ENSG00000185024

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000392557 ENSG00000185024 No_inf pgKDN_inf BRF1 protein_coding protein_coding 14.99708 16.43719 13.06016 1.288444 0.4842526 -0.3315642 1.1229713 1.8961615 0.8749324 0.5777684 0.3227833 -1.1070312 0.07537500 0.118650 0.068125 -0.050525 0.83308949 0.01549444 FALSE TRUE
ENST00000446501 ENSG00000185024 No_inf pgKDN_inf BRF1 protein_coding protein_coding 14.99708 16.43719 13.06016 1.288444 0.4842526 -0.3315642 4.8244838 3.2582106 5.2509752 1.1667011 0.5278471 0.6868293 0.32921667 0.192450 0.400400 0.207950 0.51844523 0.01549444 FALSE TRUE
ENST00000547530 ENSG00000185024 No_inf pgKDN_inf BRF1 protein_coding protein_coding 14.99708 16.43719 13.06016 1.288444 0.4842526 -0.3315642 2.5270207 3.3583348 0.8549766 1.1284108 0.8549766 -1.9613025 0.16676667 0.221750 0.061475 -0.160275 0.40353095 0.01549444 FALSE TRUE
ENST00000549044 ENSG00000185024 No_inf pgKDN_inf BRF1 protein_coding protein_coding_CDS_not_defined 14.99708 16.43719 13.06016 1.288444 0.4842526 -0.3315642 0.9595434 0.9843438 0.4825000 0.9843438 0.4825000 -1.0136211 0.05623333 0.048575 0.034700 -0.013875 1.00000000 0.01549444 FALSE FALSE
ENST00000635152 ENSG00000185024 No_inf pgKDN_inf BRF1 protein_coding retained_intron 14.99708 16.43719 13.06016 1.288444 0.4842526 -0.3315642 1.9387028 4.0238667 0.6752844 0.3330100 0.4461123 -2.5573887 0.12452500 0.251600 0.054750 -0.196850 0.08433482 0.01549444 FALSE TRUE
MSTRG.9151.4 ENSG00000185024 No_inf pgKDN_inf BRF1 protein_coding   14.99708 16.43719 13.06016 1.288444 0.4842526 -0.3315642 1.6744248 0.0000000 3.7368083 0.0000000 1.4054876 8.5495184 0.12444167 0.000000 0.289575 0.289575 0.01549444 0.01549444 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000185024 E001 0.1187032 0.0118945773 3.861540e-01   14 105209286 105209288 3 - 0.110 0.000 -10.228
ENSG00000185024 E002 7.6420543 0.0025641983 9.934470e-01 1.0000000000 14 105209289 105209428 140 - 0.928 0.929 0.003
ENSG00000185024 E003 8.8682472 0.0037178085 8.619031e-01 0.9522282955 14 105209429 105209495 67 - 0.997 0.979 -0.063
ENSG00000185024 E004 17.2801971 0.0008324014 9.291234e-02 0.3166593507 14 105209496 105209659 164 - 1.319 1.204 -0.405
ENSG00000185024 E005 37.4088070 0.0004413872 2.128524e-01 0.4980230095 14 105209660 105210077 418 - 1.540 1.599 0.202
ENSG00000185024 E006 31.2288980 0.0011236449 3.468014e-01 0.6374611773 14 105210078 105210277 200 - 1.470 1.519 0.171
ENSG00000185024 E007 16.5695415 0.0009389933 2.694926e-01 0.5631466817 14 105210278 105210366 89 - 1.282 1.204 -0.274
ENSG00000185024 E008 20.6431765 0.0007642958 3.882354e-01 0.6741063167 14 105210367 105210588 222 - 1.359 1.304 -0.191
ENSG00000185024 E009 16.0822239 0.0098009107 4.266945e-01 0.7053128207 14 105211122 105211293 172 - 1.262 1.198 -0.224
ENSG00000185024 E010 4.1523946 0.0034846822 1.870230e-04 0.0039540968 14 105211294 105212112 819 - 0.333 0.847 2.391
ENSG00000185024 E011 9.0001513 0.0015466274 8.767988e-01 0.9582424961 14 105212113 105212164 52 - 0.984 0.998 0.053
ENSG00000185024 E012 0.7527786 0.0150628845 1.923927e-01 0.4722819700 14 105212165 105213428 1264 - 0.110 0.310 1.855
ENSG00000185024 E013 0.7455129 0.0486487325 6.750759e-01 0.8653897275 14 105217213 105217278 66 - 0.197 0.263 0.533
ENSG00000185024 E014 12.2790141 0.0012176439 7.625519e-02 0.2822993811 14 105217544 105217632 89 - 1.021 1.169 0.533
ENSG00000185024 E015 17.1313546 0.0008373849 9.490830e-01 0.9867620019 14 105217633 105217800 168 - 1.248 1.252 0.015
ENSG00000185024 E016 10.5107155 0.0014186520 2.983277e-01 0.5912999592 14 105218998 105219053 56 - 0.997 1.088 0.334
ENSG00000185024 E017 11.7199870 0.0089202163 7.254577e-01 0.8898233518 14 105219151 105219232 82 - 1.077 1.110 0.118
