ENSG00000183955

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000402868 ENSG00000183955 No_inf pgKDN_inf KMT5A protein_coding protein_coding 31.73874 43.68775 26.90452 2.325675 2.81288 -0.6991741 8.366122 9.1642439 9.1334158 3.1536740 3.5608923 -0.004856032 0.27688333 0.216975 0.352725 0.135750 0.870238144 0.003038101 FALSE TRUE
ENST00000437519 ENSG00000183955 No_inf pgKDN_inf KMT5A protein_coding nonsense_mediated_decay 31.73874 43.68775 26.90452 2.325675 2.81288 -0.6991741 7.772140 14.7295874 2.3298667 5.7193180 2.3298667 -2.655197893 0.22748333 0.330575 0.076900 -0.253675 0.401536324 0.003038101 FALSE TRUE
ENST00000461103 ENSG00000183955 No_inf pgKDN_inf KMT5A protein_coding retained_intron 31.73874 43.68775 26.90452 2.325675 2.81288 -0.6991741 3.329671 4.5173390 0.8397655 0.8848144 0.8397655 -2.413526642 0.11225833 0.101500 0.041175 -0.060325 0.198302984 0.003038101 FALSE FALSE
ENST00000485469 ENSG00000183955 No_inf pgKDN_inf KMT5A protein_coding protein_coding_CDS_not_defined 31.73874 43.68775 26.90452 2.325675 2.81288 -0.6991741 2.860049 0.0000000 6.2763890 0.0000000 2.5135794 9.296087729 0.09620000 0.000000 0.212225 0.212225 0.003038101 0.003038101 FALSE FALSE
ENST00000537270 ENSG00000183955 No_inf pgKDN_inf KMT5A protein_coding protein_coding_CDS_not_defined 31.73874 43.68775 26.90452 2.325675 2.81288 -0.6991741 2.610611 5.9807280 0.9730595 1.4960281 0.9730595 -2.607380686 0.06685833 0.134200 0.032125 -0.102075 0.115460547 0.003038101   FALSE
MSTRG.7388.11 ENSG00000183955 No_inf pgKDN_inf KMT5A protein_coding   31.73874 43.68775 26.90452 2.325675 2.81288 -0.6991741 2.029653 4.0481481 2.0408097 4.0481481 1.4654010 -0.984627880 0.05837500 0.096075 0.079050 -0.017025 0.787902359 0.003038101 FALSE TRUE
MSTRG.7388.4 ENSG00000183955 No_inf pgKDN_inf KMT5A protein_coding   31.73874 43.68775 26.90452 2.325675 2.81288 -0.6991741 1.941259 1.6212960 2.3436314 0.6597532 1.1104335 0.528869827 0.06620000 0.039600 0.083275 0.043675 0.761102132 0.003038101 FALSE TRUE
MSTRG.7388.6 ENSG00000183955 No_inf pgKDN_inf KMT5A protein_coding   31.73874 43.68775 26.90452 2.325675 2.81288 -0.6991741 1.812241 0.7882144 2.9675833 0.7882144 1.1653045 1.899293642 0.07172500 0.018700 0.122525 0.103825 0.296241784 0.003038101 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000183955 E001 0.4811617 0.0186864626 0.12281646   12 123384132 123384165 34 + 0.292 0.074 -2.360
ENSG00000183955 E002 0.8446928 0.2391572348 0.12533715 0.37532251 12 123384166 123384172 7 + 0.415 0.138 -2.097
ENSG00000183955 E003 1.4427325 0.1238670975 0.02377676 0.14113755 12 123384173 123384208 36 + 0.589 0.194 -2.359
ENSG00000183955 E004 2.8949687 0.0049192506 0.01217348 0.09136717 12 123388442 123388757 316 + 0.292 0.676 1.962
ENSG00000183955 E005 0.1186381 0.0119202393 0.29823659   12 123388900 123388924 25 + 0.121 0.000 -11.963
ENSG00000183955 E006 0.4913316 0.0162358178 0.58172677   12 123388925 123388968 44 + 0.215 0.138 -0.775
ENSG00000183955 E007 4.9094485 0.0377597045 0.21986267 0.50649552 12 123388969 123389182 214 + 0.850 0.693 -0.631
ENSG00000183955 E008 1.6415415 0.0122622729 0.01730629 0.11516316 12 123389271 123389432 162 + 0.121 0.511 2.810
ENSG00000183955 E009 4.5221161 0.0091368122 0.07302239 0.27456705 12 123389433 123389482 50 + 0.850 0.640 -0.853
ENSG00000183955 E010 2.9537178 0.0082463280 0.60352452 0.82699604 12 123389483 123389554 72 + 0.623 0.559 -0.289
ENSG00000183955 E011 0.4990396 0.5109753815 0.92326978   12 123390042 123390150 109 + 0.121 0.194 0.811
ENSG00000183955 E012 0.8714471 0.0287576056 0.66530887 0.86080449 12 123390297 123390342 46 + 0.215 0.287 0.547
ENSG00000183955 E013 9.9319535 0.0237403950 0.11163319 0.35096615 12 123390630 123390710 81 + 1.119 0.957 -0.596
ENSG00000183955 E014 9.0782890 0.0476755629 0.23703646 0.52605203 12 123390711 123390786 76 + 1.075 0.929 -0.539
ENSG00000183955 E015 0.6352429 0.0155225269 0.08261274 0.29609486 12 123390787 123391304 518 + 0.000 0.287 12.158
ENSG00000183955 E016 0.2537694 0.0160051454 0.50299032   12 123391380 123391430 51 + 0.000 0.138 10.951
ENSG00000183955 E017 28.3514702 0.0006746286 0.11549606 0.35828604 12 123395047 123395266 220 + 1.497 1.419 -0.268
ENSG00000183955 E018 18.8285333 0.0007982626 0.67855032 0.86702044 12 123396345 123396432 88 + 1.255 1.291 0.127
ENSG00000183955 E019 11.2722321 0.0019047457 0.63545325 0.84444231 12 123403573 123403632 60 + 1.038 1.087 0.178
ENSG00000183955 E020 18.2077766 0.0142169170 0.61719017 0.83423223 12 123404884 123405074 191 + 1.231 1.282 0.181
ENSG00000183955 E021 160.0345487 0.0043117659 0.06146824 0.24904055 12 123407493 123409731 2239 + 2.156 2.203 0.158

Help

Please Click HERE to learn more details about the results from DEXseq.