ENSG00000183569

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000327678 ENSG00000183569 No_inf pgKDN_inf SERHL2 protein_coding protein_coding 5.101766 9.16292 3.674247 0.6501212 0.9117767 -1.316011 1.2638384 3.7915151 0.00000000 0.7524459 0.00000000 -8.5704307 0.14153333 0.424600 0.000000 -0.424600 0.0007989456 0.0007989456 FALSE TRUE
ENST00000335879 ENSG00000183569 No_inf pgKDN_inf SERHL2 protein_coding protein_coding 5.101766 9.16292 3.674247 0.6501212 0.9117767 -1.316011 0.1226774 0.0000000 0.36803217 0.0000000 0.36803217 5.2404371 0.04319167 0.000000 0.129575 0.129575 0.7723747051 0.0007989456 FALSE TRUE
ENST00000340239 ENSG00000183569 No_inf pgKDN_inf SERHL2 protein_coding protein_coding 5.101766 9.16292 3.674247 0.6501212 0.9117767 -1.316011 0.1183566 0.0000000 0.35506986 0.0000000 0.35506986 5.1901007 0.02970000 0.000000 0.089100 0.089100 0.7138185105 0.0007989456 TRUE TRUE
ENST00000407614 ENSG00000183569 No_inf pgKDN_inf SERHL2 protein_coding protein_coding 5.101766 9.16292 3.674247 0.6501212 0.9117767 -1.316011 1.2939961 3.1402914 0.45056990 1.1672742 0.45056990 -2.7739933 0.17388333 0.326675 0.074325 -0.252350 0.5018781263 0.0007989456 FALSE TRUE
ENST00000416156 ENSG00000183569 No_inf pgKDN_inf SERHL2 protein_coding nonsense_mediated_decay 5.101766 9.16292 3.674247 0.6501212 0.9117767 -1.316011 0.2939331 0.3618819 0.07243792 0.3618819 0.07243792 -2.1734644 0.09310833 0.044950 0.040050 -0.004900 0.9326024378 0.0007989456 TRUE FALSE
ENST00000447870 ENSG00000183569 No_inf pgKDN_inf SERHL2 protein_coding protein_coding 5.101766 9.16292 3.674247 0.6501212 0.9117767 -1.316011 0.1681786 0.0000000 0.50453570 0.0000000 0.50453570 5.6851993 0.02774167 0.000000 0.083225 0.083225 0.6579637931 0.0007989456 FALSE FALSE
ENST00000477564 ENSG00000183569 No_inf pgKDN_inf SERHL2 protein_coding nonsense_mediated_decay 5.101766 9.16292 3.674247 0.6501212 0.9117767 -1.316011 0.1639466 0.0864700 0.00000000 0.0864700 0.00000000 -3.2700804 0.05419167 0.009125 0.000000 -0.009125 1.0000000000 0.0007989456 TRUE TRUE
ENST00000534080 ENSG00000183569 No_inf pgKDN_inf SERHL2 protein_coding retained_intron 5.101766 9.16292 3.674247 0.6501212 0.9117767 -1.316011 0.6034931 0.9899385 0.82054082 0.3377607 0.36844340 -0.2677883 0.13263333 0.106075 0.291825 0.185750 0.8276712122 0.0007989456 FALSE TRUE
MSTRG.19519.12 ENSG00000183569 No_inf pgKDN_inf SERHL2 protein_coding   5.101766 9.16292 3.674247 0.6501212 0.9117767 -1.316011 0.9502807 0.7928226 0.99870083 0.1264527 0.26539001 0.3293453 0.26327500 0.088550 0.274725 0.186175 0.3333298440 0.0007989456   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000183569 E001 0.0000000       22 42553617 42553713 97 +      
ENSG00000183569 E002 0.0000000       22 42553859 42553861 3 +      
ENSG00000183569 E003 0.0000000       22 42553862 42553884 23 +      
ENSG00000183569 E004 0.0000000       22 42553885 42553917 33 +      
ENSG00000183569 E005 0.2363338 0.015872930 0.051187611   22 42553918 42553934 17 + 0.260 0.000 -12.588
ENSG00000183569 E006 0.5902982 0.017129579 0.000862101 0.01337919 22 42553935 42553955 21 + 0.485 0.000 -13.911
ENSG00000183569 E007 2.0950045 0.008838940 0.246286501 0.53696953 22 42553956 42554014 59 + 0.588 0.391 -0.978
ENSG00000183569 E008 2.0029305 0.007699757 0.374995294 0.66263604 22 42554015 42554020 6 + 0.349 0.462 0.623
ENSG00000183569 E009 2.1294375 0.007699225 0.304566202 0.59798807 22 42554021 42554042 22 + 0.349 0.483 0.730
ENSG00000183569 E010 0.0000000       22 42554909 42554937 29 +      
ENSG00000183569 E011 1.8829714 0.008885915 0.166806312 0.43722019 22 42554938 42554951 14 + 0.260 0.462 1.208
ENSG00000183569 E012 1.8829714 0.008885915 0.166806312 0.43722019 22 42554952 42555087 136 + 0.260 0.462 1.208
ENSG00000183569 E013 0.0000000       22 42555232 42555345 114 +      
ENSG00000183569 E014 0.0000000       22 42555664 42555705 42 +      
ENSG00000183569 E015 0.0000000       22 42555706 42556047 342 +      
ENSG00000183569 E016 0.0000000       22 42556048 42556063 16 +      
ENSG00000183569 E017 0.0000000       22 42556064 42556083 20 +      
ENSG00000183569 E018 0.0000000       22 42556514 42556588 75 +      
ENSG00000183569 E019 1.3870156 0.011841677 0.121899402 0.36939510 22 42558348 42558457 110 + 0.149 0.391 1.830
ENSG00000183569 E020 2.2674036 0.006693718 0.072531342 0.27334955 22 42560186 42560228 43 + 0.260 0.523 1.508
ENSG00000183569 E021 2.0043495 0.007670202 0.371608746 0.65963068 22 42560229 42560265 37 + 0.349 0.462 0.623
ENSG00000183569 E022 1.2510041 0.160872093 0.599119177 0.82422441 22 42563389 42563481 93 + 0.260 0.336 0.509
ENSG00000183569 E023 2.7485092 0.037767798 0.579123440 0.81193802 22 42566304 42566338 35 + 0.485 0.542 0.273
ENSG00000183569 E024 2.9482977 0.005497257 0.054000293 0.23122037 22 42570650 42571120 471 + 0.742 0.462 -1.251
ENSG00000183569 E025 2.7405473 0.006781884 0.919780286 0.97502712 22 42571121 42571203 83 + 0.539 0.523 -0.077
ENSG00000183569 E026 1.8349778 0.009036900 0.037162455 0.18562968 22 42571204 42571358 155 + 0.632 0.306 -1.685
ENSG00000183569 E027 2.4740570 0.022091947 0.503165700 0.76270310 22 42571359 42571901 543 + 0.588 0.462 -0.599
ENSG00000183569 E028 0.0000000       22 42572436 42572529 94 +      
ENSG00000183569 E029 0.0000000       22 42573634 42573745 112 +      
ENSG00000183569 E030 0.0000000       22 42573936 42573938 3 +      
ENSG00000183569 E031 0.0000000       22 42573939 42574382 444 +      

Help

Please Click HERE to learn more details about the results from DEXseq.