ENSG00000184060

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000330889 ENSG00000184060 No_inf pgKDN_inf ADAP2 protein_coding protein_coding 20.16141 20.40312 24.45953 2.594307 3.053085 0.2614898 5.9286563 3.768570 7.7148458 1.2690424 1.5220421 1.0316658 0.32442500 0.186500 0.346900 0.160400 7.468432e-01 5.321149e-16 FALSE TRUE
ENST00000470962 ENSG00000184060 No_inf pgKDN_inf ADAP2 protein_coding retained_intron 20.16141 20.40312 24.45953 2.594307 3.053085 0.2614898 3.0896984 0.000000 7.3349526 0.0000000 1.0461282 9.5206094 0.14450000 0.000000 0.313900 0.313900 1.443979e-09 5.321149e-16   FALSE
ENST00000480980 ENSG00000184060 No_inf pgKDN_inf ADAP2 protein_coding retained_intron 20.16141 20.40312 24.45953 2.594307 3.053085 0.2614898 1.5453497 2.527417 0.5209989 0.4179737 0.3390915 -2.2565798 0.09237500 0.126950 0.024925 -0.102025 1.776710e-01 5.321149e-16   FALSE
ENST00000583688 ENSG00000184060 No_inf pgKDN_inf ADAP2 protein_coding protein_coding_CDS_not_defined 20.16141 20.40312 24.45953 2.594307 3.053085 0.2614898 1.1068870 1.157893 1.3146382 0.4960803 0.8345557 0.1816903 0.05765833 0.052475 0.061425 0.008950 1.000000e+00 5.321149e-16   FALSE
ENST00000584989 ENSG00000184060 No_inf pgKDN_inf ADAP2 protein_coding protein_coding 20.16141 20.40312 24.45953 2.594307 3.053085 0.2614898 2.5072522 1.070985 3.7233684 1.0709851 3.7233684 1.7881312 0.08765000 0.038450 0.111275 0.072825 1.000000e+00 5.321149e-16 FALSE FALSE
MSTRG.12399.11 ENSG00000184060 No_inf pgKDN_inf ADAP2 protein_coding   20.16141 20.40312 24.45953 2.594307 3.053085 0.2614898 2.9437115 8.831134 0.0000000 0.6588361 0.0000000 -9.7880877 0.14770833 0.443125 0.000000 -0.443125 5.321149e-16 5.321149e-16 FALSE FALSE
MSTRG.12399.8 ENSG00000184060 No_inf pgKDN_inf ADAP2 protein_coding   20.16141 20.40312 24.45953 2.594307 3.053085 0.2614898 0.8789329 1.658881 0.0000000 1.6588807 0.0000000 -7.3827370 0.04729167 0.089300 0.000000 -0.089300 8.450051e-01 5.321149e-16 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000184060 E001 2.5888882 0.196716433 0.427801988 0.70633296 17 30906344 30906644 301 + 0.493 0.609 0.540
ENSG00000184060 E002 0.1176306 0.011811522 0.588196395   17 30921680 30921703 24 + 0.091 0.000 -11.263
ENSG00000184060 E003 0.7246754 0.014128622 0.479649629 0.74532355 17 30921704 30921916 213 + 0.287 0.179 -0.873
ENSG00000184060 E004 0.3522653 0.029496505 0.123687127   17 30921917 30921931 15 + 0.231 0.000 -12.661
ENSG00000184060 E005 0.3522653 0.029496505 0.123687127   17 30921932 30921934 3 + 0.231 0.000 -12.661
ENSG00000184060 E006 0.4791192 0.025330180 0.366182281   17 30921935 30921944 10 + 0.231 0.099 -1.458
ENSG00000184060 E007 0.3621152 0.188637010 0.669864699   17 30921945 30921947 3 + 0.167 0.099 -0.873
ENSG00000184060 E008 0.4808184 0.026891339 0.365337849   17 30921948 30921970 23 + 0.231 0.099 -1.458
ENSG00000184060 E009 4.1005486 0.003518100 0.029931815 0.16271974 17 30921971 30922108 138 + 0.821 0.551 -1.136
ENSG00000184060 E010 6.9287455 0.002375029 0.262793239 0.55558350 17 30922940 30923070 131 + 0.953 0.838 -0.437
ENSG00000184060 E011 0.2541163 0.015951482 0.213416744   17 30926809 30926826 18 + 0.000 0.179 11.461
ENSG00000184060 E012 5.0091096 0.038075353 0.855105372 0.94898081 17 30926827 30926918 92 + 0.772 0.786 0.057
ENSG00000184060 E013 7.2015118 0.002100312 0.761288733 0.90681135 17 30931889 30931968 80 + 0.929 0.898 -0.118
ENSG00000184060 E014 8.2999444 0.014041397 0.577170119 0.81101251 17 30934185 30934297 113 + 0.996 0.938 -0.214
ENSG00000184060 E015 6.5717350 0.003000098 0.448371539 0.72241534 17 30944907 30945027 121 + 0.917 0.838 -0.304
ENSG00000184060 E016 2.9580555 0.030425435 0.332875073 0.62496203 17 30945028 30945041 14 + 0.524 0.661 0.612
ENSG00000184060 E017 2.8309192 0.029893463 0.431632298 0.70932601 17 30945042 30945053 12 + 0.524 0.636 0.505
ENSG00000184060 E018 6.6812247 0.002163348 0.246688011 0.53730586 17 30949287 30949370 84 + 0.941 0.821 -0.458
ENSG00000184060 E019 6.5793943 0.002277583 0.625197875 0.83866642 17 30953288 30953350 63 + 0.905 0.854 -0.195
ENSG00000184060 E020 0.4901058 0.016179127 0.927292292   17 30954203 30954239 37 + 0.167 0.179 0.127
ENSG00000184060 E021 0.7156806 0.062005662 0.132001947 0.38549886 17 30954240 30954253 14 + 0.337 0.099 -2.195
ENSG00000184060 E022 0.8421876 0.014846522 0.307446581 0.60061663 17 30954254 30954261 8 + 0.337 0.179 -1.195
ENSG00000184060 E023 2.7679211 0.005213382 0.034464049 0.17731413 17 30954262 30954477 216 + 0.697 0.404 -1.376
ENSG00000184060 E024 4.9035924 0.004543976 0.554664795 0.79742213 17 30954478 30954480 3 + 0.736 0.804 0.271
ENSG00000184060 E025 7.8146930 0.009212154 0.884588555 0.96112732 17 30954481 30954555 75 + 0.952 0.938 -0.054
ENSG00000184060 E026 2.6659555 0.005788301 0.284950686 0.57866446 17 30956241 30956391 151 + 0.631 0.484 -0.681
ENSG00000184060 E027 0.0000000       17 30956392 30956469 78 +      
ENSG00000184060 E028 0.2539903 0.016008516 0.213233021   17 30956470 30956728 259 + 0.000 0.179 11.461
ENSG00000184060 E029 129.1251465 0.000189316 0.003877628 0.04153644 17 30957835 30959484 1650 + 2.090 2.138 0.160

Help

Please Click HERE to learn more details about the results from DEXseq.