ENSG00000184381

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000402064 ENSG00000184381 No_inf pgKDN_inf PLA2G6 protein_coding protein_coding 8.884068 17.48278 4.390919 2.744827 1.623823 -1.990883 0.35373539 0.7172344 0.0000000 0.7172344 0.0000000 -6.18434852 0.05946667 0.047075 0.000000 -0.047075 1.00000000 0.01636583 FALSE TRUE
ENST00000452972 ENSG00000184381 No_inf pgKDN_inf PLA2G6 protein_coding protein_coding_CDS_not_defined 8.884068 17.48278 4.390919 2.744827 1.623823 -1.990883 0.34169299 0.5090725 0.5160064 0.3259857 0.3049239 0.01914437 0.05338333 0.026925 0.133225 0.106300 0.75436119 0.01636583   FALSE
ENST00000480154 ENSG00000184381 No_inf pgKDN_inf PLA2G6 protein_coding retained_intron 8.884068 17.48278 4.390919 2.744827 1.623823 -1.990883 0.91125017 2.7337505 0.0000000 1.2956528 0.0000000 -8.10000549 0.04730833 0.141925 0.000000 -0.141925 0.27611522 0.01636583 FALSE FALSE
ENST00000491986 ENSG00000184381 No_inf pgKDN_inf PLA2G6 protein_coding retained_intron 8.884068 17.48278 4.390919 2.744827 1.623823 -1.990883 1.10139545 3.2155627 0.0000000 0.6419703 0.0000000 -8.33340704 0.07623333 0.194875 0.000000 -0.194875 0.01636583 0.01636583   FALSE
ENST00000496409 ENSG00000184381 No_inf pgKDN_inf PLA2G6 protein_coding retained_intron 8.884068 17.48278 4.390919 2.744827 1.623823 -1.990883 0.67965907 1.5097098 0.2656887 0.5912286 0.1594339 -2.46268394 0.08022500 0.092250 0.093950 0.001700 0.99836304 0.01636583 TRUE TRUE
ENST00000655142 ENSG00000184381 No_inf pgKDN_inf PLA2G6 protein_coding nonsense_mediated_decay 8.884068 17.48278 4.390919 2.744827 1.623823 -1.990883 0.68068413 0.6222783 0.8945052 0.6222783 0.3083866 0.51656890 0.13877500 0.037025 0.250675 0.213650 0.23688838 0.01636583 FALSE TRUE
ENST00000660610 ENSG00000184381 No_inf pgKDN_inf PLA2G6 protein_coding protein_coding 8.884068 17.48278 4.390919 2.744827 1.623823 -1.990883 0.04970008 0.0000000 0.1491002 0.0000000 0.1491002 3.99186410 0.02072500 0.000000 0.062175 0.062175 0.56854112 0.01636583 FALSE TRUE
ENST00000663895 ENSG00000184381 No_inf pgKDN_inf PLA2G6 protein_coding protein_coding 8.884068 17.48278 4.390919 2.744827 1.623823 -1.990883 0.83183076 1.4141156 0.5448067 0.8740719 0.5448067 -1.36000906 0.10519167 0.076450 0.169625 0.093175 0.99423492 0.01636583 FALSE TRUE
MSTRG.19392.42 ENSG00000184381 No_inf pgKDN_inf PLA2G6 protein_coding   8.884068 17.48278 4.390919 2.744827 1.623823 -1.990883 1.33845552 1.7121314 1.2812625 1.7121314 1.2812625 -0.41541286 0.11292500 0.067700 0.138725 0.071025 0.83600925 0.01636583   FALSE
MSTRG.19392.6 ENSG00000184381 No_inf pgKDN_inf PLA2G6 protein_coding   8.884068 17.48278 4.390919 2.744827 1.623823 -1.990883 1.08557143 2.9447549 0.0000000 0.5981344 0.0000000 -8.20689465 0.09887500 0.192650 0.000000 -0.192650 0.03352450 0.01636583 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000184381 E001 0.0000000       22 38111495 38111495 1 -      
ENSG00000184381 E002 0.1187032 0.011907776 0.06188377   22 38111496 38111499 4 - 0.189 0.000 -11.848
ENSG00000184381 E003 0.1187032 0.011907776 0.06188377   22 38111500 38111539 40 - 0.189 0.000 -14.938
ENSG00000184381 E004 0.1187032 0.011907776 0.06188377   22 38111540 38111569 30 - 0.189 0.000 -14.938
ENSG00000184381 E005 0.6264628 0.014399713 0.78845534 0.91890468 22 38111570 38111581 12 - 0.189 0.158 -0.306
ENSG00000184381 E006 1.1424347 0.010944000 0.21254006 0.49772344 22 38111582 38111606 25 - 0.000 0.299 13.317
ENSG00000184381 E007 5.0424122 0.002920902 0.28310385 0.57671263 22 38111607 38111753 147 - 0.502 0.696 0.864
