ENSG00000185591

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000327443 ENSG00000185591 No_inf pgKDN_inf SP1 protein_coding protein_coding 16.53886 17.66014 15.56347 0.6544637 0.3735339 -0.1822233 1.889460 0.000000 4.924341 0.0000000 2.8595788 8.9467136 0.1200583 0.00000 0.313475 0.313475 0.48727603 0.04260385 FALSE TRUE
ENST00000426431 ENSG00000185591 No_inf pgKDN_inf SP1 protein_coding protein_coding 16.53886 17.66014 15.56347 0.6544637 0.3735339 -0.1822233 5.194172 2.434394 3.104928 1.0160656 2.2535695 0.3497219 0.3187250 0.14485 0.199450 0.054600 0.89948041 0.04260385 FALSE TRUE
MSTRG.6562.5 ENSG00000185591 No_inf pgKDN_inf SP1 protein_coding   16.53886 17.66014 15.56347 0.6544637 0.3735339 -0.1822233 3.516419 8.345876 2.203382 1.1503196 2.2033817 -1.9165389 0.2041417 0.46735 0.145075 -0.322275 0.04260385 0.04260385 FALSE TRUE
MSTRG.6562.6 ENSG00000185591 No_inf pgKDN_inf SP1 protein_coding   16.53886 17.66014 15.56347 0.6544637 0.3735339 -0.1822233 5.803816 6.879869 5.330816 0.5600573 0.6122983 -0.3674163 0.3492833 0.38780 0.342000 -0.045800 0.86423132 0.04260385 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000185591 E001 0.6005941 1.542316e-01 1.565879e-01 0.4229261430 12 53380176 53380298 123 + 0.319 0.087 -2.296
ENSG00000185591 E002 0.0000000       12 53380639 53380684 46 +      
ENSG00000185591 E003 0.6152580 1.470377e-02 8.258902e-01 0.9369342905 12 53380819 53380840 22 + 0.188 0.221 0.289
ENSG00000185591 E004 1.5808912 8.835734e-03 2.359421e-01 0.5252886246 12 53381217 53381301 85 + 0.501 0.323 -0.974
ENSG00000185591 E005 5.3529019 2.596398e-03 6.225044e-02 0.2505907731 12 53381302 53381658 357 + 0.906 0.697 -0.826
ENSG00000185591 E006 7.8111646 1.155276e-02 9.612729e-02 0.3229431569 12 53381659 53381813 155 + 1.032 0.857 -0.658
ENSG00000185591 E007 5.3391681 2.057866e-02 2.394017e-02 0.1416709756 12 53382110 53382218 109 + 0.934 0.657 -1.103
ENSG00000185591 E008 2.9064364 2.021070e-02 4.307379e-02 0.2024031709 12 53382219 53382253 35 + 0.727 0.442 -1.296
ENSG00000185591 E009 65.4953196 7.636354e-04 1.212219e-02 0.0910963059 12 53382254 53383622 1369 + 1.869 1.776 -0.312
ENSG00000185591 E010 12.0318105 3.275528e-03 8.503701e-01 0.9469820549 12 53406585 53406753 169 + 1.121 1.104 -0.060
ENSG00000185591 E011 15.1150384 2.445376e-03 7.627519e-01 0.9074283128 12 53409362 53409561 200 + 1.216 1.193 -0.084
ENSG00000185591 E012 503.3451996 7.124329e-05 9.476757e-06 0.0003255538 12 53410927 53416446 5520 + 2.684 2.709 0.086

Help

Please Click HERE to learn more details about the results from DEXseq.