ENSG00000185420

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000483072 ENSG00000185420 No_inf pgKDN_inf SMYD3 protein_coding protein_coding_CDS_not_defined 33.63878 56.71178 24.3817 1.534049 1.252312 -1.217512 3.331022 7.833780 1.3295593 2.307037 1.3295593 -2.5497907 0.07433333 0.136775 0.048075 -0.088700 0.181810278 0.009916168   FALSE
ENST00000490107 ENSG00000185420 No_inf pgKDN_inf SMYD3 protein_coding protein_coding 33.63878 56.71178 24.3817 1.534049 1.252312 -1.217512 4.227450 1.801638 6.1489651 1.801638 0.6134488 1.7653931 0.17389167 0.030625 0.255300 0.224675 0.009916168 0.009916168 FALSE TRUE
MSTRG.2971.1 ENSG00000185420 No_inf pgKDN_inf SMYD3 protein_coding   33.63878 56.71178 24.3817 1.534049 1.252312 -1.217512 8.834988 11.084409 6.6751985 3.874983 1.0576240 -0.7307905 0.30471667 0.190900 0.282250 0.091350 0.829478471 0.009916168 FALSE TRUE
MSTRG.2971.6 ENSG00000185420 No_inf pgKDN_inf SMYD3 protein_coding   33.63878 56.71178 24.3817 1.534049 1.252312 -1.217512 12.732435 27.133973 8.6157831 3.500479 1.7542731 -1.6539045 0.31903333 0.484425 0.346000 -0.138425 0.648100068 0.009916168 FALSE TRUE
MSTRG.2971.7 ENSG00000185420 No_inf pgKDN_inf SMYD3 protein_coding   33.63878 56.71178 24.3817 1.534049 1.252312 -1.217512 2.602103 6.279810 0.4093053 2.106775 0.2376620 -3.9069436 0.06205000 0.112275 0.016000 -0.096275 0.502063539 0.009916168 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000185420 E001 0.1272623 0.0124057948 1.0000000000   1 245749293 245749341 49 - 0.000 0.065 9.889
ENSG00000185420 E002 0.1272623 0.0124057948 1.0000000000   1 245749342 245749344 3 - 0.000 0.065 11.960
ENSG00000185420 E003 0.2541163 0.0159833956 0.7328068880   1 245749345 245749346 2 - 0.000 0.121 12.883
ENSG00000185420 E004 1.3691092 0.0095258059 0.8555115719 0.949167023 1 245749347 245749350 4 - 0.327 0.358 0.192
ENSG00000185420 E005 1.7496066 0.0080685865 0.4841814659 0.748399991 1 245749351 245749359 9 - 0.327 0.441 0.651
ENSG00000185420 E006 2.6380845 0.0142465801 0.1042728951 0.337444757 1 245749360 245749366 7 - 0.327 0.589 1.362
ENSG00000185420 E007 57.5298977 0.0002935971 0.1650061906 0.434521942 1 245749367 245749664 298 - 1.679 1.740 0.207
ENSG00000185420 E008 36.0587925 0.0005440974 0.7533240138 0.902898822 1 245764041 245764149 109 - 1.511 1.531 0.071
ENSG00000185420 E009 0.0000000       1 245788861 245788942 82 -      
ENSG00000185420 E010 0.7621886 0.5213047070 0.3336364837 0.625659408 1 245814342 245814415 74 - 0.000 0.293 13.713
ENSG00000185420 E011 13.9801227 0.0515755156 0.2539135181 0.545529629 1 245858496 245858497 2 - 1.030 1.170 0.503
ENSG00000185420 E012 27.0853723 0.0015135938 0.0374406328 0.186439211 1 245858498 245858561 64 - 1.303 1.441 0.479
ENSG00000185420 E013 34.5610259 0.0004807357 0.0315184143 0.167578288 1 245858562 245858670 109 - 1.416 1.540 0.425
ENSG00000185420 E014 15.6041967 0.0037685485 0.1072011902 0.343071797 1 245863799 245863808 10 - 1.074 1.214 0.504