ENSG00000184381 E008 3.8904719 0.003714487 0.95750134 0.98981997 22 38111754 38111826 73 - 0.571 0.587 0.073
ENSG00000184381 E009 1.5154714 0.009264416 0.46849013 0.73661955 22 38111827 38111830 4 - 0.189 0.345 1.154
ENSG00000184381 E010 2.7768298 0.005210164 0.35537485 0.64515086 22 38111831 38111871 41 - 0.320 0.505 1.016
ENSG00000184381 E011 1.7695263 0.007785818 0.34520921 0.63622586 22 38111872 38111872 1 - 0.189 0.386 1.395
ENSG00000184381 E012 1.8963803 0.007616870 0.29621104 0.58928930 22 38111873 38111875 3 - 0.189 0.405 1.502
ENSG00000184381 E013 2.0236427 0.007157542 0.25395340 0.54556755 22 38111876 38111882 7 - 0.189 0.423 1.601
ENSG00000184381 E014 11.0664081 0.003948456 0.56550075 0.80431312 22 38111883 38112167 285 - 0.877 0.972 0.357
ENSG00000184381 E015 8.5185259 0.066590926 0.65672389 0.85639447 22 38112168 38112305 138 - 0.907 0.848 -0.226
ENSG00000184381 E016 4.5243639 0.008712882 0.75676708 0.90425761 22 38112504 38112577 74 - 0.571 0.645 0.327
ENSG00000184381 E017 0.0000000       22 38112578 38112855 278 -      
ENSG00000184381 E018 3.2714659 0.004908921 0.53606936 0.78542732 22 38113487 38113537 51 - 0.420 0.548 0.633
ENSG00000184381 E019 5.2587535 0.002999356 0.56664172 0.80470574 22 38113538 38113654 117 - 0.729 0.676 -0.218
ENSG00000184381 E020 0.3804973 0.016242953 1.00000000   22 38114434 38114570 137 - 0.000 0.124 12.065
ENSG00000184381 E021 0.0000000       22 38114571 38114637 67 -      
ENSG00000184381 E022 3.3845636 0.004239994 0.70190487 0.87870892 22 38115527 38115547 21 - 0.571 0.534 -0.168
ENSG00000184381 E023 3.0018301 0.004999864 0.51279053 0.76976383 22 38115548 38115555 8 - 0.571 0.490 -0.380
ENSG00000184381 E024 7.1679143 0.001936976 0.70739285 0.88128349 22 38115556 38115681 126 - 0.729 0.806 0.309
ENSG00000184381 E025 1.3686020 0.055126733 0.35190140 0.64204357 22 38115682 38115849 168 - 0.420 0.274 -0.891
ENSG00000184381 E026 2.8767728 0.005390537 0.45251706 0.72567957 22 38116075 38116093 19 - 0.571 0.474 -0.458
ENSG00000184381 E027 5.1345473 0.002684234 0.51868798 0.77360231 22 38116094 38116211 118 - 0.729 0.666 -0.261
ENSG00000184381 E028 0.0000000       22 38116320 38116410 91 -      
ENSG00000184381 E029 0.9880124 0.012603989 0.13704497 0.39410043 22 38119017 38119805 789 - 0.420 0.190 -1.569
ENSG00000184381 E030 7.0026788 0.021856071 0.27177682 0.56555333 22 38120759 38120909 151 - 0.877 0.767 -0.431
ENSG00000184381 E031 0.8805177 0.123146882 1.00000000 1.00000000 22 38120910 38121040 131 - 0.189 0.220 0.279
ENSG00000184381 E032 6.1240494 0.002789443 0.21327175 0.49848749 22 38123095 38123203 109 - 0.844 0.715 -0.517
ENSG00000184381 E033 3.5190682 0.004169691 0.82581182 0.93692067 22 38123204 38123258 55 - 0.502 0.561 0.279
ENSG00000184381 E034 1.3764735 0.035320064 0.82347649 0.93591360 22 38125639 38125691 53 - 0.320 0.299 -0.136
ENSG00000184381 E035 5.2620324 0.003979810 0.56957791 0.80645844 22 38126371 38126449 79 - 0.729 0.676 -0.218
ENSG00000184381 E036 1.6486837 0.034514523 0.09275012 0.31625125 22 38126450 38126473 24 - 0.000 0.386 13.724
ENSG00000184381 E037 1.2690366 0.010908880 0.16888206 0.44032124 22 38126474 38126525 52 - 0.000 0.322 13.436
ENSG00000184381 E038 0.1271363 0.012674605 0.73678554   22 38126526 38126527 2 - 0.000 0.045 10.722
ENSG00000184381 E039 1.6504799 0.008574163 0.08739055 0.30639809 22 38126528 38126755 228 - 0.000 0.386 13.732
ENSG00000184381 E040 3.9384957 0.016421202 0.00295008 0.03411441 22 38126762 38126995 234 - 0.000 0.645 14.733
ENSG00000184381 E041 4.0547128 0.011015847 0.02107705 0.13120610 22 38126996 38127406 411 - 0.189 0.645 2.649
