ENSG00000185404

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000243810 ENSG00000185404 No_inf pgKDN_inf SP140L protein_coding protein_coding 24.65451 22.75238 26.96175 0.6594219 2.41195 0.2447975 1.2999939 0.0000000 1.04430268 0.0000000 1.04430268 6.72014530 0.05575000 0.000000 0.047300 0.047300 0.861085367 0.003864218 FALSE  
ENST00000415673 ENSG00000185404 No_inf pgKDN_inf SP140L protein_coding protein_coding 24.65451 22.75238 26.96175 0.6594219 2.41195 0.2447975 9.9833251 7.2755578 11.01662348 0.6910747 0.88358984 0.59787975 0.41085000 0.320575 0.409850 0.089275 0.659561187 0.003864218 FALSE  
ENST00000462156 ENSG00000185404 No_inf pgKDN_inf SP140L protein_coding retained_intron 24.65451 22.75238 26.96175 0.6594219 2.41195 0.2447975 5.2113126 5.8632961 6.27703877 0.6871048 2.91571592 0.09821029 0.19718333 0.257700 0.211025 -0.046675 0.842318136 0.003864218    
ENST00000483728 ENSG00000185404 No_inf pgKDN_inf SP140L protein_coding retained_intron 24.65451 22.75238 26.96175 0.6594219 2.41195 0.2447975 0.6055314 1.3995185 0.04344435 0.1257464 0.04344435 -4.72102131 0.02633333 0.061200 0.001975 -0.059225 0.003864218 0.003864218 TRUE  
MSTRG.17723.11 ENSG00000185404 No_inf pgKDN_inf SP140L protein_coding   24.65451 22.75238 26.96175 0.6594219 2.41195 0.2447975 3.4238749 4.3234353 3.77699979 1.3381433 1.59588617 -0.19445582 0.13901667 0.190475 0.144250 -0.046225 0.846090574 0.003864218 FALSE  
MSTRG.17723.5 ENSG00000185404 No_inf pgKDN_inf SP140L protein_coding   24.65451 22.75238 26.96175 0.6594219 2.41195 0.2447975 1.1418148 0.4844288 2.43784531 0.3139775 1.40046135 2.30767757 0.04609167 0.022150 0.099175 0.077025 0.779627977 0.003864218 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000185404 E001 0.2438580 0.0163092918 8.431447e-01   2 230327184 230327192 9 + 0.083 0.109 0.433
ENSG00000185404 E002 0.4795651 0.0224898302 4.588187e-01   2 230327193 230327212 20 + 0.213 0.109 -1.151
ENSG00000185404 E003 0.6064191 0.2045820043 8.773909e-01 0.958435138 2 230327213 230327217 5 + 0.213 0.196 -0.151
ENSG00000185404 E004 1.0875533 0.2616460837 5.644029e-01 0.803582411 2 230327218 230327230 13 + 0.355 0.268 -0.566
ENSG00000185404 E005 2.0661891 0.0079777544 8.374760e-01 0.941771287 2 230327231 230327269 39 + 0.492 0.476 -0.081
ENSG00000185404 E006 2.7945421 0.0057868189 6.612466e-01 0.858656670 2 230327270 230327301 32 + 0.596 0.551 -0.204
ENSG00000185404 E007 5.4789446 0.0029708972 8.437034e-01 0.944147477 2 230328757 230328831 75 + 0.811 0.806 -0.019
ENSG00000185404 E008 0.0000000       2 230342070 230342173 104 +      
ENSG00000185404 E009 11.4886216 0.0012594880 4.092094e-01 0.691382151 2 230357805 230357967 163 + 1.054 1.140 0.311
ENSG00000185404 E010 12.5653518 0.0013730325 8.405450e-01 0.942807459 2 230358964 230359132 169 + 1.114 1.149 0.124
ENSG00000185404 E011 6.5806388 0.0027197260 8.720956e-01 0.956241402 2 230361614 230361697 84 + 0.877 0.877 0.003
ENSG00000185404 E012 0.3533378 0.0159000420 1.617492e-01   2 230370857 230370905 49 + 0.213 0.000 -12.226
ENSG00000185404 E013 0.3533378 0.0159000420 1.617492e-01   2 230370906 230370907 2 + 0.213 0.000 -12.226