ENSG00000185024 E018 0.4801542 0.5339806488 4.280267e-01   14 105219233 105219298 66 - 0.270 0.082 -2.050
ENSG00000185024 E019 1.2522267 0.1327931836 2.184583e-01 0.5050723736 14 105219299 105220068 770 - 0.197 0.426 1.533
ENSG00000185024 E020 7.4389595 0.0025940900 1.726778e-01 0.4455011721 14 105220069 105220127 59 - 0.830 0.970 0.533
ENSG00000185024 E021 3.8841151 0.0042987651 7.996415e-03 0.0691262469 14 105220128 105220130 3 - 0.436 0.793 1.592
ENSG00000185024 E022 19.9664405 0.0007985669 8.668336e-01 0.9541242990 14 105221648 105221884 237 - 1.307 1.318 0.037
ENSG00000185024 E023 6.2963333 0.0070031499 6.887773e-01 0.8718262321 14 105221885 105221914 30 - 0.830 0.872 0.166
ENSG00000185024 E024 5.1586875 0.0031649591 3.308652e-05 0.0009380796 14 105221915 105222545 631 - 0.387 0.929 2.381
ENSG00000185024 E025 5.5151364 0.0564608039 4.612861e-01 0.7320811160 14 105226069 105226102 34 - 0.865 0.763 -0.403
ENSG00000185024 E026 4.7807058 0.0976459318 4.873926e-01 0.7509012968 14 105226103 105226113 11 - 0.811 0.713 -0.392
ENSG00000185024 E027 5.0154055 0.0816381665 3.324076e-01 0.6245373405 14 105226114 105226122 9 - 0.848 0.713 -0.537
ENSG00000185024 E028 6.2603643 0.0833666994 5.470670e-01 0.7926211047 14 105226123 105226161 39 - 0.898 0.821 -0.297
ENSG00000185024 E029 7.1577013 0.0021437550 1.470697e-03 0.0201321259 14 105226251 105226290 40 - 1.066 0.747 -1.217
ENSG00000185024 E030 8.9691175 0.0016183346 5.815404e-01 0.8135291018 14 105226634 105226760 127 - 1.021 0.970 -0.189
ENSG00000185024 E031 0.7623489 0.2138171049 5.488156e-02 0.2333266789 14 105226761 105228270 1510 - 0.000 0.352 13.606
ENSG00000185024 E032 3.4634268 0.0043461320 5.015588e-01 0.7615086558 14 105228820 105228860 41 - 0.589 0.676 0.381
ENSG00000185024 E033 4.3089764 0.0314796240 9.114237e-01 0.9717929946 14 105228861 105228913 53 - 0.726 0.713 -0.051
ENSG00000185024 E034 3.8017759 0.0046491351 4.792480e-01 0.7450775912 14 105241265 105241304 40 - 0.726 0.637 -0.374
ENSG00000185024 E035 7.4409242 0.0019111016 3.162658e-02 0.1680209056 14 105241305 105241414 110 - 1.033 0.821 -0.799
ENSG00000185024 E036 0.4894115 0.0158105117 7.494010e-01   14 105241415 105242605 1191 - 0.197 0.151 -0.467
ENSG00000185024 E037 1.7344645 0.1269194535 7.047516e-01 0.8800487057 14 105247071 105247287 217 - 0.387 0.459 0.382
ENSG00000185024 E038 6.1989005 0.0025106222 2.495159e-01 0.5404750433 14 105247288 105248074 787 - 0.770 0.896 0.490
ENSG00000185024 E039 1.3539032 0.0109580447 8.196875e-01 0.9344739325 14 105248075 105249148 1074 - 0.387 0.352 -0.204
ENSG00000185024 E040 0.0000000       14 105249149 105249404 256 -      
ENSG00000185024 E041 3.2866842 0.0050850361 7.484082e-02 0.2790897433 14 105252507 105252514 8 - 0.748 0.517 -1.007
ENSG00000185024 E042 4.5198109 0.0036625733 1.438821e-01 0.4039004034 14 105252515 105252579 65 - 0.830 0.657 -0.701
ENSG00000185024 E043 0.7368887 0.0623895251 7.050312e-01 0.8801566345 14 105256186 105256517 332 - 0.270 0.211 -0.467
ENSG00000185024 E044 4.0793441 0.0036258852 5.129154e-01 0.7698669822 14 105256518 105256549 32 - 0.649 0.730 0.341
ENSG00000185024 E045 7.4878300 0.0025916879 5.422187e-01 0.7895681250 14 105272721 105272894 174 - 0.957 0.896 -0.230
ENSG00000185024 E046 3.8924100 0.0541015061 9.742924e-02 0.3252103365 14 105286296 105286376 81 - 0.811 0.569 -1.015
ENSG00000185024 E047 3.6857841 0.0191496714 6.435065e-01 0.8488648617 14 105300446 105301278 833 - 0.701 0.637 -0.274
ENSG00000185024 E048 0.0000000       14 105315322 105315341 20 -      
ENSG00000185024 E049 0.1272623 0.0123598998 7.448389e-01   14 105315342 105315589 248 - 0.000 0.082 11.620

Help

Please Click HERE to learn more details about the results from DEXseq.