ENSG00000184216

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369980 ENSG00000184216 No_inf pgKDN_inf IRAK1 protein_coding protein_coding 78.45003 58.3343 91.15519 7.617261 8.229227 0.6438914 41.785848 29.020382 46.7647248 4.3065355 4.0746750 0.6881656 0.55509167 0.536000 0.539900 0.003900 1.00000000 0.03232989 FALSE  
ENST00000467236 ENSG00000184216 No_inf pgKDN_inf IRAK1 protein_coding retained_intron 78.45003 58.3343 91.15519 7.617261 8.229227 0.6438914 9.813072 6.211680 13.5467829 3.7573000 4.9934592 1.1236387 0.11579167 0.094275 0.140550 0.046275 0.73614109 0.03232989 FALSE  
ENST00000477274 ENSG00000184216 No_inf pgKDN_inf IRAK1 protein_coding protein_coding_CDS_not_defined 78.45003 58.3343 91.15519 7.617261 8.229227 0.6438914 13.917152 8.268837 19.6047503 6.3688510 6.1648054 1.2444390 0.15485833 0.111575 0.200775 0.089200 0.51456730 0.03232989 FALSE  
MSTRG.30564.2 ENSG00000184216 No_inf pgKDN_inf IRAK1 protein_coding   78.45003 58.3343 91.15519 7.617261 8.229227 0.6438914 2.193306 3.561435 0.4918819 0.5501839 0.4918819 -2.8310838 0.03216667 0.062150 0.007200 -0.054950 0.03232989 0.03232989 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000184216 E001 0.6103171 0.2078332316 8.738028e-01 9.569172e-01 X 154010338 154010457 120 - 0.216 0.192 -0.213
ENSG00000184216 E002 0.1271363 0.0123375628 4.141932e-01   X 154010458 154010505 48 - 0.000 0.107 9.674
ENSG00000184216 E003 0.1271363 0.0123375628 4.141932e-01   X 154010506 154010506 1 - 0.000 0.107 9.674
ENSG00000184216 E004 2.9753297 0.0225548136 3.257350e-02 1.710355e-01 X 154010507 154010519 13 - 0.435 0.737 1.373
ENSG00000184216 E005 3.0929603 0.0538202337 7.468757e-02 2.786524e-01 X 154010520 154010526 7 - 0.468 0.737 1.203
ENSG00000184216 E006 7.6654263 0.0060677735 3.410282e-03 3.804140e-02 X 154010527 154010545 19 - 0.774 1.074 1.134
ENSG00000184216 E007 52.0037358 0.0003009986 3.112481e-01 6.044525e-01 X 154010546 154010721 176 - 1.703 1.745 0.142
ENSG00000184216 E008 57.9297361 0.0002975467 7.104213e-01 8.829636e-01 X 154010722 154010811 90 - 1.762 1.776 0.049
ENSG00000184216 E009 162.4418316 0.0001473234 1.369593e-01 3.939606e-01 X 154010812 154011116 305 - 2.196 2.230 0.114
ENSG00000184216 E010 164.9285050 0.0026396637 2.049878e-01 4.881382e-01 X 154011117 154011562 446 - 2.201 2.238 0.126
ENSG00000184216 E011 57.1976610 0.0004415719 9.474804e-02 3.202244e-01 X 154011563 154011687 125 - 1.732 1.798 0.224
ENSG00000184216 E012 26.5823335 0.0010150714 7.871011e-01 9.182477e-01 X 154011688 154011730 43 - 1.432 1.447 0.054
ENSG00000184216 E013 44.2925754 0.0003716244 6.117080e-01 8.310655e-01 X 154011731 154011826 96 - 1.644 1.666 0.077
ENSG00000184216 E014 33.3188424 0.0004570722 6.246558e-01 8.385644e-01 X 154011827 154011858 32 - 1.522 1.547 0.086
ENSG00000184216 E015 39.2196176 0.0034841019 7.310885e-01 8.932179e-01 X 154011859 154011917 59 - 1.611 1.593 -0.061
ENSG00000184216 E016 12.9246075 0.0010626848 5.612508e-08 3.471388e-06 X 154011918 154012528 611 - 0.885 1.329 1.608
ENSG00000184216 E017 64.5707886 0.0064011656 9.692474e-01 9.936412e-01 X 154012529 154012678 150 - 1.816 1.813 -0.010
ENSG00000184216 E018 2.2330394 0.2547621626 1.831797e-01 4.598973e-01 X 154012679 154013042 364 - 0.360 0.638 1.371
ENSG00000184216 E019 86.2332111 0.0001887087 1.239093e-01 3.728480e-01 X 154013043 154013343 301 - 1.961 1.911 -0.167
ENSG00000184216 E020 37.2270461 0.0004356460 1.622739e-02 1.107018e-01 X 154013344 154013433 90 - 1.631 1.511 -0.407
ENSG00000184216 E021 72.9065715 0.0002256531 3.575507e-01 6.471623e-01 X 154014042 154014278 237 - 1.881 1.849 -0.109
ENSG00000184216 E022 1.8685545 0.0083649253 2.140748e-02 1.324680e-01 X 154014279 154014360 82 - 0.270 0.609 1.832
ENSG00000184216 E023 23.9653048 0.0005816253 1.711272e-01 4.434652e-01 X 154016032 154016038 7 - 1.357 1.439 0.284
ENSG00000184216 E024 36.9481508 0.0003813492 7.320937e-01 8.935423e-01 X 154016039 154016097 59 - 1.570 1.587 0.057
ENSG00000184216 E025 75.1713371 0.0020723520 7.222038e-01 8.883174e-01 X 154016437 154016644 208 - 1.886 1.872 -0.047
ENSG00000184216 E026 62.8147178 0.0030430015 4.426168e-01 7.179181e-01 X 154016949 154017067 119 - 1.818 1.784 -0.113
ENSG00000184216 E027 65.0242604 0.0002771883 4.981258e-01 7.586885e-01 X 154018006 154018120 115 - 1.829 1.804 -0.085
ENSG00000184216 E028 47.3853005 0.0003523007 6.525514e-02 2.571838e-01 X 154018291 154018345 55 - 1.718 1.637 -0.274
ENSG00000184216 E029 33.9511697 0.0015866734 3.756280e-01 6.630812e-01 X 154018346 154018355 10 - 1.562 1.515 -0.161
ENSG00000184216 E030 59.6144319 0.0052079145 3.461057e-01 6.369878e-01 X 154018599 154018787 189 - 1.801 1.756 -0.151
ENSG00000184216 E031 0.2457744 0.0164848518 8.413420e-01   X 154018788 154018945 158 - 0.085 0.107 0.372
ENSG00000184216 E032 27.9285350 0.0005148260 8.737905e-01 9.569172e-01 X 154018975 154019078 104 - 1.455 1.464 0.031
ENSG00000184216 E033 44.3870161 0.0070703955 2.368547e-01 5.257871e-01 X 154019197 154019328 132 - 1.684 1.617 -0.229
ENSG00000184216 E034 51.3784094 0.0041469642 2.389152e-03 2.913329e-02 X 154019431 154019598 168 - 1.779 1.628 -0.512
ENSG00000184216 E035 2.5400219 0.0065502582 3.455178e-01 6.365072e-01 X 154019599 154019676 78 - 0.603 0.470 -0.628
ENSG00000184216 E036 30.3192011 0.0005632274 6.548799e-01 8.552129e-01 X 154019677 154019910 234 - 1.505 1.481 -0.083

Help

Please Click HERE to learn more details about the results from DEXseq.