ENSG00000185000

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000524965 ENSG00000185000 No_inf pgKDN_inf DGAT1 protein_coding retained_intron 101.7908 115.2992 88.77902 14.47369 18.02682 -0.3770548 35.344801 40.582313 30.378523 2.4231524 4.4120702 -0.4176800 0.36261667 0.367150 0.361725 -0.005425 1.00000000 0.04668131 TRUE TRUE
ENST00000528718 ENSG00000185000 No_inf pgKDN_inf DGAT1 protein_coding protein_coding 101.7908 115.2992 88.77902 14.47369 18.02682 -0.3770548 6.595885 7.319623 5.724152 0.4976573 0.2342883 -0.3541589 0.06947500 0.065925 0.070275 0.004350 0.99526762 0.04668131 FALSE TRUE
ENST00000531896 ENSG00000185000 No_inf pgKDN_inf DGAT1 protein_coding retained_intron 101.7908 115.2992 88.77902 14.47369 18.02682 -0.3770548 8.098490 15.013605 1.652892 1.2652869 0.8399735 -3.1754643 0.07773333 0.137375 0.022875 -0.114500 0.04668131 0.04668131 FALSE TRUE
ENST00000611213 ENSG00000185000 No_inf pgKDN_inf DGAT1 protein_coding miRNA 101.7908 115.2992 88.77902 14.47369 18.02682 -0.3770548 20.991248 30.284088 17.171872 17.4847095 17.1718716 -0.8181491 0.14683333 0.216250 0.120400 -0.095850 0.86108537 0.04668131   FALSE
MSTRG.28367.3 ENSG00000185000 No_inf pgKDN_inf DGAT1 protein_coding   101.7908 115.2992 88.77902 14.47369 18.02682 -0.3770548 19.240335 4.438723 23.655561 2.5634537 4.6163771 2.4113259 0.22312500 0.042125 0.311600 0.269475 0.09106973 0.04668131 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000185000 E001 0.0000000       8 144314584 144314589 6 -      
ENSG00000185000 E002 1.8628975 0.3123464204 3.343603e-01 6.261958e-01 8 144314590 144314820 231 - 0.307 0.551 1.311
ENSG00000185000 E003 3.0994554 0.0049276113 1.269472e-01 3.776695e-01 8 144314821 144314925 105 - 0.486 0.695 0.939
ENSG00000185000 E004 33.1507188 0.0028385903 9.770338e-04 1.475234e-02 8 144314926 144316319 1394 - 1.419 1.608 0.646
ENSG00000185000 E005 9.6275172 0.0019295611 1.882745e-01 4.666388e-01 8 144316320 144316324 5 - 0.954 1.077 0.452
ENSG00000185000 E006 129.9006536 0.0002047112 4.887565e-01 7.519567e-01 8 144316325 144316709 385 - 2.104 2.125 0.070
ENSG00000185000 E007 0.2537079 0.2503402955 3.389665e-01   8 144316843 144316852 10 - 0.000 0.166 10.915
ENSG00000185000 E008 49.5263217 0.0016309012 6.926188e-01 8.741897e-01 8 144316853 144316915 63 - 1.710 1.695 -0.048
ENSG00000185000 E009 35.2324290 0.0020096112 2.195695e-01 5.062430e-01 8 144317022 144317074 53 - 1.590 1.529 -0.208
ENSG00000185000 E010 30.3302078 0.0134726928 8.329007e-01 9.397445e-01 8 144317075 144317096 22 - 1.486 1.501 0.050
ENSG00000185000 E011 27.5265608 0.0006653640 6.113906e-01 8.308705e-01 8 144317097 144317109 13 - 1.436 1.468 0.110
ENSG00000185000 E012 13.2502500 0.0025385911 9.720773e-03 7.887471e-02 8 144317110 144317186 77 - 1.023 1.237 0.772
ENSG00000185000 E013 42.0163920 0.0003827171 3.303244e-01 6.228533e-01 8 144317187 144317245 59 - 1.654 1.613 -0.140
ENSG00000185000 E014 25.1499639 0.0005376553 8.716707e-01 9.559505e-01 8 144317246 144317252 7 - 1.419 1.413 -0.021
ENSG00000185000 E015 1.0987170 0.0126662573 6.230961e-01 8.377347e-01 8 144317253 144317315 63 - 0.360 0.286 -0.470
ENSG00000185000 E016 64.3676463 0.0002753492 1.012798e-01 3.322845e-01 8 144317333 144317445 113 - 1.844 1.787 -0.192
ENSG00000185000 E017 2.5965087 0.2057580873 5.737647e-01 8.090198e-01 8 144317446 144317543 98 - 0.486 0.604 0.550
ENSG00000185000 E018 43.0178888 0.0004097057 4.517747e-02 2.077939e-01 8 144317544 144317588 45 - 1.687 1.600 -0.296
ENSG00000185000 E019 3.0776720 0.0590804422 7.611127e-01 9.066982e-01 8 144317589 144317633 45 - 0.584 0.629 0.200
ENSG00000185000 E020 36.1865326 0.0006091091 1.006666e-01 3.312130e-01 8 144317671 144317712 42 - 1.609 1.532 -0.265
ENSG00000185000 E021 38.4875155 0.0004648278 6.787924e-01 8.671038e-01 8 144317784 144317822 39 - 1.604 1.587 -0.056
ENSG00000185000 E022 28.7774990 0.0071718967 3.319490e-01 6.241257e-01 8 144317914 144317916 3 - 1.436 1.501 0.224
ENSG00000185000 E023 65.3387712 0.0006083092 4.718718e-01 7.391473e-01 8 144317917 144318017 101 - 1.804 1.834 0.102
ENSG00000185000 E024 0.2541163 0.0159963455 2.823598e-01   8 144318094 144318094 1 - 0.000 0.166 11.726
ENSG00000185000 E025 53.6604848 0.0002700388 3.790243e-01 6.658728e-01 8 144318095 144318169 75 - 1.753 1.721 -0.109
ENSG00000185000 E026 4.7970147 0.0031225970 1.419164e-07 7.981354e-06 8 144318170 144318260 91 - 0.249 0.961 3.396
ENSG00000185000 E027 59.2120446 0.0003044078 4.165884e-01 6.964317e-01 8 144318261 144318362 102 - 1.793 1.765 -0.094
ENSG00000185000 E028 1.7408223 0.0129706806 1.618099e-01 4.300951e-01 8 144318363 144318460 98 - 0.308 0.522 1.174
ENSG00000185000 E029 73.4788419 0.0022833172 7.659216e-01 9.090536e-01 8 144318461 144318566 106 - 1.875 1.867 -0.028
ENSG00000185000 E030 38.4138856 0.0004961399 9.228090e-01 9.763295e-01 8 144318699 144318751 53 - 1.590 1.598 0.027
ENSG00000185000 E031 43.4486754 0.0082153233 2.766791e-01 5.701383e-01 8 144318835 144318920 86 - 1.610 1.675 0.221
ENSG00000185000 E032 35.9475202 0.0163730136 3.753126e-01 6.628498e-01 8 144319028 144319068 41 - 1.532 1.593 0.208
ENSG00000185000 E033 38.4743500 0.0004250901 5.052286e-01 7.641303e-01 8 144321321 144321408 88 - 1.575 1.610 0.120
ENSG00000185000 E034 47.2893218 0.0003916152 1.775923e-04 3.796378e-03 8 144326437 144326910 474 - 1.761 1.603 -0.537

Help

Please Click HERE to learn more details about the results from DEXseq.