ENSG00000184381 E042 0.7620323 0.013912526 0.45595493 0.72839575 22 38127407 38127458 52 - 0.000 0.220 12.861
ENSG00000184381 E043 0.7623146 0.132326617 0.51707577 0.77262680 22 38128161 38128268 108 - 0.000 0.220 12.841
ENSG00000184381 E044 4.9826789 0.003099378 0.05708402 0.23881923 22 38128269 38128430 162 - 0.844 0.622 -0.907
ENSG00000184381 E045 2.3761303 0.006191703 0.54463588 0.79105771 22 38129454 38129517 64 - 0.502 0.423 -0.399
ENSG00000184381 E046 1.5154100 0.008585371 0.46838996 0.73654861 22 38129518 38129540 23 - 0.189 0.345 1.154
ENSG00000184381 E047 0.2543986 0.016326540 1.00000000   22 38129541 38129562 22 - 0.000 0.086 11.582
ENSG00000184381 E048 0.0000000       22 38131990 38132111 122 -      
ENSG00000184381 E049 0.0000000       22 38132831 38133013 183 -      
ENSG00000184381 E050 0.0000000       22 38134988 38135084 97 -      
ENSG00000184381 E051 0.0000000       22 38139982 38140064 83 -      
ENSG00000184381 E052 0.0000000       22 38140065 38140133 69 -      
ENSG00000184381 E053 0.0000000       22 38140134 38140169 36 -      
ENSG00000184381 E054 0.0000000       22 38143105 38143113 9 -      
ENSG00000184381 E055 0.0000000       22 38143114 38143228 115 -      
ENSG00000184381 E056 0.0000000       22 38143229 38143236 8 -      
ENSG00000184381 E057 0.0000000       22 38143237 38143288 52 -      
ENSG00000184381 E058 0.0000000       22 38143289 38143494 206 -      
ENSG00000184381 E059 0.0000000       22 38144896 38144978 83 -      
ENSG00000184381 E060 0.0000000       22 38145438 38145492 55 -      
ENSG00000184381 E061 0.0000000       22 38145493 38145562 70 -      
ENSG00000184381 E062 0.0000000       22 38145563 38145591 29 -      
ENSG00000184381 E063 0.0000000       22 38145592 38145605 14 -      
ENSG00000184381 E064 0.0000000       22 38145606 38145623 18 -      
ENSG00000184381 E065 0.0000000       22 38145624 38145653 30 -      
ENSG00000184381 E066 0.0000000       22 38147350 38147367 18 -      
ENSG00000184381 E067 0.0000000       22 38147368 38147378 11 -      
ENSG00000184381 E068 0.0000000       22 38147379 38147417 39 -      
ENSG00000184381 E069 0.0000000       22 38147418 38147475 58 -      
ENSG00000184381 E070 0.0000000       22 38148493 38148623 131 -      
ENSG00000184381 E071 0.0000000       22 38163415 38163672 258 -      
ENSG00000184381 E072 0.0000000       22 38167901 38167917 17 -      
ENSG00000184381 E073 0.0000000       22 38167918 38167942 25 -      
ENSG00000184381 E074 0.0000000       22 38167943 38167984 42 -      
ENSG00000184381 E075 0.0000000       22 38167985 38168090 106 -      
ENSG00000184381 E076 1.7677324 0.135045498 0.42712052 0.70564286 22 38169218 38169274 57 - 0.189 0.386 1.395
ENSG00000184381 E077 4.4947352 0.121629292 0.24834656 0.53924182 22 38169275 38169467 193 - 0.771 0.599 -0.721
ENSG00000184381 E078 0.8728015 0.083655067 0.40780388 0.69021825 22 38169468 38169471 4 - 0.320 0.190 -0.984
ENSG00000184381 E079 0.0000000       22 38180325 38180404 80 -      
ENSG00000184381 E080 0.1265070 0.013048940 0.73725176   22 38181664 38181783 120 - 0.000 0.045 10.722
ENSG00000184381 E081 0.9999378 0.175196884 0.52575311 0.77832587 22 38181784 38181868 85 - 0.320 0.220 -0.721
ENSG00000184381 E082 0.0000000       22 38192033 38192100 68 -      
ENSG00000184381 E083 0.7357511 0.027823744 0.05348491 0.23025666 22 38205293 38205690 398 - 0.420 0.124 -2.306
ENSG00000184381 E084 0.0000000       22 38214453 38214778 326 -      

Help

Please Click HERE to learn more details about the results from DEXseq.