ENSG00000185619

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000362003 ENSG00000185619 No_inf pgKDN_inf PCGF3 protein_coding protein_coding 25.64088 25.71076 24.89011 2.043016 1.235492 -0.04678091 6.242600 9.366619 5.0172392 1.3677564 2.1760455 -0.8993015 0.24793333 0.376000 0.205225 -0.170775 6.533950e-01 2.83427e-15 FALSE TRUE
ENST00000440452 ENSG00000185619 No_inf pgKDN_inf PCGF3 protein_coding nonsense_mediated_decay 25.64088 25.71076 24.89011 2.043016 1.235492 -0.04678091 3.037434 3.340819 1.9063938 1.3030058 1.2882755 -0.8061198 0.11445000 0.124950 0.073800 -0.051150 8.221554e-01 2.83427e-15 TRUE TRUE
ENST00000470161 ENSG00000185619 No_inf pgKDN_inf PCGF3 protein_coding protein_coding 25.64088 25.71076 24.89011 2.043016 1.235492 -0.04678091 5.448367 0.000000 9.1038628 0.0000000 0.9846739 9.8319188 0.21243333 0.000000 0.363550 0.363550 2.834270e-15 2.83427e-15 FALSE TRUE
ENST00000475288 ENSG00000185619 No_inf pgKDN_inf PCGF3 protein_coding retained_intron 25.64088 25.71076 24.89011 2.043016 1.235492 -0.04678091 1.636604 1.849988 0.4148443 0.7690008 0.2395161 -2.1302869 0.06184167 0.067375 0.016650 -0.050725 4.593451e-01 2.83427e-15   FALSE
MSTRG.21411.3 ENSG00000185619 No_inf pgKDN_inf PCGF3 protein_coding   25.64088 25.71076 24.89011 2.043016 1.235492 -0.04678091 3.284523 1.984733 3.7711832 1.4968972 2.1810602 0.9226422 0.12360833 0.070950 0.142075 0.071125 9.548660e-01 2.83427e-15 FALSE TRUE
MSTRG.21411.5 ENSG00000185619 No_inf pgKDN_inf PCGF3 protein_coding   25.64088 25.71076 24.89011 2.043016 1.235492 -0.04678091 3.982033 5.841324 3.4393547 1.5249595 1.0642420 -0.7624365 0.16296667 0.246200 0.142125 -0.104075 8.048429e-01 2.83427e-15 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000185619 E001 0.0000000       4 705748 705781 34 +      
ENSG00000185619 E002 0.0000000       4 705782 705783 2 +      
ENSG00000185619 E003 0.2356421 0.0155667075 1.378348e-01   4 705784 705809 26 + 0.200 0.000 -11.334
ENSG00000185619 E004 0.6174291 0.2956036655 9.156758e-01 0.9735655221 4 705810 705826 17 + 0.200 0.208 0.068
ENSG00000185619 E005 0.9904049 0.0335979253 8.643303e-01 0.9530875768 4 705827 705831 5 + 0.274 0.306 0.219
ENSG00000185619 E006 4.5114503 0.0045658948 5.234203e-02 0.2273142192 4 705832 705874 43 + 0.854 0.631 -0.910
ENSG00000185619 E007 6.0027861 0.0288704917 1.983604e-01 0.4797690160 4 705875 705942 68 + 0.920 0.772 -0.577
ENSG00000185619 E008 2.3337403 0.0282017766 5.728865e-01 0.8085957951 4 705943 705970 28 + 0.561 0.484 -0.366
ENSG00000185619 E009 0.0000000       4 725107 725229 123 +      
ENSG00000185619 E010 3.8953707 0.0037209582 3.490790e-02 0.1787111991 4 730630 730668 39 + 0.817 0.563 -1.066
ENSG00000185619 E011 0.0000000       4 730952 730969 18 +      
ENSG00000185619 E012 16.4387311 0.0009656309 1.238657e-04 0.0028283536 4 730970 731110 141 + 1.372 1.109 -0.927
ENSG00000185619 E013 1.8861833 0.0559910325 3.479489e-02 0.1782849749 4 731111 731345 235 + 0.200 0.563 2.183
ENSG00000185619 E014 2.6664338 0.0082332108 3.362224e-02 0.1744139347 4 732400 732443 44 + 0.708 0.421 -1.325
ENSG00000185619 E015 4.7651271 0.0620184054 2.192356e-01 0.5058767484 4 732444 732498 55 + 0.854 0.670 -0.740
ENSG00000185619 E016 21.2173206 0.0032118293 1.206172e-04 0.0027682416 4 733672 733789 118 + 1.469 1.224 -0.851
ENSG00000185619 E017 3.7913744 0.0078099786 2.294011e-01 0.5180435159 4 733790 733883 94 + 0.755 0.609 -0.611
ENSG00000185619 E018 44.6476295 0.0003335082 1.915723e-06 0.0000818721 4 733884 734789 906 + 1.498 1.726 0.776
ENSG00000185619 E019 8.6004011 0.0017085576 1.165586e-02 0.0888798321 4 734790 734930 141 + 0.797 1.058 0.984
ENSG00000185619 E020 16.4486788 0.0013801110 1.387963e-01 0.3961811188 4 734931 735027 97 + 1.289 1.191 -0.346
ENSG00000185619 E021 15.2210398 0.0126544322 3.025486e-01 0.5956652797 4 737466 737521 56 + 1.248 1.167 -0.285
ENSG00000185619 E022 0.3810317 0.0247474306 2.017389e-01   4 737522 737540 19 + 0.000 0.208 12.271
ENSG00000185619 E023 27.5587405 0.0006980602 1.163707e-02 0.0888119220 4 743474 743584 111 + 1.521 1.390 -0.454
ENSG00000185619 E024 0.1268540 0.0123380055 7.924598e-01   4 743865 743952 88 + 0.000 0.081 10.819
ENSG00000185619 E025 14.4316309 0.0170643550 6.541280e-02 0.2576043163 4 744600 744688 89 + 1.269 1.109 -0.566
ENSG00000185619 E026 0.0000000       4 761279 761416 138 +      
ENSG00000185619 E027 0.0000000       4 764984 765064 81 +      
ENSG00000185619 E028 0.1268540 0.0123380055 7.924598e-01   4 766032 766034 3 + 0.000 0.081 10.819
ENSG00000185619 E029 15.2705015 0.0082125765 1.239704e-02 0.0922673853 4 766035 766405 371 + 1.308 1.116 -0.680
ENSG00000185619 E030 0.0000000       4 766406 766673 268 +      
ENSG00000185619 E031 62.5196258 0.0048787361 3.724217e-01 0.6603173504 4 766674 768188 1515 + 1.762 1.812 0.167
ENSG00000185619 E032 202.9557259 0.0020858005 8.244442e-05 0.0020239224 4 768189 770815 2627 + 2.244 2.332 0.296

Help

Please Click HERE to learn more details about the results from DEXseq.