ENSG00000184990

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000329967 ENSG00000184990 No_inf pgKDN_inf SIVA1 protein_coding protein_coding 46.98396 50.89226 45.64394 0.8860147 1.750515 -0.1569904 38.231399 33.118686 42.2720229 1.555669 1.3978481 0.3519634 0.82177500 0.652675 0.92675 0.274075 5.888746e-09 5.888746e-09 FALSE TRUE
ENST00000347067 ENSG00000184990 No_inf pgKDN_inf SIVA1 protein_coding protein_coding 46.98396 50.89226 45.64394 0.8860147 1.750515 -0.1569904 3.207966 8.035130 0.0000000 3.019889 0.0000000 -9.6519720 0.06395000 0.156250 0.00000 -0.156250 1.270732e-02 5.888746e-09 FALSE FALSE
ENST00000556195 ENSG00000184990 No_inf pgKDN_inf SIVA1 protein_coding protein_coding 46.98396 50.89226 45.64394 0.8860147 1.750515 -0.1569904 1.340713 3.507624 0.2392529 1.834951 0.2392529 -3.8189191 0.02623333 0.068525 0.00475 -0.063775 3.773233e-01 5.888746e-09 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000184990 E001 2.2145339 0.0063043522 8.173619e-01 9.336088e-01 14 104753147 104753158 12 + 0.518 0.489 -0.141
ENSG00000184990 E002 2.6950690 0.0050753619 4.386991e-01 7.147413e-01 14 104753159 104753159 1 + 0.619 0.518 -0.463
ENSG00000184990 E003 6.4794815 0.0022715193 1.783645e-01 4.531923e-01 14 104753160 104753170 11 + 0.942 0.808 -0.517
ENSG00000184990 E004 7.7026969 0.0018564740 1.479122e-01 4.094759e-01 14 104753171 104753180 10 + 1.008 0.873 -0.509
ENSG00000184990 E005 12.3368155 0.0012149818 2.852811e-02 1.581059e-01 14 104753181 104753201 21 + 1.210 1.042 -0.606
ENSG00000184990 E006 24.5049295 0.0005903234 3.614778e-05 1.011725e-03 14 104753202 104753319 118 + 1.521 1.291 -0.795
ENSG00000184990 E007 1.1323359 0.0909402186 6.377823e-02 2.542361e-01 14 104753718 104753888 171 + 0.110 0.426 2.537
ENSG00000184990 E008 43.0854767 0.0006078374 3.548693e-04 6.671146e-03 14 104755630 104755824 195 + 1.717 1.571 -0.496
ENSG00000184990 E009 0.7608997 0.0176170949 2.687278e-02 1.522114e-01 14 104755825 104756603 779 + 0.000 0.352 11.267
ENSG00000184990 E010 49.0592311 0.0003230798 2.452042e-01 5.356574e-01 14 104756604 104756760 157 + 1.715 1.675 -0.136
ENSG00000184990 E011 8.3628318 0.0301685750 1.058795e-02 8.340156e-02 14 104756761 104757274 514 + 0.748 1.066 1.210
ENSG00000184990 E012 52.2202501 0.0003207106 1.760066e-20 4.944135e-18 14 104757275 104759427 2153 + 1.438 1.839 1.362
ENSG00000184990 E013 17.6996080 0.0018304005 5.045207e-01 7.636494e-01 14 104759428 104759433 6 + 1.288 1.247 -0.141
ENSG00000184990 E014 40.0133853 0.0003883779 7.751523e-01 9.136359e-01 14 104759434 104759659 226 + 1.609 1.602 -0.025
ENSG00000184990 E015 0.0000000       14 104766790 104766897 108 +      
ENSG00000184990 E016 0.0000000       14 104767864 104768007 144 +      
ENSG00000184990 E017 0.0000000       14 104768392 104768494 103 +      

Help

Please Click HERE to learn more details about the results from DEXseq.