ENSG00000183826

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000314100 ENSG00000183826 No_inf pgKDN_inf BTBD9 protein_coding protein_coding 3.11372 2.123554 4.13562 0.102276 0.1116508 0.9583293 0.9232631 0.19544083 0.5293204 0.19544083 0.5293204 1.3924196 0.3072167 0.100550 0.1237 0.023150 0.979265057 0.002828067 FALSE TRUE
ENST00000481247 ENSG00000183826 No_inf pgKDN_inf BTBD9 protein_coding protein_coding 3.11372 2.123554 4.13562 0.102276 0.1116508 0.9583293 1.1067219 1.85545485 1.3600812 0.23661299 0.5043673 -0.4452661 0.4127250 0.868775 0.3307 -0.538075 0.132094265 0.002828067 FALSE TRUE
ENST00000649492 ENSG00000183826 No_inf pgKDN_inf BTBD9 protein_coding protein_coding 3.11372 2.123554 4.13562 0.102276 0.1116508 0.9583293 1.0598170 0.07265843 2.2462187 0.07265843 0.1724311 4.7706012 0.2731000 0.030675 0.5456 0.514925 0.002828067 0.002828067 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000183826 E001 30.8690941 0.0006034086 1.269905e-06 5.731467e-05 6 38168451 38171892 3442 - 1.385 1.613 0.783
ENSG00000183826 E002 61.9697140 0.0004673208 8.759757e-02 3.067152e-01 6 38171893 38174958 3066 - 1.816 1.768 -0.160
ENSG00000183826 E003 4.5632025 0.0041272780 6.531232e-03 6.000945e-02 6 38174959 38175182 224 - 0.859 0.519 -1.435
ENSG00000183826 E004 1.2248807 0.0099223625 6.106662e-01 8.306795e-01 6 38192519 38192597 79 - 0.309 0.388 0.472
ENSG00000183826 E005 2.5803663 0.0311361879 3.593897e-01 6.487855e-01 6 38256409 38256516 108 - 0.488 0.620 0.609
ENSG00000183826 E006 3.1863328 0.0044933500 4.077046e-01 6.901585e-01 6 38288272 38288461 190 - 0.568 0.676 0.472
ENSG00000183826 E007 1.8151268 0.0162642447 5.029542e-01 7.625744e-01 6 38344984 38345093 110 - 0.488 0.388 -0.528
ENSG00000183826 E008 0.0000000       6 38402817 38402903 87 -      
ENSG00000183826 E009 0.0000000       6 38504494 38504562 69 -      
ENSG00000183826 E010 0.0000000       6 38571710 38571794 85 -      
ENSG00000183826 E011 0.0000000       6 38577599 38577599 1 -      
ENSG00000183826 E012 1.8485447 0.0152000562 1.697920e-01 4.418543e-01 6 38577600 38577719 120 - 0.352 0.556 1.057
ENSG00000183826 E013 3.7531281 0.0110923359 4.706341e-01 7.382695e-01 6 38580218 38580437 220 - 0.712 0.620 -0.391
ENSG00000183826 E014 5.9022306 0.0026255538 2.367289e-02 1.407223e-01 6 38592576 38592840 265 - 0.929 0.676 -0.998
ENSG00000183826 E015 3.8522171 0.0051289945 1.057066e-01 3.402269e-01 6 38593964 38594235 272 - 0.762 0.556 -0.882
ENSG00000183826 E016 1.7884653 0.0078629453 1.633190e-02 1.110775e-01 6 38594236 38594327 92 - 0.568 0.198 -2.229
ENSG00000183826 E017 0.0000000       6 38594328 38594375 48 -      
ENSG00000183826 E018 0.1268540 0.0125353344 3.854127e-01   6 38595770 38596067 298 - 0.000 0.110 9.640
ENSG00000183826 E019 2.7958672 0.0055077325 7.844259e-01 9.168385e-01 6 38597910 38598057 148 - 0.592 0.556 -0.166
ENSG00000183826 E020 1.8238392 0.0077006507 8.795084e-01 9.593376e-01 6 38598058 38598121 64 - 0.458 0.436 -0.113
ENSG00000183826 E021 0.1265070 0.0123323651 3.856708e-01   6 38612834 38613033 200 - 0.000 0.110 9.641
ENSG00000183826 E022 0.9728131 0.0133222322 8.017068e-01 9.259932e-01 6 38639800 38640148 349 - 0.309 0.271 -0.265

Help

Please Click HERE to learn more details about the results from DEXseq.