENSG00000182944 E047 5.1241004 0.0027861070 3.446208e-03 3.829956e-02 22 29299195 29299233 39 + 0.543 0.898 1.470
ENSG00000182944 E048 78.1018548 0.0115461793 6.000728e-01 8.247937e-01 22 29299234 29299280 47 + 1.877 1.904 0.090
ENSG00000182944 E049 68.7584852 0.0006503460 2.886928e-01 5.822356e-01 22 29299281 29299331 51 + 1.817 1.853 0.120
ENSG00000182944 E050 7.1937992 0.0455187804 1.580345e-01 4.248123e-01 22 29299332 29299598 267 + 0.797 0.974 0.678
ENSG00000182944 E051 278.6739073 0.0010104864 3.654823e-01 6.540554e-01 22 29299599 29299851 253 + 2.454 2.431 -0.078
ENSG00000182944 E052 198.3078514 0.0002264451 1.061400e-02 8.350920e-02 22 29300122 29300525 404 + 2.327 2.268 -0.199

Help

Please Click HERE to learn more details about the results from DEXseq.