ENSG00000185420 E015 29.4805011 0.0005113527 0.5972858500 0.823193086 1 245863809 245863886 78 - 1.416 1.451 0.120
ENSG00000185420 E016 32.0782280 0.0004752553 0.0004704129 0.008326633 1 245915530 245915640 111 - 1.597 1.417 -0.615
ENSG00000185420 E017 31.0758681 0.0004697491 0.0851750635 0.301749335 1 245927931 245928033 103 - 1.526 1.436 -0.309
ENSG00000185420 E018 15.6555787 0.0010072056 0.9247877520 0.977150746 1 245929870 245929897 28 - 1.182 1.179 -0.012
ENSG00000185420 E019 16.8104843 0.0010259104 0.4206447082 0.699875596 1 245929898 245929937 40 - 1.160 1.227 0.236
ENSG00000185420 E020 0.2452102 0.0164872200 0.5025944153   1 245929938 245930823 886 - 0.138 0.065 -1.223
ENSG00000185420 E021 0.1271363 0.0125160602 1.0000000000   1 245953231 245953355 125 - 0.000 0.065 11.959
ENSG00000185420 E022 0.0000000       1 245955833 245956102 270 -      
ENSG00000185420 E023 0.1187032 0.0118251246 0.2081174579   1 245988394 245988562 169 - 0.138 0.000 -14.583
ENSG00000185420 E024 0.6182469 0.0144876991 0.6287202055 0.840723572 1 246052557 246053069 513 - 0.243 0.170 -0.638
ENSG00000185420 E025 0.5078857 0.0157533615 0.2464140439 0.537060335 1 246096244 246096423 180 - 0.000 0.215 13.781
ENSG00000185420 E026 21.5331819 0.0009353373 0.5487251126 0.793621523 1 246186743 246186942 200 - 1.278 1.323 0.157
ENSG00000185420 E027 0.3804973 0.0159201241 0.4082741789   1 246193675 246193730 56 - 0.000 0.170 13.413
ENSG00000185420 E028 0.1176306 0.0117624412 0.2081059985   1 246218777 246218813 37 - 0.138 0.000 -14.583
ENSG00000185420 E029 0.1265070 0.0124183662 1.0000000000   1 246305919 246306009 91 - 0.000 0.065 11.960
ENSG00000185420 E030 1.1159691 0.0116503731 0.8191272350 0.934151107 1 246325813 246326395 583 - 0.327 0.293 -0.223
ENSG00000185420 E031 0.1268540 0.0122892694 1.0000000000   1 246326764 246327200 437 - 0.000 0.065 11.960
ENSG00000185420 E032 7.0365538 0.0020263125 0.1561027853 0.422292603 1 246327201 246327332 132 - 0.965 0.820 -0.554
ENSG00000185420 E033 2.6843024 0.0060643475 0.0169451648 0.113629307 1 246327333 246327337 5 - 0.739 0.415 -1.486
ENSG00000185420 E034 4.8998333 0.0098461123 0.0097702198 0.079097424 1 246330480 246330537 58 - 0.928 0.624 -1.223
ENSG00000185420 E035 7.2526753 0.0054103050 0.0117208738 0.089236816 1 246335367 246335474 108 - 1.045 0.787 -0.978
ENSG00000185420 E036 2.2055630 0.0132615516 0.0807428619 0.292012708 1 246355031 246355094 64 - 0.640 0.388 -1.223
ENSG00000185420 E037 0.0000000       1 246355181 246355335 155 -      
ENSG00000185420 E038 0.2458395 0.0166120893 0.5028189453   1 246417296 246417409 114 - 0.138 0.065 -1.223
ENSG00000185420 E039 0.0000000       1 246483435 246483765 331 -      
ENSG00000185420 E040 7.1329781 0.0023116560 0.0162626577 0.110802195 1 246507054 246507312 259 - 1.030 0.787 -0.924

Help

Please Click HERE to learn more details about the results from DEXseq.