ENSG00000183431

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373019 ENSG00000183431 No_inf pgKDN_inf SF3A3 protein_coding protein_coding 49.47224 36.15403 60.73458 2.231638 1.647438 0.7482004 35.573521 28.259470 41.465227 0.683607 0.9038738 0.553005 0.7320167 0.794175 0.683875 -0.110300 0.59245015 0.04792073 FALSE TRUE
ENST00000462258 ENSG00000183431 No_inf pgKDN_inf SF3A3 protein_coding protein_coding_CDS_not_defined 49.47224 36.15403 60.73458 2.231638 1.647438 0.7482004 7.557884 2.710192 12.579153 2.710192 1.6798659 2.210401 0.1388250 0.066650 0.206525 0.139875 0.04792073 0.04792073 FALSE FALSE
ENST00000489537 ENSG00000183431 No_inf pgKDN_inf SF3A3 protein_coding protein_coding_CDS_not_defined 49.47224 36.15403 60.73458 2.231638 1.647438 0.7482004 2.476542 0.000000 3.373727 0.000000 1.9957743 8.402469 0.0449750 0.000000 0.056300 0.056300 0.56307960 0.04792073 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000183431 E001 0.2458395 0.0163275187 7.974058e-01   1 37956975 37956979 5 - 0.081 0.111 0.497
ENSG00000183431 E002 106.7776538 0.0026289325 2.614704e-07 1.385279e-05 1 37956980 37958062 1083 - 1.943 2.120 0.594
ENSG00000183431 E003 70.4995158 0.0045811361 2.915548e-01 5.850840e-01 1 37958063 37958263 201 - 1.827 1.879 0.177
ENSG00000183431 E004 30.1793358 0.0012765178 9.321787e-01 9.802761e-01 1 37960120 37960175 56 - 1.490 1.491 0.004
ENSG00000183431 E005 0.2537079 0.2756327084 1.992992e-01   1 37960176 37960693 518 - 0.000 0.199 11.759
ENSG00000183431 E006 33.8696636 0.0004247467 2.364983e-01 5.254790e-01 1 37968044 37968134 91 - 1.561 1.507 -0.187
ENSG00000183431 E007 27.6438512 0.0005286692 8.824090e-01 9.604482e-01 1 37969354 37969386 33 - 1.447 1.461 0.049
ENSG00000183431 E008 41.6205927 0.0003377221 8.253661e-01 9.367500e-01 1 37969387 37969464 78 - 1.627 1.623 -0.014
ENSG00000183431 E009 70.5050567 0.0004274484 2.042244e-02 1.286006e-01 1 37969571 37969735 165 - 1.882 1.805 -0.259
ENSG00000183431 E010 38.3195554 0.0127149817 7.292674e-01 8.920306e-01 1 37976884 37976953 70 - 1.597 1.582 -0.050
ENSG00000183431 E011 20.8614772 0.0037312128 1.887963e-01 4.673248e-01 1 37978720 37978722 3 - 1.370 1.286 -0.293
ENSG00000183431 E012 43.1739795 0.0003459028 6.293806e-01 8.410142e-01 1 37978723 37978827 105 - 1.648 1.632 -0.054
ENSG00000183431 E013 1.1252214 0.4213003463 1.512768e-01 4.146235e-01 1 37978828 37978987 160 - 0.150 0.482 2.303
ENSG00000183431 E014 16.0230450 0.0103152336 5.232933e-01 7.766548e-01 1 37978988 37978989 2 - 1.248 1.200 -0.170
ENSG00000183431 E015 21.8408805 0.0016054001 3.533814e-01 6.431308e-01 1 37978990 37979055 66 - 1.378 1.324 -0.188
ENSG00000183431 E016 0.2458395 0.0163275187 7.974058e-01   1 37979056 37979199 144 - 0.081 0.111 0.497
ENSG00000183431 E017 0.4896297 0.0157721776 7.430224e-01   1 37979391 37979464 74 - 0.150 0.199 0.497
ENSG00000183431 E018 24.5331575 0.0005801111 4.347717e-01 7.118575e-01 1 37979465 37979533 69 - 1.421 1.380 -0.141
ENSG00000183431 E019 42.2850671 0.0003312970 4.082569e-01 6.906378e-01 1 37980586 37980724 139 - 1.646 1.614 -0.108
ENSG00000183431 E020 0.1271363 0.0123590138 3.835167e-01   1 37980725 37980789 65 - 0.000 0.111 10.760
ENSG00000183431 E021 36.6255349 0.0107168999 9.048303e-01 9.695265e-01 1 37981729 37981811 83 - 1.571 1.572 0.004
ENSG00000183431 E022 0.0000000       1 37984118 37984168 51 -      
ENSG00000183431 E023 37.3940019 0.0004172222 7.571056e-01 9.044016e-01 1 37984169 37984260 92 - 1.571 1.592 0.072
ENSG00000183431 E024 28.8703169 0.0005685345 1.645410e-01 4.337981e-01 1 37984707 37984779 73 - 1.501 1.429 -0.246
ENSG00000183431 E025 42.4614471 0.0004214266 9.193089e-02 3.148771e-01 1 37987573 37987678 106 - 1.664 1.592 -0.244
ENSG00000183431 E026 27.0558751 0.0009145394 7.673638e-01 9.098844e-01 1 37987784 37987836 53 - 1.434 1.457 0.079
ENSG00000183431 E027 25.3960231 0.0005727150 3.682366e-01 6.567399e-01 1 37989548 37989595 48 - 1.437 1.390 -0.163
ENSG00000183431 E028 0.0000000       1 37989596 37989650 55 -      
ENSG00000183431 E029 34.6914413 0.0005395389 9.852251e-01 9.989951e-01 1 37989870 37990075 206 - 1.546 1.552 0.017

Help

Please Click HERE to learn more details about the results from DEXseq.