ENSG00000185404 E014 8.5780431 0.0022518368 2.899692e-01 0.583654214 2 230370908 230370967 60 + 0.923 1.040 0.433
ENSG00000185404 E015 9.3744718 0.0015607070 7.084922e-01 0.881838315 2 230371598 230371651 54 + 1.020 1.004 -0.058
ENSG00000185404 E016 1.8518494 0.0266679258 2.236240e-01 0.511185043 2 230371652 230372744 1093 + 0.355 0.551 1.018
ENSG00000185404 E017 9.9105564 0.0017771925 2.641898e-02 0.150677023 2 230383510 230383575 66 + 1.107 0.924 -0.674
ENSG00000185404 E018 7.3646452 0.0020776232 2.307198e-02 0.138570619 2 230385224 230385240 17 + 1.002 0.787 -0.823
ENSG00000185404 E019 11.0074776 0.0118788111 3.527778e-02 0.179821158 2 230385241 230385304 64 + 1.148 0.966 -0.663
ENSG00000185404 E020 9.6080988 0.0016875827 4.248389e-01 0.703999374 2 230388559 230388633 75 + 1.046 0.992 -0.197
ENSG00000185404 E021 1.1069979 0.0104560015 4.791865e-01 0.745053845 2 230388634 230388786 153 + 0.265 0.384 0.755
ENSG00000185404 E022 10.3853809 0.0015485063 6.808845e-01 0.868167148 2 230389919 230390023 105 + 1.029 1.083 0.195
ENSG00000185404 E023 0.9978004 0.0115963209 7.448809e-02 0.278296200 2 230391700 230391714 15 + 0.153 0.432 2.018
ENSG00000185404 E024 2.7022426 0.0067703044 3.120331e-01 0.605388460 2 230391715 230391807 93 + 0.492 0.645 0.696
ENSG00000185404 E025 16.0045649 0.0011004749 5.566143e-02 0.235048817 2 230392087 230392229 143 + 1.277 1.157 -0.421
ENSG00000185404 E026 8.0122291 0.0121118429 3.719904e-01 0.659872385 2 230393414 230393461 48 + 0.984 0.909 -0.280
ENSG00000185404 E027 9.4603229 0.0017663349 2.439570e-01 0.533970804 2 230396757 230396798 42 + 1.054 0.966 -0.323
ENSG00000185404 E028 1.8582384 0.0079981287 7.597835e-02 0.281636843 2 230399821 230400126 306 + 0.312 0.585 1.433
ENSG00000185404 E029 15.9534618 0.0009316162 8.294925e-01 0.938244459 2 230400127 230400242 116 + 1.225 1.229 0.012
ENSG00000185404 E030 0.9886156 0.0480775706 3.047123e-01 0.598069627 2 230400243 230400333 91 + 0.213 0.384 1.170
ENSG00000185404 E031 1.7493576 0.1235702621 3.332361e-02 0.173498937 2 230400334 230400413 80 + 0.213 0.616 2.308
ENSG00000185404 E032 2.5294219 0.0538674287 7.544502e-06 0.000267877 2 230400414 230400954 541 + 0.083 0.806 4.681
ENSG00000185404 E033 5.0785027 0.0043923391 1.774008e-01 0.451999822 2 230400955 230400981 27 + 0.839 0.697 -0.567
ENSG00000185404 E034 4.0064573 0.0785459954 6.490459e-01 0.852073730 2 230400982 230401063 82 + 0.717 0.672 -0.188
ENSG00000185404 E035 0.0000000       2 230401064 230401130 67 +      
ENSG00000185404 E036 0.3812526 0.0158876982 6.279243e-02   2 230401131 230401365 235 + 0.000 0.268 12.065
ENSG00000185404 E037 0.0000000       2 230401366 230401443 78 +      
ENSG00000185404 E038 0.0000000       2 230401444 230401663 220 +      
ENSG00000185404 E039 4.3573038 0.0033855935 2.074540e-01 0.491017916 2 230401664 230401807 144 + 0.782 0.645 -0.567
ENSG00000185404 E040 82.3183549 0.0175724687 1.177677e-01 0.362497462 2 230402798 230403732 935 + 1.872 1.969 0.326

Help

Please Click HERE to learn more details about the results from DEXseq.