ENSG00000184937

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000332351 ENSG00000184937 No_inf pgKDN_inf WT1 protein_coding protein_coding 16.9695 23.43174 15.87563 0.8290306 1.589229 -0.5613575 3.956419 7.41883 0.7734945 1.085714 0.4467400 -3.245140 0.22673333 0.321050 0.047175 -0.273875 3.992198e-02 1.443889e-07 FALSE TRUE
ENST00000452863 ENSG00000184937 No_inf pgKDN_inf WT1 protein_coding protein_coding 16.9695 23.43174 15.87563 0.8290306 1.589229 -0.5613575 1.675743 0.00000 4.5697141 0.000000 0.9338356 8.839114 0.11645833 0.000000 0.305200 0.305200 1.443889e-07 1.443889e-07 FALSE TRUE
ENST00000651459 ENSG00000184937 No_inf pgKDN_inf WT1 protein_coding nonsense_mediated_decay 16.9695 23.43174 15.87563 0.8290306 1.589229 -0.5613575 1.097689 0.00000 3.2930681 0.000000 1.9030199 8.367663 0.05944167 0.000000 0.178325 0.178325 3.649779e-01 1.443889e-07   FALSE
MSTRG.4574.1 ENSG00000184937 No_inf pgKDN_inf WT1 protein_coding   16.9695 23.43174 15.87563 0.8290306 1.589229 -0.5613575 7.905448 11.95131 5.9004329 1.185545 0.5332994 -1.017039 0.46131667 0.507025 0.376325 -0.130700 5.349578e-01 1.443889e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000184937 E001 0.2448930 0.0163681681 0.670499670   11 32387774 32387774 1 - 0.121 0.074 -0.788
ENSG00000184937 E002 0.3721553 0.2180962037 1.000000000   11 32387775 32387777 3 - 0.121 0.138 0.213
ENSG00000184937 E003 0.3721553 0.2180962037 1.000000000   11 32387778 32387783 6 - 0.121 0.138 0.213
ENSG00000184937 E004 6.9784845 0.0174145287 0.084489305 0.30023598 11 32387784 32387901 118 - 0.741 0.946 0.797
ENSG00000184937 E005 10.7152587 0.0013862117 0.028272098 0.15727027 11 32387902 32388022 121 - 0.907 1.111 0.753
ENSG00000184937 E006 11.9070118 0.0012373136 0.369284233 0.65754295 11 32388023 32388129 107 - 1.040 1.118 0.281
ENSG00000184937 E007 5.4397681 0.0026727518 0.968715360 0.99364123 11 32388130 32388130 1 - 0.789 0.794 0.020
ENSG00000184937 E008 4.9333930 0.0029321542 0.665024356 0.86070800 11 32388131 32388131 1 - 0.789 0.738 -0.203
ENSG00000184937 E009 8.6746357 0.0016596936 0.507033959 0.76561872 11 32388132 32388160 29 - 0.924 0.989 0.243
ENSG00000184937 E010 19.9464803 0.0018091957 0.407605069 0.69007665 11 32388161 32388311 151 - 1.264 1.321 0.199
ENSG00000184937 E011 52.1376020 0.0021817456 0.747195500 0.90015953 11 32388312 32388678 367 - 1.714 1.701 -0.047
ENSG00000184937 E012 50.7484818 0.0004551709 0.430457372 0.70833195 11 32388679 32389041 363 - 1.714 1.682 -0.108
ENSG00000184937 E013 12.0947066 0.0282090349 0.598783958 0.82404311 11 32389042 32389056 15 - 1.132 1.079 -0.191
ENSG00000184937 E014 10.3681750 0.0193719961 0.641440607 0.84774088 11 32389057 32389057 1 - 1.065 1.021 -0.160
ENSG00000184937 E015 16.3422639 0.0100962718 0.711111842 0.88326438 11 32389058 32389091 34 - 1.198 1.231 0.115
