ENSG00000185291

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000331035 ENSG00000185291 No_inf pgKDN_inf IL3RA protein_coding protein_coding 21.43193 26.00332 13.50619 1.572306 3.875526 -0.9445617 6.5265585 12.5979688 1.4835823 2.5755108 1.4835823 -3.0774872 0.32625833 0.496800 0.137250 -0.359550 0.053988272 0.002841003 FALSE TRUE
ENST00000381469 ENSG00000185291 No_inf pgKDN_inf IL3RA protein_coding protein_coding 21.43193 26.00332 13.50619 1.572306 3.875526 -0.9445617 0.5949136 0.6162522 1.1684887 0.6162522 0.6989057 0.9121222 0.04617500 0.020850 0.117675 0.096825 0.723962011 0.002841003 FALSE TRUE
ENST00000432757 ENSG00000185291 No_inf pgKDN_inf IL3RA protein_coding protein_coding 21.43193 26.00332 13.50619 1.572306 3.875526 -0.9445617 2.0260833 0.0000000 2.7015297 0.0000000 0.9738029 8.0829632 0.13534167 0.000000 0.190275 0.190275 0.002841003 0.002841003 FALSE FALSE
MSTRG.29665.1 ENSG00000185291 No_inf pgKDN_inf IL3RA protein_coding   21.43193 26.00332 13.50619 1.572306 3.875526 -0.9445617 1.8130432 3.1673220 0.9612541 1.2760242 0.6072188 -1.7098906 0.10151667 0.131800 0.085975 -0.045825 0.847127383 0.002841003 FALSE TRUE
MSTRG.29665.4 ENSG00000185291 No_inf pgKDN_inf IL3RA protein_coding   21.43193 26.00332 13.50619 1.572306 3.875526 -0.9445617 2.1761722 4.4556954 1.2524992 1.5894025 0.7962291 -1.8226024 0.12015000 0.165625 0.134675 -0.030950 0.812851907 0.002841003 FALSE TRUE
MSTRG.29665.6 ENSG00000185291 No_inf pgKDN_inf IL3RA protein_coding   21.43193 26.00332 13.50619 1.572306 3.875526 -0.9445617 1.0219707 3.0659121 0.0000000 1.7750200 0.0000000 -8.2648705 0.03581667 0.107450 0.000000 -0.107450 0.621768265 0.002841003 FALSE FALSE
MSTRG.29665.8 ENSG00000185291 No_inf pgKDN_inf IL3RA protein_coding   21.43193 26.00332 13.50619 1.572306 3.875526 -0.9445617 1.4727648 1.8006240 1.3168122 0.6823677 0.3501847 -0.4485228 0.08826667 0.066700 0.118400 0.051700 0.821241864 0.002841003 TRUE TRUE
MSTRG.29665.9 ENSG00000185291 No_inf pgKDN_inf IL3RA protein_coding   21.43193 26.00332 13.50619 1.572306 3.875526 -0.9445617 5.4956907 0.0000000 4.0073663 0.0000000 4.0073663 8.6501062 0.12489167 0.000000 0.161775 0.161775 0.747729245 0.002841003   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000185291 E001 0.3806233 0.0158977065 0.8272719045   X 1336611 1336615 5 + 0.001 0.138 8.312
ENSG00000185291 E002 0.5074773 0.0158852730 0.5183394559 0.773465035 X 1336616 1336631 16 + 0.000 0.176 10.790
ENSG00000185291 E003 1.1121300 0.0336720791 0.3921139271 0.677134751 X 1336632 1336686 55 + 0.387 0.243 -0.938
ENSG00000185291 E004 2.3650197 0.0079959818 0.5630190444 0.802605011 X 1336687 1336784 98 + 0.531 0.439 -0.452
ENSG00000185291 E005 2.1426275 0.2072752745 0.5532079698 0.796353864 X 1336785 1336795 11 + 0.292 0.459 0.970
ENSG00000185291 E006 13.8370700 0.0011526918 0.1619455180 0.430243317 X 1336796 1336926 131 + 1.173 1.051 -0.438
ENSG00000185291 E007 0.3625236 0.1344301998 0.0995235048   X 1341603 1341727 125 + 0.292 0.051 -2.937
ENSG00000185291 E008 2.6845522 0.0052858853 0.0005327402 0.009173949 X 1341728 1341730 3 + 0.829 0.352 -2.201
ENSG00000185291 E009 11.7393431 0.0014227476 0.5196244415 0.774300935 X 1341731 1341829 99 + 1.062 1.000 -0.227
ENSG00000185291 E010 12.5434250 0.0011166194 0.3372980519 0.629083378 X 1345316 1345372 57 + 0.961 1.056 0.350
ENSG00000185291 E011 12.4158122 0.0029006574 0.3655954438 0.654063932 X 1345373 1345434 62 + 0.961 1.051 0.332
ENSG00000185291 E012 12.4518097 0.0050777342 0.1407294032 0.399017390 X 1348431 1348545 115 + 1.144 1.006 -0.503
ENSG00000185291 E013 0.7529084 0.0509041719 0.8832797185 0.960711645 X 1349053 1349099 47 + 0.170 0.211 0.384
ENSG00000185291 E014 0.8608079 0.5110422767 0.4440082499 0.718658572 X 1352045 1352099 55 + 0.387 0.176 -1.521
ENSG00000185291 E015 15.1980729 0.0009736165 0.1350750553 0.390787266 X 1352100 1352232 133 + 1.213 1.088 -0.446
ENSG00000185291 E016 0.6069811 0.0150971181 0.0572232118 0.239060938 X 1352233 1352321 89 + 0.387 0.097 -2.523
ENSG00000185291 E017 3.6126840 0.0098453211 0.3816827481 0.668080525 X 1352322 1352324 3 + 0.684 0.559 -0.545
ENSG00000185291 E018 8.6296282 0.0045847459 0.8322755502 0.939487097 X 1352325 1352506 182 + 0.913 0.889 -0.090
ENSG00000185291 E019 18.2939286 0.0009455050 0.4872337777 0.750828834 X 1356221 1356336 116 + 1.144 1.201 0.202
ENSG00000185291 E020 10.6521809 0.0013651496 0.4683869357 0.736548613 X 1358861 1358887 27 + 0.913 0.989 0.285
ENSG00000185291 E021 1.6230370 0.0088590709 0.8367650882 0.941518200 X 1363741 1363788 48 + 0.387 0.352 -0.201
ENSG00000185291 E022 22.4813218 0.0009033325 0.0448264895 0.207045636 X 1365138 1365252 115 + 1.144 1.301 0.555
ENSG00000185291 E023 23.5982622 0.0006060333 0.0825532765 0.295946125 X 1378659 1378764 106 + 1.187 1.317 0.459
ENSG00000185291 E024 16.3363097 0.0012391056 0.0379780138 0.188025978 X 1381023 1381104 82 + 0.983 1.176 0.700
ENSG00000185291 E025 35.9695038 0.0005017838 0.4084941369 0.690779544 X 1382391 1383178 788 + 1.507 1.461 -0.159

Help

Please Click HERE to learn more details about the results from DEXseq.