ENSG00000183696

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000395560 ENSG00000183696 No_inf pgKDN_inf UPP1 protein_coding nonsense_mediated_decay 85.63833 26.25575 94.07924 1.994766 3.252306 1.840847 13.632418 2.018474 15.999351 0.9486814 5.638156 2.9804480 0.14061667 0.085550 0.170675 0.085125 0.83628314 0.01667749 FALSE TRUE
ENST00000395564 ENSG00000183696 No_inf pgKDN_inf UPP1 protein_coding protein_coding 85.63833 26.25575 94.07924 1.994766 3.252306 1.840847 31.634698 5.820437 40.808973 0.8687084 2.581747 2.8075639 0.33683333 0.219900 0.436600 0.216700 0.01667749 0.01667749 FALSE TRUE
ENST00000444999 ENSG00000183696 No_inf pgKDN_inf UPP1 protein_coding nonsense_mediated_decay 85.63833 26.25575 94.07924 1.994766 3.252306 1.840847 10.134931 3.936677 8.325963 1.4541530 3.833179 1.0787102 0.12025833 0.141975 0.085700 -0.056275 0.85429310 0.01667749 FALSE FALSE
ENST00000495446 ENSG00000183696 No_inf pgKDN_inf UPP1 protein_coding retained_intron 85.63833 26.25575 94.07924 1.994766 3.252306 1.840847 3.746175 1.969979 1.702442 1.3039528 1.011884 -0.2094299 0.04815833 0.071825 0.017050 -0.054775 0.84887737 0.01667749 FALSE FALSE
MSTRG.26178.10 ENSG00000183696 No_inf pgKDN_inf UPP1 protein_coding   85.63833 26.25575 94.07924 1.994766 3.252306 1.840847 4.858874 2.287477 7.231348 1.3555994 0.440173 1.6562076 0.07064167 0.097850 0.076725 -0.021125 0.83565851 0.01667749 FALSE TRUE
MSTRG.26178.6 ENSG00000183696 No_inf pgKDN_inf UPP1 protein_coding   85.63833 26.25575 94.07924 1.994766 3.252306 1.840847 12.902211 4.822205 11.355674 1.7280215 1.261798 1.2339296 0.15992500 0.191675 0.122275 -0.069400 0.95786407 0.01667749 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000183696 E001 0.0000000       7 48088628 48088643 16 +      
ENSG00000183696 E002 0.0000000       7 48088644 48088660 17 +      
ENSG00000183696 E003 0.6182469 0.0144118944 1.198012e-01 3.658096e-01 7 48088661 48088726 66 + 0.113 0.345 2.038
ENSG00000183696 E004 1.2369669 0.0123308178 2.887377e-02 1.592308e-01 7 48088727 48088871 145 + 0.202 0.535 2.038
ENSG00000183696 E005 0.2356421 0.0156855586 1.000000e+00   7 48088872 48088908 37 + 0.113 0.000 -11.273
ENSG00000183696 E006 0.1170040 0.0117473758 1.000000e+00   7 48088909 48088923 15 + 0.060 0.000 -10.328
ENSG00000183696 E007 0.3550369 0.0321874023 5.090968e-01   7 48089212 48089226 15 + 0.160 0.000 -11.744
ENSG00000183696 E008 0.2363338 0.0157251471 1.000000e+00   7 48089227 48089235 9 + 0.113 0.000 -11.273
ENSG00000183696 E009 2.2910252 0.0559520070 9.907792e-01 1.000000e+00 7 48089236 48089253 18 + 0.487 0.481 -0.033
ENSG00000183696 E010 2.7711519 0.0070339025 9.574870e-01 9.898200e-01 7 48089254 48089264 11 + 0.546 0.535 -0.050
ENSG00000183696 E011 2.7711519 0.0070339025 9.574870e-01 9.898200e-01 7 48089265 48089271 7 + 0.546 0.535 -0.050
ENSG00000183696 E012 5.4135944 0.0054030855 7.484245e-01 9.006886e-01 7 48089272 48089281 10 + 0.780 0.737 -0.175
ENSG00000183696 E013 16.2961264 0.0125382077 7.391322e-02 2.769897e-01 7 48089282 48089343 62 + 1.237 1.062 -0.628
ENSG00000183696 E014 19.2684337 0.0007902457 1.019377e-02 8.129390e-02 7 48089344 48089375 32 + 1.312 1.105 -0.733
ENSG00000183696 E015 18.6747373 0.0007183600 3.090079e-02 1.655310e-01 7 48089376 48089418 43 + 1.293 1.119 -0.617
ENSG00000183696 E016 0.0000000       7 48089509 48089611 103 +      
ENSG00000183696 E017 0.2374063 0.2828481129 1.000000e+00   7 48089612 48089636 25 + 0.113 0.000 -10.470
ENSG00000183696 E018 21.9666225 0.0006564563 4.290626e-04 7.734988e-03 7 48090188 48090249 62 + 1.379 1.105 -0.965
ENSG00000183696 E019 40.5622237 0.0040165170 9.485487e-04 1.440288e-02 7 48090250 48090364 115 + 1.623 1.417 -0.707
ENSG00000183696 E020 40.9497909 0.0047037829 3.008128e-03 3.455600e-02 7 48094763 48094827 65 + 1.623 1.437 -0.639
ENSG00000183696 E021 47.3316722 0.0003091215 4.118484e-03 4.335864e-02 7 48099670 48099787 118 + 1.676 1.529 -0.502
ENSG00000183696 E022 26.7402410 0.0035471056 1.750363e-01 4.488807e-01 7 48101824 48101870 47 + 1.425 1.327 -0.338
ENSG00000183696 E023 40.8753074 0.0006012518 2.544344e-02 1.470023e-01 7 48101871 48101982 112 + 1.609 1.485 -0.423
ENSG00000183696 E024 44.0123943 0.0003717694 5.156962e-01 7.716132e-01 7 48103297 48103411 115 + 1.618 1.583 -0.121
ENSG00000183696 E025 3.0077724 0.0118338376 8.761809e-01 9.579749e-01 7 48103412 48103561 150 + 0.564 0.584 0.091
ENSG00000183696 E026 4.1276077 0.0035924951 1.439279e-01 4.039868e-01 7 48103562 48103781 220 + 0.613 0.797 0.761
ENSG00000183696 E027 50.7397592 0.0002931664 1.883646e-07 1.034548e-05 7 48103782 48104645 864 + 1.595 1.816 0.749
ENSG00000183696 E028 37.7115970 0.0026909757 2.211817e-04 4.542732e-03 7 48104646 48105202 557 + 1.479 1.674 0.664
ENSG00000183696 E029 35.6281687 0.0006104361 5.863168e-02 2.425962e-01 7 48105203 48105669 467 + 1.490 1.587 0.334
ENSG00000183696 E030 98.0307197 0.0001771232 1.759411e-15 3.101048e-13 7 48105670 48106872 1203 + 1.870 2.106 0.795
ENSG00000183696 E031 129.6180843 0.0001623068 2.394367e-01 5.285167e-01 7 48106873 48107082 210 + 2.081 2.044 -0.121
ENSG00000183696 E032 86.2121604 0.0058318059 4.182156e-01 6.978541e-01 7 48107361 48107507 147 + 1.906 1.866 -0.135
ENSG00000183696 E033 44.1344577 0.0003441709 6.613026e-01 8.586936e-01 7 48108218 48108736 519 + 1.617 1.592 -0.085

Help

Please Click HERE to learn more details about the results from DEXseq.