ENSG00000183648

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000553666 ENSG00000183648 No_inf pgKDN_inf NDUFB1 protein_coding retained_intron 82.95959 80.00712 90.05485 2.446058 4.145366 0.1706554 5.308504 8.281898 3.262636 0.2215112 0.2606815 -1.341249 0.06533333 0.10400 0.036575 -0.067425 0.03373008 0.02236225    
ENST00000605997 ENSG00000183648 No_inf pgKDN_inf NDUFB1 protein_coding protein_coding 82.95959 80.00712 90.05485 2.446058 4.145366 0.1706554 73.077768 67.029159 82.412945 3.0980677 4.3538920 0.298042 0.87875833 0.83665 0.914450 0.077800 0.02236225 0.02236225 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000183648 E001 0.1176306 0.0118829014 4.530646e-01   14 92116122 92116122 1 - 0.103 0.000 -9.903
ENSG00000183648 E002 0.2363338 0.0158263999 1.891502e-01   14 92116123 92116125 3 - 0.185 0.000 -12.758
ENSG00000183648 E003 54.7610456 0.0003509869 6.762999e-01 8.658391e-01 14 92116126 92116229 104 - 1.751 1.737 -0.049
ENSG00000183648 E004 100.5593773 0.0001866708 2.023705e-03 2.577755e-02 14 92117498 92117642 145 - 2.041 1.972 -0.233
ENSG00000183648 E005 28.9973487 0.0005450571 3.813015e-09 2.929503e-07 14 92117643 92118726 1084 - 1.263 1.589 1.127
ENSG00000183648 E006 2.3131568 0.0585963676 3.364954e-01 6.284367e-01 14 92118849 92118966 118 - 0.594 0.447 -0.703
ENSG00000183648 E007 2.5217732 0.0062456944 5.441461e-04 9.328664e-03 14 92120331 92120416 86 - 0.185 0.703 2.927
ENSG00000183648 E008 1.1231766 0.0965310928 1.812576e-01 4.571054e-01 14 92121196 92121211 16 - 0.185 0.411 1.565
ENSG00000183648 E009 4.8202545 0.0059596781 3.639597e-01 6.526553e-01 14 92121212 92121641 430 - 0.699 0.806 0.435
ENSG00000183648 E010 32.4363352 0.0005708387 9.654019e-02 3.235509e-01 14 92121642 92121917 276 - 1.564 1.484 -0.276

Help

Please Click HERE to learn more details about the results from DEXseq.