ENSG00000184937 E016 17.7660156 0.0070372819 0.125941445 0.37623536 11 32389092 32389179 88 - 1.171 1.293 0.430
ENSG00000184937 E017 3.4627663 0.0105883001 0.916114073 0.97370534 11 32391972 32391980 9 - 0.625 0.639 0.060
ENSG00000184937 E018 8.9123582 0.0157524662 0.754892600 0.90355920 11 32391981 32392064 84 - 0.956 0.989 0.123
ENSG00000184937 E019 0.6353689 0.0154304030 0.080804033 0.29219256 11 32392065 32392665 601 - 0.000 0.286 12.926
ENSG00000184937 E020 10.5431041 0.0015110319 0.345100042 0.63613335 11 32392666 32392755 90 - 0.986 1.072 0.315
ENSG00000184937 E021 0.2537079 0.2504307910 0.559248584   11 32392756 32393228 473 - 0.000 0.138 11.307
ENSG00000184937 E022 0.0000000       11 32396157 32396256 100 -      
ENSG00000184937 E023 16.8508786 0.0008398622 0.485798222 0.74960780 11 32396257 32396365 109 - 1.198 1.250 0.181
ENSG00000184937 E024 10.8891877 0.0013364883 0.953929301 0.98866194 11 32396366 32396407 42 - 1.053 1.058 0.020
ENSG00000184937 E025 1.3265901 0.0176149917 0.017277620 0.11505756 11 32396408 32396982 575 - 0.553 0.193 -2.203
ENSG00000184937 E026 3.1285631 0.0079367177 0.075658402 0.28104968 11 32396983 32398101 1119 - 0.416 0.674 1.212
ENSG00000184937 E027 13.8265717 0.0010533287 0.562127180 0.80212100 11 32399948 32400044 97 - 1.180 1.136 -0.160
ENSG00000184937 E028 0.2537694 0.0159989209 0.495788502   11 32400045 32400145 101 - 0.000 0.138 11.741
ENSG00000184937 E029 1.8956869 0.0092178286 0.007101419 0.06366987 11 32400146 32400615 470 - 0.121 0.557 3.020
ENSG00000184937 E030 0.2346346 0.0156460571 0.104796009   11 32412089 32412264 176 - 0.216 0.000 -13.638
ENSG00000184937 E031 6.3687003 0.0025307451 0.051362112 0.22454115 11 32416490 32416540 51 - 0.971 0.767 -0.788
ENSG00000184937 E032 0.2536433 0.0160575182 0.495561827   11 32416541 32417248 708 - 0.000 0.138 11.741
ENSG00000184937 E033 0.2448930 0.0163681681 0.670499670   11 32417424 32417576 153 - 0.121 0.074 -0.788
ENSG00000184937 E034 10.2307923 0.0013770933 0.418371100 0.69800560 11 32417577 32417654 78 - 1.077 1.006 -0.260
ENSG00000184937 E035 12.3364825 0.0055599650 0.508844280 0.76697835 11 32427956 32428058 103 - 1.142 1.086 -0.203
ENSG00000184937 E036 13.2419736 0.0283202256 0.042107433 0.19968851 11 32428497 32428619 123 - 1.256 1.051 -0.735
ENSG00000184937 E037 0.0000000       11 32428946 32429029 84 -      
ENSG00000184937 E038 0.1186381 0.0118337796 0.302136806   11 32430530 32430813 284 - 0.121 0.000 -12.725
ENSG00000184937 E039 0.9971101 0.0116595664 0.485421668 0.74924207 11 32433765 32433811 47 - 0.216 0.326 0.797
ENSG00000184937 E040 0.6343927 0.0148018191 0.081025541 0.29246631 11 32433936 32434168 233 - 0.000 0.286 12.928
ENSG00000184937 E041 26.3584672 0.0008015199 0.097804741 0.32597975 11 32434700 32435564 865 - 1.476 1.382 -0.325

Help

Please Click HERE to learn more details about the results from DEXseq.