ENSG00000183726

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000374358 ENSG00000183726 No_inf pgKDN_inf TMEM50A protein_coding protein_coding 97.33848 82.93372 115.5557 2.844696 2.59137 0.4785086 72.762003 70.833882 80.45834 1.193676 2.225981 0.1837779 0.7574583 0.85765 0.69810 -0.15955 0.03135729 0.03135729 FALSE TRUE
ENST00000468704 ENSG00000183726 No_inf pgKDN_inf TMEM50A protein_coding protein_coding_CDS_not_defined 97.33848 82.93372 115.5557 2.844696 2.59137 0.4785086 13.634336 3.374101 22.32359 1.334624 2.864009 2.7223706 0.1308833 0.03930 0.19200 0.15270 0.04073935 0.03135729   FALSE
ENST00000498135 ENSG00000183726 No_inf pgKDN_inf TMEM50A protein_coding protein_coding_CDS_not_defined 97.33848 82.93372 115.5557 2.844696 2.59137 0.4785086 9.602128 7.660240 10.78076 2.135760 1.554291 0.4924534 0.0982500 0.09070 0.09255 0.00185 0.97131974 0.03135729   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000183726 E001 0.8532285 0.0121944923 8.494541e-01 9.464579e-01 1 25338317 25338319 3 + 0.280 0.254 -0.185
ENSG00000183726 E002 1.9436424 0.0071138936 4.750934e-01 7.417266e-01 1 25338320 25338322 3 + 0.513 0.413 -0.507
ENSG00000183726 E003 6.3461769 0.0023140022 7.492863e-01 9.011778e-01 1 25338323 25338333 11 + 0.878 0.851 -0.104
ENSG00000183726 E004 71.0966242 0.0002765813 2.151171e-02 1.328386e-01 1 25338334 25338456 123 + 1.891 1.817 -0.248
ENSG00000183726 E005 0.6162654 0.0146923623 5.478165e-01 7.931907e-01 1 25338460 25338817 358 + 0.162 0.254 0.815
ENSG00000183726 E006 130.4457131 0.0001805320 4.749407e-04 8.384762e-03 1 25340474 25340579 106 + 2.156 2.073 -0.275
ENSG00000183726 E007 0.6168957 0.2884813557 7.108389e-01 8.831060e-01 1 25342592 25342960 369 + 0.162 0.254 0.813
ENSG00000183726 E008 156.8994915 0.0008532989 6.863170e-03 6.226378e-02 1 25342961 25343073 113 + 2.226 2.165 -0.203
ENSG00000183726 E009 121.4437289 0.0001432121 1.519299e-01 4.156088e-01 1 25351626 25351693 68 + 2.102 2.072 -0.101
ENSG00000183726 E010 155.0519097 0.0001155575 5.119872e-02 2.240768e-01 1 25352882 25352974 93 + 2.210 2.173 -0.125
ENSG00000183726 E011 129.2575007 0.0002411615 8.228974e-02 2.953837e-01 1 25356793 25356853 61 + 2.132 2.094 -0.125
ENSG00000183726 E012 527.7630987 0.0005858483 2.421919e-13 3.401661e-11 1 25360660 25362361 1702 + 2.675 2.770 0.317

Help

Please Click HERE to learn more details about the results from DEXseq.